ES8202817A1 - Metodo para preparar 2-(2-(4-(3-cloro-4-fluorofenil)-1-pipe-racinil)propil)-1,2,4-triazolo(4,3-a)piridin-3(2h)-ona y sussales - Google Patents
Metodo para preparar 2-(2-(4-(3-cloro-4-fluorofenil)-1-pipe-racinil)propil)-1,2,4-triazolo(4,3-a)piridin-3(2h)-ona y sussalesInfo
- Publication number
- ES8202817A1 ES8202817A1 ES501188A ES501188A ES8202817A1 ES 8202817 A1 ES8202817 A1 ES 8202817A1 ES 501188 A ES501188 A ES 501188A ES 501188 A ES501188 A ES 501188A ES 8202817 A1 ES8202817 A1 ES 8202817A1
- Authority
- ES
- Spain
- Prior art keywords
- triazolo
- piperazinyl
- fluorophenyl
- chloro
- propyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BKQVYAICJGAANI-UHFFFAOYSA-N 2-[3-[4-(3-chloro-4-fluorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one Chemical compound C1=C(Cl)C(F)=CC=C1N1CCN(CCCN2C(N3C=CC=CC3=N2)=O)CC1 BKQVYAICJGAANI-UHFFFAOYSA-N 0.000 title abstract 2
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229960003965 antiepileptics Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21246/80A IT1147349B (it) | 1980-04-09 | 1980-04-09 | 2-parentesi quadra aperta 3-parentesi quadra aperta 4-(3-cloro-4-fluorofenil)-1-piperfrazinil parentesi quadra propil parentesi quadra chiusa-1,2,4-triazolo parentesi quadra aperta 4,3 parentesi quadra chiusa piridin-3(2h)-one |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES501188A0 ES501188A0 (es) | 1982-02-01 |
| ES8202817A1 true ES8202817A1 (es) | 1982-02-01 |
Family
ID=11178966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES501188A Expired ES8202817A1 (es) | 1980-04-09 | 1981-04-08 | Metodo para preparar 2-(2-(4-(3-cloro-4-fluorofenil)-1-pipe-racinil)propil)-1,2,4-triazolo(4,3-a)piridin-3(2h)-ona y sussales |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4402956A (enEXAMPLES) |
| JP (1) | JPS56158784A (enEXAMPLES) |
| KR (1) | KR840002292B1 (enEXAMPLES) |
| AR (1) | AR225076A1 (enEXAMPLES) |
| AT (1) | AT377262B (enEXAMPLES) |
| AU (1) | AU529605B2 (enEXAMPLES) |
| BE (1) | BE887547A (enEXAMPLES) |
| CA (1) | CA1176253A (enEXAMPLES) |
| CH (1) | CH652397A5 (enEXAMPLES) |
| DE (1) | DE3112984A1 (enEXAMPLES) |
| ES (1) | ES8202817A1 (enEXAMPLES) |
| FI (1) | FI69306C (enEXAMPLES) |
| FR (1) | FR2480285A1 (enEXAMPLES) |
| GB (1) | GB2073747B (enEXAMPLES) |
| GR (1) | GR73620B (enEXAMPLES) |
| IL (1) | IL62101A (enEXAMPLES) |
| IT (1) | IT1147349B (enEXAMPLES) |
| NL (1) | NL8100998A (enEXAMPLES) |
| PT (1) | PT72813B (enEXAMPLES) |
| SE (1) | SE442201B (enEXAMPLES) |
| YU (1) | YU83181A (enEXAMPLES) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1237172A (zh) * | 1996-11-12 | 1999-12-01 | 塞普拉科公司 | 2r,4s,r,s－和2s,4r,r,s－羟基伊曲康唑－和羟基沙波康唑衍生物 |
| EP0937071A1 (en) | 1996-11-12 | 1999-08-25 | Sepracor, Inc. | 2r,4s,s,s- and 2s,4r,s,s-hydroxyitraconazole |
| US6147077A (en) * | 1999-04-29 | 2000-11-14 | Sepracor Inc. | 2R,4S-hydroxyitraconazole isomers |
| EP2303897A4 (en) * | 2008-06-05 | 2012-02-22 | Harvard College | HIGH VALENCIA PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF |
| JP2012509351A (ja) | 2008-11-20 | 2012-04-19 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 有機化合物のフッ素化 |
| JP2012514655A (ja) * | 2009-01-09 | 2012-06-28 | プレジデント アンド フェローズ オブ ハーバード カレッジ | フッ素含有化合物およびその使用法 |
| WO2012142162A2 (en) | 2011-04-12 | 2012-10-18 | President And Fellows Of Harvard College | Fluorination of organic compounds |
| WO2014052622A1 (en) | 2012-09-26 | 2014-04-03 | President And Fellows Of Harvard College | Nickel fluorinating complexes and uses thereof |
| US10759764B2 (en) | 2013-10-18 | 2020-09-01 | President And Fellows Of Harvard College | Fluorination of organic compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1066857B (it) * | 1965-12-15 | 1985-03-12 | Acraf | Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione |
| FR8135M (enEXAMPLES) * | 1968-12-31 | 1970-08-10 | ||
| US4218458A (en) * | 1978-06-23 | 1980-08-19 | Janssen Pharmaceutica, N.V. | Heterocyclic derivatives of (4-aryloxy-methyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles |
| UST100505I4 (en) | 1980-03-17 | 1981-04-07 | Triazolo[4,3-a]pyridin-3(2H)-ones |
-
1980
- 1980-04-09 IT IT21246/80A patent/IT1147349B/it active
-
1981
- 1981-02-10 IL IL62101A patent/IL62101A/xx unknown
- 1981-02-12 US US06/234,065 patent/US4402956A/en not_active Expired - Fee Related
- 1981-02-17 BE BE0/203815A patent/BE887547A/fr not_active IP Right Cessation
- 1981-02-25 CH CH1240/81A patent/CH652397A5/it not_active IP Right Cessation
- 1981-03-02 NL NL8100998A patent/NL8100998A/nl not_active Application Discontinuation
- 1981-03-16 GB GB8108158A patent/GB2073747B/en not_active Expired
- 1981-03-30 CA CA000374133A patent/CA1176253A/en not_active Expired
- 1981-03-30 YU YU00831/81A patent/YU83181A/xx unknown
- 1981-04-01 DE DE19813112984 patent/DE3112984A1/de not_active Withdrawn
- 1981-04-01 SE SE8102093A patent/SE442201B/sv not_active IP Right Cessation
- 1981-04-01 FI FI811000A patent/FI69306C/fi not_active IP Right Cessation
- 1981-04-02 AU AU69043/81A patent/AU529605B2/en not_active Ceased
- 1981-04-07 PT PT72813A patent/PT72813B/pt unknown
- 1981-04-07 GR GR64614A patent/GR73620B/el unknown
- 1981-04-07 FR FR8106952A patent/FR2480285A1/fr active Granted
- 1981-04-07 KR KR1019810001166A patent/KR840002292B1/ko not_active Expired
- 1981-04-07 AR AR284885A patent/AR225076A1/es active
- 1981-04-08 ES ES501188A patent/ES8202817A1/es not_active Expired
- 1981-04-09 JP JP5420581A patent/JPS56158784A/ja active Pending
- 1981-04-09 AT AT0165081A patent/AT377262B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES501188A0 (es) | 1982-02-01 |
| NL8100998A (nl) | 1981-11-02 |
| FI69306B (fi) | 1985-09-30 |
| AR225076A1 (es) | 1982-02-15 |
| KR840002292B1 (ko) | 1984-12-15 |
| FI69306C (fi) | 1986-01-10 |
| US4402956A (en) | 1983-09-06 |
| IL62101A (en) | 1984-01-31 |
| SE8102093L (sv) | 1981-10-10 |
| AU529605B2 (en) | 1983-06-16 |
| BE887547A (fr) | 1981-06-15 |
| FI811000L (fi) | 1981-10-10 |
| CH652397A5 (it) | 1985-11-15 |
| DE3112984A1 (de) | 1981-12-24 |
| GR73620B (enEXAMPLES) | 1984-03-26 |
| PT72813A (en) | 1981-05-01 |
| ATA165081A (de) | 1984-07-15 |
| GB2073747B (en) | 1983-09-07 |
| FR2480285B1 (enEXAMPLES) | 1984-02-24 |
| SE442201B (sv) | 1985-12-09 |
| IT1147349B (it) | 1986-11-19 |
| IL62101A0 (en) | 1981-03-31 |
| YU83181A (en) | 1983-12-31 |
| PT72813B (en) | 1982-04-02 |
| IT8021246A0 (it) | 1980-04-09 |
| AT377262B (de) | 1985-02-25 |
| JPS56158784A (en) | 1981-12-07 |
| FR2480285A1 (fr) | 1981-10-16 |
| KR830005218A (ko) | 1983-08-03 |
| AU6904381A (en) | 1981-10-15 |
| CA1176253A (en) | 1984-10-16 |
| GB2073747A (en) | 1981-10-21 |
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