ES8201119A1 - Un procedimiento para la preparacion de derivados del acido feniloxiacetico. - Google Patents

Un procedimiento para la preparacion de derivados del acido feniloxiacetico.

Info

Publication number
ES8201119A1
ES8201119A1 ES495751A ES495751A ES8201119A1 ES 8201119 A1 ES8201119 A1 ES 8201119A1 ES 495751 A ES495751 A ES 495751A ES 495751 A ES495751 A ES 495751A ES 8201119 A1 ES8201119 A1 ES 8201119A1
Authority
ES
Spain
Prior art keywords
loweralkyl
hydrogen
hydroxyaminomethyl
phenoxy
benzoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES495751A
Other languages
English (en)
Other versions
ES495751A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of ES8201119A1 publication Critical patent/ES8201119A1/es
Publication of ES495751A0 publication Critical patent/ES495751A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DEL ACIDO FENILOXIACETICO DE FORMULA (I), DONDE R1 ES -CH2-CH2; R4 ES HIDROGENO O ALQUILO INFERIOR; R3 ES HIDROXI, ALCOXI O ADAMANTILOXI; R2 ES HIDROGENO, HALOGENO, R1, O HALOALQUILO, ALQUILO, ALCOXI O ALQUILTIO INFERIOR, N X1 Y X2 SON HIDROGENO, ALQUILO INFERIOR,HALOGENO O FORMAN UN PUENTE DE 1,3-BUTIDIENILENO, CUANDO SE ENCUENTRAN SOBRE ATOMOS DE CARBONO ADYACENTES DEL ANILLO BENCENICO. CONSISTE EN HACER REACCIONAR EL CORRESPONDIENTE ACIDO 4-(HIDROXIBENZOI) FENOXIACETICO DE FORMULA (II) CON 2-CLORO-N-(HIDROXIMETIL)ACETAMIDA, PARA FORMAR EL CORRESPONDIENTE COMPUESTO AMIDO ALQUILADO. A CONTINUACION SE SOMETE DICHO COMPUESTO A REACCION DE HIDROLISIS Y, SI SE DESEA, SE ESTERIFICA EL PRODUCTO OBTENIDO. DE PLICACION COMO AGENTES DIURETICOS PARA AUMENTAR LA EXCRECION DE ORINA.
ES495751A 1979-10-09 1980-10-08 Un procedimiento para la preparacion de derivados del acido feniloxiacetico. Granted ES495751A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8300879A 1979-10-09 1979-10-09

Publications (2)

Publication Number Publication Date
ES8201119A1 true ES8201119A1 (es) 1981-12-01
ES495751A0 ES495751A0 (es) 1981-12-01

Family

ID=22175236

Family Applications (1)

Application Number Title Priority Date Filing Date
ES495751A Granted ES495751A0 (es) 1979-10-09 1980-10-08 Un procedimiento para la preparacion de derivados del acido feniloxiacetico.

Country Status (16)

Country Link
JP (1) JPS56115746A (es)
AR (1) AR228139A1 (es)
AU (1) AU538125B2 (es)
BE (1) BE885586A (es)
CA (1) CA1149803A (es)
CH (1) CH646135A5 (es)
DE (1) DE3038011A1 (es)
ES (1) ES495751A0 (es)
FR (1) FR2467193A1 (es)
GB (1) GB2060628B (es)
GR (1) GR70775B (es)
IT (1) IT1132929B (es)
NL (1) NL8005566A (es)
PH (1) PH16254A (es)
SE (1) SE8006870L (es)
ZA (1) ZA805738B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4435422A (en) * 1982-09-15 1984-03-06 Abbott Laboratories 5-Substituted 2,3-dihydrobenzofuran-2-carboxylic acids and their use in diuretic compositions
GB2216515A (en) * 1988-03-04 1989-10-11 Nippon Shinyaku Co Ltd Acylphenol derivatives
US5883294A (en) * 1997-06-18 1999-03-16 The Regeants Of The University Of California Selective thyroid hormone analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5195049A (en) * 1975-02-12 1976-08-20 * **********so*****no***tsu*****************************************ni*no
US4058559A (en) 1975-09-24 1977-11-15 Abbott Laboratories 4-Aroyl-substituted phenoxy acetic acids

Also Published As

Publication number Publication date
GR70775B (es) 1983-03-22
CA1149803A (en) 1983-07-12
AR228139A1 (es) 1983-01-31
IT1132929B (it) 1986-07-09
BE885586A (fr) 1981-04-08
JPS56115746A (en) 1981-09-11
SE8006870L (sv) 1981-04-10
AU538125B2 (en) 1984-08-02
CH646135A5 (fr) 1984-11-15
FR2467193B1 (es) 1983-06-10
DE3038011A1 (de) 1981-04-23
AU6262680A (en) 1981-04-16
IT8025204A0 (it) 1980-10-08
ES495751A0 (es) 1981-12-01
GB2060628B (en) 1984-01-11
PH16254A (en) 1983-08-16
FR2467193A1 (fr) 1981-04-17
GB2060628A (en) 1981-05-07
NL8005566A (nl) 1981-04-13
ZA805738B (en) 1981-09-30

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