ES8203225A1 - Procedimiento para aislar antigenos glicoproteicos de un vi-rus - Google Patents
Procedimiento para aislar antigenos glicoproteicos de un vi-rusInfo
- Publication number
- ES8203225A1 ES8203225A1 ES502549A ES502549A ES8203225A1 ES 8203225 A1 ES8203225 A1 ES 8203225A1 ES 502549 A ES502549 A ES 502549A ES 502549 A ES502549 A ES 502549A ES 8203225 A1 ES8203225 A1 ES 8203225A1
- Authority
- ES
- Spain
- Prior art keywords
- vaccines
- preparation
- glycoproteic
- antigens
- isolating viral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 230000003612 virological effect Effects 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title 1
- 239000003599 detergent Substances 0.000 abstract 3
- 241000700605 Viruses Species 0.000 abstract 2
- 239000008346 aqueous phase Substances 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000012071 phase Substances 0.000 abstract 1
- 238000005191 phase separation Methods 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PROCEDIMIENTO PARA AISLAR ANTIGENOS GLICOPROTEICOS DE UN VIRUS. CONSISTE EN TRATAR EL VIRUS CON UNA SOLUCION ACUOSA DE DETERGENTO NO IONICO, SEPARANDO A CONTINUACION LAS PARTICULAS VIRALES Y ELIMINANDO EL DETERGENTE; PARA LO CUAL SE EFECTUA UNA SEPARACION PRO FASES, ENTRE UNA FASE ACUOSA Y OTRA CONSTITUIDA POR UN ALCOHOL SUPERIOR INSOLUBLE EN AGUA, RECUPERANDOSE LOS ANTIGENOS GLICOPROTEICOS EN LA FASE ACUOSA. EL DETERGENTE EMPLEADO ES UN OCTILFENOXIPOLIETOXIETANOL. LAS FASES ACUOSAS SEPARADAS DEL ALCOHOL SUPERIOR INSOLUBLE EN AGUA, SON LAVADAS CON ETER; DICAH FASE ACUOSA ESTA CONSTITUIDA POR UN TAMPON FOSFATICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8012522A FR2483779A1 (fr) | 1980-06-05 | 1980-06-05 | Procede pour isoler des antigenes glycoproteiques viraux et son application a la preparation de vaccins |
Publications (2)
Publication Number | Publication Date |
---|---|
ES502549A0 ES502549A0 (es) | 1982-04-01 |
ES8203225A1 true ES8203225A1 (es) | 1982-04-01 |
Family
ID=9242745
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES502549A Expired ES8203225A1 (es) | 1980-06-05 | 1981-05-27 | Procedimiento para aislar antigenos glicoproteicos de un vi-rus |
Country Status (19)
Country | Link |
---|---|
US (1) | US4344935A (es) |
EP (1) | EP0041880B1 (es) |
JP (1) | JPS5726624A (es) |
AR (1) | AR228865A1 (es) |
AT (1) | ATE3239T1 (es) |
AU (1) | AU546088B2 (es) |
CA (1) | CA1174598A (es) |
DE (1) | DE3160264D1 (es) |
DK (1) | DK228081A (es) |
ES (1) | ES8203225A1 (es) |
FI (1) | FI811685L (es) |
FR (1) | FR2483779A1 (es) |
GR (1) | GR74610B (es) |
IE (1) | IE51226B1 (es) |
IL (1) | IL62913A (es) |
NO (1) | NO811873L (es) |
NZ (1) | NZ197306A (es) |
PT (1) | PT73032B (es) |
ZA (1) | ZA813479B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4721675A (en) * | 1982-02-01 | 1988-01-26 | Abbott Laboratories | Production of hepatitis A virus in vitro utilizing a persistently virus infected cell culture system |
US4645666A (en) * | 1982-06-08 | 1987-02-24 | The Regents Of The University Of California | Vaccine for bluetongue disease employing platinum compounds |
GB8502096D0 (en) * | 1985-01-28 | 1985-02-27 | Medical Res Council | Influenza vaccine |
NZ224422A (en) | 1987-05-05 | 1990-11-27 | Molecular Eng Ass | Composition adapted for intranasal immunisation against viral infection comprising a glycoprotein complexed with a lipid |
US4909940A (en) * | 1987-12-30 | 1990-03-20 | New York Blood Center, Inc. | Extraction of process chemicals from labile biological mixtures with organic alcohols or with halogenated hydrocarbons |
US4975119A (en) * | 1989-04-25 | 1990-12-04 | Rheox, Inc. | Liquid antisettling agents for organic coating compositions |
FR2671974A1 (fr) * | 1991-01-24 | 1992-07-31 | Pasteur Merieux Serums Vacc | Composition vaccinale contre la grippe, a effet synergique, contenant comme additif du core de virus grippal. |
US5741493A (en) * | 1991-01-24 | 1998-04-21 | Pasteur Merieux Serums Et Vaccins | Vaccine composition against influenza, with synergic effects, containing influenza virus core as an additive |
US6780630B1 (en) * | 1992-07-10 | 2004-08-24 | Baylor College Of Medicine | Parenteral immunization against rotavirus |
FR2723740B1 (fr) * | 1994-08-16 | 1996-11-08 | Pasteur Merieux Serums Vacc | Procede de preparation d'antigenes du virus grippal, antigenes obtenus et leurs applications |
DE69629812T2 (de) | 1995-06-14 | 2004-04-01 | Baylor College Of Medicine, Houston | Impfstoff gegen rotavirus infektionen enthaltend peptide des viralenterotoxines nsp4 |
US6673355B1 (en) | 1995-06-14 | 2004-01-06 | Baylor College Of Medicine | Rotavirus enterotoxin NSP4 and methods of using same |
DE19938767C2 (de) * | 1999-08-16 | 2002-10-24 | Tad Pharma Gmbh | Spaltimpfstoffe |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE661402A (es) | 1964-03-20 | |||
US3847737A (en) * | 1965-03-22 | 1974-11-12 | A Kanarek | Inactivation of myxoviruses and method of preparing a vaccine therefrom |
US3629470A (en) * | 1968-04-08 | 1971-12-21 | Burroughs Wellcome Co | Process for purification of animal rna viruses |
BR6915288D0 (pt) * | 1969-03-15 | 1973-02-08 | Bayer Ag | Processo para a purificacao de solucoes do virus da febre aftosa |
US3989818A (en) * | 1970-08-14 | 1976-11-02 | South African Inventions Development Corporation | Influenza virus vaccine |
US3790552A (en) * | 1972-03-16 | 1974-02-05 | Us Health | Method of removing hepatitis-associated antigen from a protein fraction using polyethylene glycol |
US3962421A (en) * | 1973-06-18 | 1976-06-08 | American Home Products Corporation | Method for the disruption of lipid-containing viruses |
GB1486557A (en) | 1973-10-18 | 1977-09-21 | Flockhart & Co | Process for the preparation of pyrogen-free sub-unit vaccine |
US3951937A (en) * | 1973-12-20 | 1976-04-20 | The Community Blood Council Of Greater New York, Inc. | Large scale purification of hepatitis type B antigen using polyethylene glycol |
US4064232A (en) * | 1974-01-14 | 1977-12-20 | Sandoz Ltd. | Process for isolating the immunogenic components of influenza viruses |
US4140762A (en) * | 1974-01-14 | 1979-02-20 | Sandoz Ltd. | Influenza sub-unit vaccine |
AU507149B2 (en) | 1975-01-16 | 1980-02-07 | Mount Sinai School Of Medicine Of The City University Of New York, The | Method of influenza immunization |
FR2422720A2 (fr) | 1977-04-26 | 1979-11-09 | Elf Aquitaine | Separation et purification de proteines par chromatographie |
FI66020C (fi) * | 1977-09-19 | 1984-08-10 | Merck & Co Inc | Foerfarande foer framstaellning av antigeniska immunogeniska subunits av hsv-1 och hsv-2 |
DE2750045A1 (de) * | 1977-11-09 | 1979-05-10 | Behringwerke Ag | Verfahren zur entfernung von detergentien aus virusantigensuspensionen |
-
1980
- 1980-06-05 FR FR8012522A patent/FR2483779A1/fr active Granted
-
1981
- 1981-05-11 AR AR285278A patent/AR228865A1/es active
- 1981-05-14 PT PT73032A patent/PT73032B/pt unknown
- 1981-05-19 US US06/265,084 patent/US4344935A/en not_active Expired - Fee Related
- 1981-05-20 IL IL62913A patent/IL62913A/xx unknown
- 1981-05-22 AT AT81400815T patent/ATE3239T1/de not_active IP Right Cessation
- 1981-05-22 DE DE8181400815T patent/DE3160264D1/de not_active Expired
- 1981-05-22 EP EP81400815A patent/EP0041880B1/fr not_active Expired
- 1981-05-25 ZA ZA00813479A patent/ZA813479B/xx unknown
- 1981-05-25 DK DK228081A patent/DK228081A/da not_active Application Discontinuation
- 1981-05-26 IE IE1168/81A patent/IE51226B1/en unknown
- 1981-05-27 ES ES502549A patent/ES8203225A1/es not_active Expired
- 1981-05-29 AU AU71170/81A patent/AU546088B2/en not_active Ceased
- 1981-06-01 FI FI811685A patent/FI811685L/fi not_active Application Discontinuation
- 1981-06-02 GR GR65127A patent/GR74610B/el unknown
- 1981-06-02 CA CA000378801A patent/CA1174598A/en not_active Expired
- 1981-06-03 NO NO811873A patent/NO811873L/no unknown
- 1981-06-04 NZ NZ197306A patent/NZ197306A/en unknown
- 1981-06-04 JP JP8504581A patent/JPS5726624A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
PT73032B (fr) | 1982-07-01 |
EP0041880A1 (fr) | 1981-12-16 |
AU546088B2 (en) | 1985-08-15 |
IE811168L (en) | 1981-12-05 |
IL62913A0 (en) | 1981-07-31 |
PT73032A (fr) | 1981-06-01 |
EP0041880B1 (fr) | 1983-05-11 |
FI811685L (fi) | 1981-12-06 |
FR2483779A1 (fr) | 1981-12-11 |
DK228081A (da) | 1981-12-06 |
DE3160264D1 (en) | 1983-06-16 |
GR74610B (es) | 1984-06-29 |
AR228865A1 (es) | 1983-04-29 |
CA1174598A (en) | 1984-09-18 |
JPS5726624A (en) | 1982-02-12 |
AU7117081A (en) | 1981-12-10 |
US4344935A (en) | 1982-08-17 |
NO811873L (no) | 1981-12-07 |
ES502549A0 (es) | 1982-04-01 |
NZ197306A (en) | 1984-03-16 |
IL62913A (en) | 1984-08-31 |
IE51226B1 (en) | 1986-11-12 |
ATE3239T1 (de) | 1983-05-15 |
FR2483779B1 (es) | 1983-07-22 |
ZA813479B (en) | 1982-06-30 |
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