ES8105012A1 - Procedimiento para la preparacion de derivados 17-beta de 4-diazo-5- alfa-androstan-3-onas - Google Patents
Procedimiento para la preparacion de derivados 17-beta de 4-diazo-5- alfa-androstan-3-onasInfo
- Publication number
- ES8105012A1 ES8105012A1 ES491010A ES491010A ES8105012A1 ES 8105012 A1 ES8105012 A1 ES 8105012A1 ES 491010 A ES491010 A ES 491010A ES 491010 A ES491010 A ES 491010A ES 8105012 A1 ES8105012 A1 ES 8105012A1
- Authority
- ES
- Spain
- Prior art keywords
- inhibitors
- alpha
- testosterone
- diazo
- reductase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 108010029908 3-oxo-5-alpha-steroid 4-dehydrogenase Proteins 0.000 title 1
- 102000001779 3-oxo-5-alpha-steroid 4-dehydrogenase Human genes 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- NVKAWKQGWWIWPM-ABEVXSGRSA-N 17-β-hydroxy-5-α-Androstan-3-one Chemical compound C1C(=O)CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CC[C@H]21 NVKAWKQGWWIWPM-ABEVXSGRSA-N 0.000 abstract 1
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 206010039792 Seborrhoea Diseases 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229960003473 androstanolone Drugs 0.000 abstract 1
- 230000037312 oily skin Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229960003604 testosterone Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3535779A | 1979-05-02 | 1979-05-02 | |
| US6974179A | 1979-08-27 | 1979-08-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES491010A0 ES491010A0 (es) | 1981-05-16 |
| ES8105012A1 true ES8105012A1 (es) | 1981-05-16 |
Family
ID=26712031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES491010A Expired ES8105012A1 (es) | 1979-05-02 | 1980-04-29 | Procedimiento para la preparacion de derivados 17-beta de 4-diazo-5- alfa-androstan-3-onas |
Country Status (16)
| Country | Link |
|---|---|
| AT (1) | AT390794B (enExample) |
| AU (1) | AU532558B2 (enExample) |
| CA (1) | CA1154008A (enExample) |
| CH (1) | CH643863A5 (enExample) |
| DE (1) | DE3017015A1 (enExample) |
| DK (1) | DK166501B1 (enExample) |
| ES (1) | ES8105012A1 (enExample) |
| FR (1) | FR2455610A1 (enExample) |
| GB (1) | GB2048888B (enExample) |
| IE (1) | IE49704B1 (enExample) |
| IL (1) | IL59934A (enExample) |
| IT (1) | IT1188932B (enExample) |
| NL (1) | NL191387C (enExample) |
| NO (1) | NO154884C (enExample) |
| NZ (1) | NZ193527A (enExample) |
| SE (1) | SE448097B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8503940D0 (en) * | 1985-02-15 | 1985-03-20 | Erba Farmitalia | 4-substituted androstendione derivatives |
| AU642757B2 (en) * | 1990-08-01 | 1993-10-28 | Merrell Dow Pharmaceuticals Inc. | 4-amino-delta4, 6-steroids and their use as 5alpha-reductase inhibitors |
| US5143909A (en) * | 1991-03-19 | 1992-09-01 | Merrell Dow Pharmaceuticals Inc. | Aminosteroids in a method for inhibiting c17-20 lyase |
| NZ239142A (en) * | 1990-08-01 | 1994-05-26 | Merrell Dow Pharma | 4-amino-delta-4-steroids; preparatory processes and pharmaceutical compositions |
| EP0794456B1 (en) | 1996-03-07 | 2003-01-29 | Agfa-Gevaert | Method of reproducing an electronically stored medical image on a light-sensitive photographic material |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3917829A (en) * | 1971-11-08 | 1975-11-04 | Research Corp | Novel methods of inhibiting the activity of testosterone 5{60 -reductase |
| US4088760A (en) * | 1976-06-23 | 1978-05-09 | Richardson-Merrell Inc. | Testosterone 5α-reductase inhibitors |
-
1980
- 1980-04-21 CA CA000350283A patent/CA1154008A/en not_active Expired
- 1980-04-22 IE IE806/80A patent/IE49704B1/en not_active IP Right Cessation
- 1980-04-23 AU AU57747/80A patent/AU532558B2/en not_active Expired
- 1980-04-24 NZ NZ193527A patent/NZ193527A/xx unknown
- 1980-04-25 GB GB8013775A patent/GB2048888B/en not_active Expired
- 1980-04-28 IL IL59934A patent/IL59934A/xx unknown
- 1980-04-29 SE SE8003242A patent/SE448097B/sv not_active IP Right Cessation
- 1980-04-29 ES ES491010A patent/ES8105012A1/es not_active Expired
- 1980-04-30 CH CH335980A patent/CH643863A5/de not_active IP Right Cessation
- 1980-04-30 NO NO801254A patent/NO154884C/no unknown
- 1980-04-30 FR FR8009848A patent/FR2455610A1/fr active Granted
- 1980-04-30 AT AT0232880A patent/AT390794B/de not_active IP Right Cessation
- 1980-04-30 IT IT48559/80A patent/IT1188932B/it active
- 1980-05-01 DK DK194180A patent/DK166501B1/da not_active IP Right Cessation
- 1980-05-01 NL NL8002529A patent/NL191387C/xx not_active IP Right Cessation
- 1980-05-02 DE DE19803017015 patent/DE3017015A1/de active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DK166501B1 (da) | 1993-06-01 |
| IL59934A0 (en) | 1980-06-30 |
| DK194180A (da) | 1980-11-03 |
| NL8002529A (nl) | 1980-11-04 |
| GB2048888B (en) | 1983-05-25 |
| NL191387C (nl) | 1995-07-03 |
| ATA232880A (de) | 1989-12-15 |
| IT8048559A1 (it) | 1981-10-30 |
| FR2455610B1 (enExample) | 1982-04-30 |
| AU5774780A (en) | 1980-11-06 |
| IT8048559A0 (it) | 1980-04-30 |
| IT1188932B (it) | 1988-01-28 |
| IL59934A (en) | 1983-06-15 |
| NL191387B (nl) | 1995-02-01 |
| NO154884B (no) | 1986-09-29 |
| DE3017015C2 (enExample) | 1989-04-20 |
| AT390794B (de) | 1990-06-25 |
| AU532558B2 (en) | 1983-10-06 |
| IE800806L (en) | 1980-11-02 |
| GB2048888A (en) | 1980-12-17 |
| ES491010A0 (es) | 1981-05-16 |
| CA1154008A (en) | 1983-09-20 |
| SE448097B (sv) | 1987-01-19 |
| FR2455610A1 (fr) | 1980-11-28 |
| NO154884C (no) | 1987-01-07 |
| NZ193527A (en) | 1984-10-19 |
| IE49704B1 (en) | 1985-11-27 |
| DE3017015A1 (de) | 1980-11-20 |
| NO801254L (no) | 1980-11-03 |
| CH643863A5 (de) | 1984-06-29 |
| SE8003242L (sv) | 1980-11-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20020304 |