ES8201545A1 - Procedimiento para la preparacion de 2,2'-dihidroxi-5,5'-me-tilen-di-(acido para-toluenosulfonico) y sus sales - Google Patents

Procedimiento para la preparacion de 2,2'-dihidroxi-5,5'-me-tilen-di-(acido para-toluenosulfonico) y sus sales

Info

Publication number
ES8201545A1
ES8201545A1 ES497410A ES497410A ES8201545A1 ES 8201545 A1 ES8201545 A1 ES 8201545A1 ES 497410 A ES497410 A ES 497410A ES 497410 A ES497410 A ES 497410A ES 8201545 A1 ES8201545 A1 ES 8201545A1
Authority
ES
Spain
Prior art keywords
acid
cresol
salts
converted
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497410A
Other languages
English (en)
Other versions
ES497410A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Publication of ES8201545A1 publication Critical patent/ES8201545A1/es
Publication of ES497410A0 publication Critical patent/ES497410A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Phenolic Resins Or Amino Resins (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 2,2''-DIHIDROXI-5,5''-METILENDI-(ACIDO-P-TOLUENOSULFONICO) Y SUS SALES. CONSISTE EN LA REACCION DE ACIDO M-CRESOL-6-SULFONICO, Y/O SUS SALES, CON FORMALDEHIDO Y/O CON COMPUESTOS QUE LIBERAN FORMALDEHIDO. LA REACCION DE CONDENSACION CON EL FORMALDEHIDO SE LLEVA A CABO EN DISOLUCION ACUOSA A UNA TEMPERATURA COMPRENDIDA ENTRE 10 C Y 90 C. TAMBIEN SE PUEDE PARTIR DE LA SAL AMONICA O SODICA DEL ACIDO M-CRESOL-6-SULFONICO, REALIZANDO EN ESTE CAXO LA CONDENSACION CON FORMALDEHIDO EN PRESENCIA DE AMINAS ORGANICAS. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS EFECTOS ASTRINGENTES, BACTERICIDA, TRICOMONACIDA, FUNGICIDA Y HEMOSTIPTICO.
ES497410A 1979-12-04 1980-12-03 Procedimiento para la preparacion de 2,2'-dihidroxi-5,5'-me-tilen-di-(acido para-toluenosulfonico) y sus sales Granted ES497410A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1076379 1979-12-04

Publications (2)

Publication Number Publication Date
ES8201545A1 true ES8201545A1 (es) 1982-01-01
ES497410A0 ES497410A0 (es) 1982-01-01

Family

ID=4366580

Family Applications (1)

Application Number Title Priority Date Filing Date
ES497410A Granted ES497410A0 (es) 1979-12-04 1980-12-03 Procedimiento para la preparacion de 2,2'-dihidroxi-5,5'-me-tilen-di-(acido para-toluenosulfonico) y sus sales

Country Status (14)

Country Link
EP (1) EP0029990B1 (es)
JP (1) JPS56113754A (es)
AT (1) ATE1523T1 (es)
AU (1) AU535714B2 (es)
DE (1) DE3060828D1 (es)
DK (1) DK517580A (es)
ES (1) ES497410A0 (es)
GR (1) GR71617B (es)
IE (1) IE50610B1 (es)
IL (1) IL61600A (es)
NZ (1) NZ195716A (es)
PL (1) PL228235A1 (es)
PT (1) PT72160B (es)
ZA (1) ZA807544B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4605726B2 (ja) * 1997-09-02 2011-01-05 日本曹達株式会社 フェノール誘導体を成分化合物とする分子化合物
FR2964316B1 (fr) * 2010-09-03 2013-03-08 Thierry Rouleau Dispositif permettant d'obtenir une retraction gingivale par effet astringent et hemostatique associe a un effet de desinfection et d'auto elimination

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1518102C3 (de) * 1964-03-09 1974-02-14 Pabianickie Zaklady Farmaceutyczne Polfa Przedsiebiorstwo Panstwowe, Pabianice (Polen) Verfahren zur Herstellung eines reinen wasserlöslichen für therapeutische Zwecke geeigneten Kondensationsproduktes aus m-Kresolsulfonsäure und Formaldehyd

Also Published As

Publication number Publication date
JPS56113754A (en) 1981-09-07
DK517580A (da) 1981-06-05
EP0029990A1 (de) 1981-06-10
ZA807544B (en) 1981-11-25
PL228235A1 (es) 1982-08-02
PT72160A (en) 1981-01-01
IL61600A0 (en) 1981-01-30
IE50610B1 (en) 1986-05-28
EP0029990B1 (de) 1982-09-08
ES497410A0 (es) 1982-01-01
PT72160B (en) 1982-07-05
IE802519L (en) 1981-06-04
DE3060828D1 (en) 1982-10-28
ATE1523T1 (de) 1982-09-15
AU535714B2 (en) 1984-04-05
AU6499780A (en) 1981-06-11
NZ195716A (en) 1983-06-14
GR71617B (es) 1983-06-17
IL61600A (en) 1984-06-29

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