ES8203965A1 - Un procedimiento para la obtencion de un peptido. - Google Patents

Un procedimiento para la obtencion de un peptido.

Info

Publication number
ES8203965A1
ES8203965A1 ES498948A ES498948A ES8203965A1 ES 8203965 A1 ES8203965 A1 ES 8203965A1 ES 498948 A ES498948 A ES 498948A ES 498948 A ES498948 A ES 498948A ES 8203965 A1 ES8203965 A1 ES 8203965A1
Authority
ES
Spain
Prior art keywords
attachment
synthetic gene
asparagyl
phenylalanine
self
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES498948A
Other languages
English (en)
Other versions
ES498948A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of ES8203965A1 publication Critical patent/ES8203965A1/es
Publication of ES498948A0 publication Critical patent/ES498948A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/20—Aspartic acid; Asparagine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/222—Phenylalanine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN PEPTIDO, CODIFICADO POR UN GEN SINTETICO, QUE CONTIENE CODONES PARA LOS AMINOACIDOS DEL PEPTIDO, REPETIDOS EN UNA PROGRESION LINEAL A LO LARGO DE LA MOLECULA DE ADN, CON LA MISMA POLARIDAD Y SIN INTERRUPCION. CONSISTE EN EL AUTOENSAMBLAJE, UNION Y, OPCIONALMENTE, REPARACION DE UNA PLURALIDAD DE OLIGONUCLEOTIDOS ADECUADOS. EL ENSAMBLAJE SE CONSIGUE POR SUPERPOSICION AUTOCOMPLEMENTARIA DE EXTREMOS EN LOS TERMINALES DEL GRUPO DE OLIGONUCLEOTIDOS QUE, ENSAMBLADOS, CONSTITUYEN LA UNIDAD REPETIDA DEL GEN.
ES498948A 1980-01-30 1981-01-29 Un procedimiento para la obtencion de un peptido. Granted ES498948A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8003191 1980-01-30

Publications (2)

Publication Number Publication Date
ES8203965A1 true ES8203965A1 (es) 1982-04-16
ES498948A0 ES498948A0 (es) 1982-04-16

Family

ID=10511011

Family Applications (1)

Application Number Title Priority Date Filing Date
ES498948A Granted ES498948A0 (es) 1980-01-30 1981-01-29 Un procedimiento para la obtencion de un peptido.

Country Status (14)

Country Link
JP (1) JPS579795A (es)
AU (1) AU545908B2 (es)
BE (1) BE887290A (es)
CA (1) CA1189466A (es)
CH (1) CH662821A5 (es)
DE (1) DE3102721A1 (es)
DK (1) DK17881A (es)
ES (1) ES498948A0 (es)
FR (1) FR2479259B1 (es)
IE (1) IE50833B1 (es)
IL (1) IL61952A (es)
IT (1) IT1170653B (es)
NL (1) NL8100437A (es)
SE (1) SE451595B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2052516B (en) * 1979-06-01 1983-06-29 Searle & Co Plasmid vectors production and use thereof
CA1213537A (en) * 1984-05-01 1986-11-04 Canadian Patents And Development Limited - Societe Canadienne Des Brevets Et D'exploitation Limitee Polypeptide expression method
AU5762699A (en) * 1998-09-19 2000-04-10 Sang Jun Lee Dna cassette encoding a multimer of a biologically active peptide and a cleavable linker attached thereto and process for preparing the biologically active peptide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0036258A3 (en) * 1980-03-14 1982-02-10 Cetus Corporation Process for producing aspartame

Also Published As

Publication number Publication date
DE3102721A1 (de) 1982-01-07
SE8100238L (sv) 1981-07-31
CA1189466A (en) 1985-06-25
SE451595B (sv) 1987-10-19
IL61952A (en) 1984-09-30
FR2479259A1 (fr) 1981-10-02
AU545908B2 (en) 1985-08-08
ES498948A0 (es) 1982-04-16
DK17881A (da) 1981-07-31
IT1170653B (it) 1987-06-03
FR2479259B1 (fr) 1985-07-12
AU6650781A (en) 1981-08-06
IT8147639A0 (it) 1981-01-27
CH662821A5 (fr) 1987-10-30
BE887290A (fr) 1981-05-14
IE50833B1 (en) 1986-07-23
IL61952A0 (en) 1981-02-27
IE810071L (en) 1981-07-30
DE3102721C2 (es) 1988-11-10
JPS579795A (en) 1982-01-19
NL8100437A (nl) 1981-09-01

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506