ES8200559A1 - Un anticuerpo monoclonal - Google Patents

Un anticuerpo monoclonal

Info

Publication number
ES8200559A1
ES8200559A1 ES495165A ES495165A ES8200559A1 ES 8200559 A1 ES8200559 A1 ES 8200559A1 ES 495165 A ES495165 A ES 495165A ES 495165 A ES495165 A ES 495165A ES 8200559 A1 ES8200559 A1 ES 8200559A1
Authority
ES
Spain
Prior art keywords
monoclonal antibody
cells
suppressor
preparing
human cytotoxic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES495165A
Other languages
English (en)
Other versions
ES495165A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Pharmaceutical Corp
Original Assignee
Ortho Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26758322&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8200559(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Pharmaceutical Corp filed Critical Ortho Pharmaceutical Corp
Publication of ES8200559A1 publication Critical patent/ES8200559A1/es
Publication of ES495165A0 publication Critical patent/ES495165A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

METODO DE PREPARACION DE UN ANTICUERPO MONOCLONAL. SE INMUNIZAN RATONES CON TIMOCITOS HUMANOS, SE EXTIRPAN LOS BAZOS DE LOS RATONES INMUNIZADOS Y SE PRERARA UN SUSPENSION DEL BAZO EN 1 ML. DE UN MEDIO ADECUADO. SE FUSIONAN LAS CELULAS DE BAZO EN SUSPENSION CON CELULAS DE MELINA DE RATON, MEDIANTE UN PROMOTOR DE FUSION COMO POLIETILENGICOL. SE DILUYEN Y CULTIVAN EN VASIJAS DIFERENTES LA MEZCLA DE CELULAS DE BAZO NO FUSIONADAS, CELULAS DE MIELOMA NO FUSIONADAS Y CELULAS FUSIONADAS. SE SELECCIONA, POR DILUCION LIMITANTE, EN EL LIQUIDO QUE SOBRENADA EN LAS VASIJAS, EL HIBRIDOMA QUE PRODUCE EL ANTICUERPO DESEADO. SE PRODUCE EL ANTICUERPO POR CULTIVO <IN VITRO> DEL HIBRIDOMA U OTROS METODOS. DE APLICACION EN EL TRATAMIENTO Y DIAGNOSIS DE ENFERMEDADES, CONTRA LOS ANTIGENOS ENCONTRADOS EN LAS CELULAS T CITOTOXICAS HUMANAS.
ES495165A 1979-09-18 1980-09-18 Un anticuerpo monoclonal Granted ES495165A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7664279A 1979-09-18 1979-09-18
US06/082,515 US4364932A (en) 1979-09-18 1979-10-09 Monoclonal antibody to human cytotoxic and suppressor T cells and methods of preparing same

Publications (2)

Publication Number Publication Date
ES8200559A1 true ES8200559A1 (es) 1981-11-16
ES495165A0 ES495165A0 (es) 1981-11-16

Family

ID=26758322

Family Applications (1)

Application Number Title Priority Date Filing Date
ES495165A Granted ES495165A0 (es) 1979-09-18 1980-09-18 Un anticuerpo monoclonal

Country Status (19)

Country Link
US (1) US4364932A (es)
EP (1) EP0025722B2 (es)
AU (1) AU537806B2 (es)
CA (1) CA1170593A (es)
DE (2) DE25722T1 (es)
DK (1) DK154566C (es)
ES (1) ES495165A0 (es)
FI (1) FI75364C (es)
GR (1) GR70286B (es)
HK (1) HK23986A (es)
IE (1) IE50534B1 (es)
IL (1) IL61063A (es)
MY (1) MY8600515A (es)
NO (1) NO159884C (es)
NZ (1) NZ194982A (es)
PH (1) PH16567A (es)
PT (1) PT71814B (es)
SG (1) SG6386G (es)
YU (1) YU44411B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4637983A (en) * 1979-10-09 1987-01-20 Ortho Pharmaceutical Corporation Hybrid cell line for producing monoclonal antibody to human cytotoxic and suppressor T cells, antibody, and methods
US4803262A (en) * 1979-10-09 1989-02-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing monoclonal antibody to human cytotoxic and suppressor T cells, antibody, and methods
USRE32011E (en) * 1981-12-14 1985-10-22 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4511662A (en) * 1982-06-18 1985-04-16 Bio-Rad Laboratories, Inc. Simultaneous assay for T and B lymphocyte populations and subpopulations
US4443427A (en) * 1982-06-21 1984-04-17 Sidney Farber Cancer Institute, Inc. Monoclonal antibody
US4524025A (en) * 1982-06-30 1985-06-18 E. I. Du Pont De Nemours And Company Hybridoma cell lines and monoclonal antibodies to theophylline
US4579827A (en) * 1983-03-11 1986-04-01 Sloan-Kettering Institute For Cancer Research Monoclonal antibodies to human gastrointestinal cancers and hybridoma method of production of the monoclonal antibodies
US4677056A (en) * 1983-08-18 1987-06-30 Sloan-Kettering Institute For Cancer Research Monoclonal antibody subsetting human helper and killer T-cells and method
US4965204A (en) * 1984-02-06 1990-10-23 The Johns Hopkins University Human stem cells and monoclonal antibodies
US5130144B1 (en) * 1984-02-06 1995-08-15 Univ Johns Hopkins Human stem cells and monoclonal antibodies
FR2560212B1 (fr) * 1984-02-24 1989-12-29 Unicet Anticorps monoclonaux contre l'interferon a2 et hybridomes produisant de tels anticorps
US4649106A (en) * 1984-06-01 1987-03-10 Dana-Farber Cancer Institute, Inc. Distinguishing subsets of human cells
JPS6179164A (ja) * 1984-09-26 1986-04-22 Amano Pharmaceut Co Ltd 抗原抗体反応の短縮方法
US5431897A (en) * 1985-04-19 1995-07-11 Sloan-Kettering Institute For Cancer Research Method of imaging colorectal carcinoma lesion and composition for use therein
EP0302894B1 (en) * 1986-04-28 1992-11-19 Endotronics Inc. Method of culturing leukocytes
US4970299A (en) * 1986-07-03 1990-11-13 Sloan-Kettering Institute For Cancer Research Monoclonal antibodies selective for prostate cancer
US5085985A (en) * 1987-11-12 1992-02-04 Becton Dickinson & Co. Monoclonal antibodies and their use in a method for monitoring subsets of activated T cells
US5601819A (en) * 1988-08-11 1997-02-11 The General Hospital Corporation Bispecific antibodies for selective immune regulation and for selective immune cell binding
ZA9810371B (en) * 1997-11-13 1999-08-30 Schering Corp Th2 cell depletion; compositions; methods.
CA2310805A1 (en) 1997-11-24 1999-06-03 Johnson T. Wong Methods for treatment of hiv or other infections using a t cell or viral activator and anti-retroviral combination therapy
US7653260B2 (en) 2004-06-17 2010-01-26 Carl Zeis MicroImaging GmbH System and method of registering field of view
US8582924B2 (en) 2004-06-30 2013-11-12 Carl Zeiss Microimaging Gmbh Data structure of an image storage and retrieval system

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US4172124A (en) * 1978-04-28 1979-10-23 The Wistar Institute Method of producing tumor antibodies
US4284412A (en) * 1979-07-13 1981-08-18 Ortho Diagnostics, Inc. Method and apparatus for automated identification and enumeration of specified blood cell subclasses

Also Published As

Publication number Publication date
EP0025722A3 (en) 1981-11-04
DE3070669D1 (en) 1985-06-27
PH16567A (en) 1983-11-18
IL61063A (en) 1984-04-30
FI75364C (fi) 1988-06-09
NO159884B (no) 1988-11-07
EP0025722A2 (en) 1981-03-25
DK154566C (da) 1989-04-17
AU6247680A (en) 1981-04-09
EP0025722B2 (en) 1999-04-14
YU239280A (en) 1984-04-30
IL61063A0 (en) 1980-11-30
MY8600515A (en) 1986-12-31
DK154566B (da) 1988-11-28
NO159884C (no) 1989-02-15
NZ194982A (en) 1983-02-15
ES495165A0 (es) 1981-11-16
US4364932A (en) 1982-12-21
PT71814A (en) 1980-10-01
DE25722T1 (de) 1984-07-19
PT71814B (en) 1982-03-26
IE50534B1 (en) 1986-05-14
NO802751L (no) 1981-03-19
HK23986A (en) 1986-04-11
IE801944L (en) 1981-03-18
CA1170593A (en) 1984-07-10
FI75364B (fi) 1988-02-29
FI802917A (fi) 1981-03-19
EP0025722B1 (en) 1985-05-22
SG6386G (en) 1986-11-21
AU537806B2 (en) 1984-07-12
YU44411B (en) 1990-08-31
GR70286B (es) 1982-09-03
DK394880A (da) 1981-03-19

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010820