ES8201419A1 - Un metodo para preparar una solucion acuosa de nitrogliceri-na - Google Patents
Un metodo para preparar una solucion acuosa de nitrogliceri-naInfo
- Publication number
- ES8201419A1 ES8201419A1 ES496747A ES496747A ES8201419A1 ES 8201419 A1 ES8201419 A1 ES 8201419A1 ES 496747 A ES496747 A ES 496747A ES 496747 A ES496747 A ES 496747A ES 8201419 A1 ES8201419 A1 ES 8201419A1
- Authority
- ES
- Spain
- Prior art keywords
- nitroglycerin
- aqueous solution
- xylitol
- mannitol
- sorbitol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- SNIOPGDIGTZGOP-UHFFFAOYSA-N Nitroglycerin Chemical compound [O-][N+](=O)OCC(O[N+]([O-])=O)CO[N+]([O-])=O SNIOPGDIGTZGOP-UHFFFAOYSA-N 0.000 title abstract 3
- 239000000006 Nitroglycerin Substances 0.000 title abstract 3
- 229960003711 glyceryl trinitrate Drugs 0.000 title abstract 3
- 239000007864 aqueous solution Substances 0.000 title abstract 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
- 235000010356 sorbitol Nutrition 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000811 xylitol Substances 0.000 abstract 1
- 235000010447 xylitol Nutrition 0.000 abstract 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 abstract 1
- 229960002675 xylitol Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP54146011A JPS599539B2 (ja) | 1979-11-13 | 1979-11-13 | ニトログリセリン水溶液及びその製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES496747A0 ES496747A0 (es) | 1981-11-16 |
| ES8201419A1 true ES8201419A1 (es) | 1981-11-16 |
Family
ID=15398067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES496747A Expired ES8201419A1 (es) | 1979-11-13 | 1980-11-12 | Un metodo para preparar una solucion acuosa de nitrogliceri-na |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4323577A (en:Method) |
| JP (1) | JPS599539B2 (en:Method) |
| CA (1) | CA1163199A (en:Method) |
| DE (1) | DE3042332A1 (en:Method) |
| DK (1) | DK161186C (en:Method) |
| ES (1) | ES8201419A1 (en:Method) |
| FR (1) | FR2469178A1 (en:Method) |
| GB (1) | GB2062467B (en:Method) |
| IT (1) | IT1147022B (en:Method) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2059264A1 (es) * | 1992-11-05 | 1994-11-01 | Berrazueta Fernandez Jose Ramo | Utilizacion de los nitrovasodilatadores en la preparacion de medicamentos antiinflamatorios y analgesicos de uso topico. |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1163561A (en) * | 1979-11-06 | 1984-03-13 | Cyril Boroda | Preparation containing nitroglycerine and optionally other medicaments and preparation thereof |
| DE3109783C2 (de) * | 1981-03-13 | 1987-04-02 | Schwarz GmbH, 4019 Monheim | Verfahren zur Herstellung einer ethanolfreien Nitroglycerinlösung mit einer Konzentration von etwa 1 mg Nitroglycerin/ml |
| DE3237284A1 (de) * | 1982-10-08 | 1984-04-12 | G. Pohl-Boskamp GmbH & Co Chemisch-pharmazeutische Fabrik, 2214 Hohenlockstedt | Loesungsvermittlerfreie, waessrige nitroglycerinloesung |
| JPH0653658B2 (ja) * | 1984-12-17 | 1994-07-20 | 中外製薬株式会社 | 安定な錠剤の製造法 |
| JPH0665647B2 (ja) * | 1985-06-12 | 1994-08-24 | 株式会社三和化学研究所 | 移植皮膚処置剤 |
| KR950010150B1 (ko) * | 1986-01-14 | 1995-09-11 | 쥬우가이세이야꾸 가부시끼가이샤 | 니코란딜 함유 주사제의 안정화 방법 |
| KR940000232B1 (ko) * | 1986-01-17 | 1994-01-12 | 쥬우가이세이야꾸 가부시끼가이샤 | 니코란딜 제제의 안정화 방법 |
| US4882356A (en) * | 1987-03-10 | 1989-11-21 | Nassar Munir N | Stable injectable antiemetic compositions |
| FI871447A7 (fi) * | 1986-04-07 | 1987-10-08 | Bristol Myers Co | Stabila injicerbara antivomitiva kompositioner. |
| US4816568A (en) * | 1986-05-16 | 1989-03-28 | International Minerals & Chemical Corp. | Stabilization of growth hormones |
| US4879308A (en) * | 1987-08-11 | 1989-11-07 | Lyphomed, Inc. | Aqueous nitroglycerin injection and manufacturing process |
| US5001151A (en) * | 1987-08-11 | 1991-03-19 | Fujisawa Usa, Inc. | Aqueous nitroglycerin injection and manufacturing process |
| JPH0645538B2 (ja) * | 1987-09-30 | 1994-06-15 | 日本化薬株式会社 | ニトログリセリンスプレー剤 |
| DE4026072A1 (de) * | 1990-08-17 | 1992-02-20 | Sanol Arznei Schwarz Gmbh | Nitroglycerinhaltiger, hydrophiler, waessriger pumpspray |
| PT835098E (pt) | 1995-06-27 | 2002-12-31 | Boehringer Ingelheim Pharma | Nova composicao farmaceutica estavel para a producao de aerossois sem gas propulsante |
| JO2735B1 (en) * | 2003-01-30 | 2013-09-15 | هيلسين هيلث كير أس ايه. | Liquid pharmaceutical formations of balloonosterone |
| DE202008007318U1 (de) * | 2008-03-14 | 2008-07-31 | G. Pohl-Boskamp Gmbh & Co. Kg | Langzeitstabile pharmazeutische Zubereitung mit dem Wirkstoff Glyceroltrinitrat |
| CA2806636C (en) | 2010-08-03 | 2018-01-23 | G. Pohl-Boskamp Gmbh & Co. Kg | Use of glyceryl trinitrate for treating traumatic edema |
| EP3354259A1 (en) | 2011-02-25 | 2018-08-01 | G. Pohl-Boskamp GmbH & Co. KG | Stabilized granules containing glyceryl trinitrate |
| HUE033092T2 (hu) | 2012-05-31 | 2017-11-28 | G Pohl-Boskamp Gmbh & Co Kg | Arteriogenezis indukálása nitroglicerinnel mint nitrogén-oxid donorral |
| US9248099B2 (en) | 2012-05-31 | 2016-02-02 | Desmoid Aktiengesellschaft | Use of stabilized granules containing glyceryl trinitrate for arteriogenesis |
| EP2878310B1 (en) | 2013-11-29 | 2017-01-11 | G. Pohl-Boskamp GmbH & Co. KG | Sprayable aqueous composition comprising glyceryl trinitrate |
| CN116251057B (zh) * | 2022-12-29 | 2024-06-07 | 平光制药股份有限公司 | 一种硝酸异山梨酯注射液及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE632504A (en:Method) * | 1962-05-24 | |||
| CH513760A (it) | 1970-10-14 | 1971-10-15 | I B Anstalt | Impianto automatico di caricamento di fardelli di formato uniforme su veicoli |
| DE2301664C3 (de) | 1973-01-13 | 1979-07-12 | Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz | Oral verabreichbares, Nitroglycerin enthaltendes Arzneimittel |
| JPS5138412A (en) | 1974-09-24 | 1976-03-31 | Nippon Kayaku Kk | Kokoseizai no seiho |
-
1979
- 1979-11-13 JP JP54146011A patent/JPS599539B2/ja not_active Expired
-
1980
- 1980-11-03 US US06/203,142 patent/US4323577A/en not_active Expired - Lifetime
- 1980-11-07 GB GB8035907A patent/GB2062467B/en not_active Expired
- 1980-11-10 CA CA000364363A patent/CA1163199A/en not_active Expired
- 1980-11-10 DE DE19803042332 patent/DE3042332A1/de active Granted
- 1980-11-11 IT IT50122/80A patent/IT1147022B/it active
- 1980-11-12 FR FR8024070A patent/FR2469178A1/fr active Granted
- 1980-11-12 ES ES496747A patent/ES8201419A1/es not_active Expired
- 1980-11-12 DK DK482180A patent/DK161186C/da active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2059264A1 (es) * | 1992-11-05 | 1994-11-01 | Berrazueta Fernandez Jose Ramo | Utilizacion de los nitrovasodilatadores en la preparacion de medicamentos antiinflamatorios y analgesicos de uso topico. |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5671046A (en) | 1981-06-13 |
| DK482180A (da) | 1981-05-14 |
| DE3042332A1 (de) | 1981-05-21 |
| CA1163199A (en) | 1984-03-06 |
| FR2469178A1 (fr) | 1981-05-22 |
| DK161186B (da) | 1991-06-10 |
| US4323577A (en) | 1982-04-06 |
| DK161186C (da) | 1991-11-25 |
| JPS599539B2 (ja) | 1984-03-03 |
| ES496747A0 (es) | 1981-11-16 |
| IT1147022B (it) | 1986-11-19 |
| IT8050122A0 (it) | 1980-11-11 |
| GB2062467B (en) | 1983-07-20 |
| GB2062467A (en) | 1981-05-28 |
| FR2469178B1 (en:Method) | 1983-12-23 |
| DE3042332C2 (en:Method) | 1988-08-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970303 |