ES8203914A1 - Procedimiento para obtener relaxina humana - Google Patents

Procedimiento para obtener relaxina humana

Info

Publication number
ES8203914A1
ES8203914A1 ES498941A ES498941A ES8203914A1 ES 8203914 A1 ES8203914 A1 ES 8203914A1 ES 498941 A ES498941 A ES 498941A ES 498941 A ES498941 A ES 498941A ES 8203914 A1 ES8203914 A1 ES 8203914A1
Authority
ES
Spain
Prior art keywords
human relaxin
obtaining human
fetal membranes
membranes
relaxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES498941A
Other languages
English (en)
Other versions
ES498941A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Serono Argentina SA
Original Assignee
Serono Argentina SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serono Argentina SA filed Critical Serono Argentina SA
Publication of ES8203914A1 publication Critical patent/ES8203914A1/es
Publication of ES498941A0 publication Critical patent/ES498941A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/85—Reproductive organs or embryos
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/85—Reproductive organs or embryos
    • Y10S530/851—Placenta; amniotic fluid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/85—Reproductive organs or embryos
    • Y10S530/852—Sperm
    • Y10S530/853—Ovary; eggs; embryos

Abstract

PROCEDIMIENTO PARA OBTENER RELAXINA HUMANA A PARTIR DE MEMBRANAS FETALES. EL MATERIAL BASICO QUE SE UTILIZA ES UNA MEMBRANA FETAL OBTENIDA DESPUES DE CADA PARTO Y SE CONSERVA HASTA SU TRATAMIENTO A -30 GRADOS C. LA PRIMERA DE LAS TRES CAPAS DE QUE CONSTA LA MEMBRANA FETAL, EL AMNION, SE SEPARA DE LAS OTRAS DOS POR DELAMINACION, QUEDANDO ASOCIADAS LAS OTRAS DOS, CORIONDECIDUA, QUE SE TRITURAN Y HOMOGENEIZAN. TRAS ELLO SE PRODUCE LA PRECIPITACION Y EL DESECHAMIENTO DE RESIDUOS DE TEJIDOS Y DE LOS MAS PESADOS ORGANELOS CELULARES PARA OBTENER UN EXTRACTO DE RELAXINA. SE UTILIZA TERAPEUTICAMENTE EN CONDICIONES PATOLOGICAS DE EMBARAZO Y DE TEJIDO DE INMUNOENSAYO RADIOLOGICO.
ES498941A 1980-02-01 1981-01-29 Procedimiento para obtener relaxina humana Granted ES498941A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/117,444 US4267101A (en) 1980-02-01 1980-02-01 Process for obtaining human relaxin from fetal membranes

Publications (2)

Publication Number Publication Date
ES8203914A1 true ES8203914A1 (es) 1982-05-01
ES498941A0 ES498941A0 (es) 1982-05-01

Family

ID=22372986

Family Applications (1)

Application Number Title Priority Date Filing Date
ES498941A Granted ES498941A0 (es) 1980-02-01 1981-01-29 Procedimiento para obtener relaxina humana

Country Status (18)

Country Link
US (1) US4267101A (es)
JP (1) JPS56127315A (es)
AR (2) AR227907A1 (es)
AT (1) AT372856B (es)
AU (1) AU540310B2 (es)
BE (1) BE887324A (es)
CA (1) CA1143286A (es)
CH (1) CH647530A5 (es)
DE (1) DE3102487C2 (es)
DK (1) DK44181A (es)
ES (1) ES498941A0 (es)
FR (1) FR2475047A1 (es)
GB (1) GB2068383B (es)
IL (1) IL61931A (es)
IT (1) IT8147648A0 (es)
NL (1) NL8100243A (es)
SE (1) SE8100614L (es)
ZA (1) ZA81374B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053488A (en) * 1982-08-12 1991-10-01 Howard Florey Institute Of Experimental Physiology & Medicine Molecular cloning and characterization of a gene sequence coding for human relaxin
US5320953A (en) * 1982-08-12 1994-06-14 Howard Florey Institute Of Experimental Physiology And Medicine Process for synthesizing human H1-prorelaxin, H1-relaxin and fusion proteins thereof
EP0287820B1 (en) * 1982-08-12 1992-07-08 Howard Florey Institute Of Experimental Physiology And Medicine Human relaxin analogues
DE3236264A1 (de) * 1982-09-30 1984-04-05 Serono Pharmazeutische Präparate GmbH, 7800 Freiburg Verfahren zur gewinnung von relaxin
NZ206534A (en) * 1982-12-13 1988-05-30 Florey Howard Inst Molecular cloning and characterisation of gene sequence coding for human relaxin
US5023321A (en) * 1982-12-13 1991-06-11 Howard Florey Institute Of Experimental Physiology & Medicine Molecular cloning and characterization of a further gene sequence coding for human relaxin
AU612594B2 (en) * 1986-09-12 1991-07-18 Genentech Inc. Human prorelaxin
AU626840B2 (en) * 1988-02-26 1992-08-13 Genentech Inc. Human relaxin formulation
US6348327B1 (en) * 1991-12-06 2002-02-19 Genentech, Inc. Non-endocrine animal host cells capable of expressing variant proinsulin and processing the same to form active, mature insulin and methods of culturing such cells
US5612051A (en) * 1995-11-17 1997-03-18 Yue; Samuel K. Method of treating involuntary muscle dysfunction with relaxin hormone
US6251863B1 (en) 1998-09-08 2001-06-26 Samuel K. Yue Method of preventing and treating symptoms of aging and neurodegenerative dysfunctions with relaxin
AU2005247332A1 (en) * 2004-04-30 2005-12-08 Corthera, Inc. Methods and compositions for control of fetal growth via modulation of relaxin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2852432A (en) * 1953-08-11 1958-09-16 Warner Lambert Pharmaceutical Process for purification of relaxin by ion exchange
US2852431A (en) * 1954-05-17 1958-09-16 Warner Lambert Pharmaceutical Process for the extraction and purification of relaxin using trichloracetic acid
US2930737A (en) * 1955-11-15 1960-03-29 Princeton Lab Inc Process for the isolation of relaxin using glacial acetic acid
US2995494A (en) * 1957-12-27 1961-08-08 Ortho Pharma Corp Process for purifying relaxin

Also Published As

Publication number Publication date
DE3102487A1 (de) 1982-01-07
FR2475047A1 (fr) 1981-08-07
AT372856B (de) 1983-11-25
US4267101A (en) 1981-05-12
IT8147648A0 (it) 1981-01-28
CH647530A5 (de) 1985-01-31
SE8100614L (sv) 1981-08-02
JPS6157809B2 (es) 1986-12-09
DK44181A (da) 1981-08-02
JPS56127315A (en) 1981-10-06
GB2068383B (en) 1983-05-11
CA1143286A (en) 1983-03-22
AR227907A1 (es) 1982-12-30
AU6661481A (en) 1981-08-06
NL8100243A (nl) 1981-09-01
IL61931A (en) 1984-06-29
ATA26281A (de) 1983-04-15
ES498941A0 (es) 1982-05-01
FR2475047B1 (es) 1983-07-29
AR227959A1 (es) 1982-12-30
AU540310B2 (en) 1984-11-08
IL61931A0 (en) 1981-02-27
ZA81374B (en) 1982-08-25
BE887324A (fr) 1981-05-14
DE3102487C2 (de) 1983-06-16
GB2068383A (en) 1981-08-12

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