ES8102702A1 - Proceso para la preparacion de tabletas farmaceuticas o medicinales de administracion oral, con liberacion retardada delagente activo, en tabletas en las que la cantidad de libera-cion del agente activo es predeterminada. - Google Patents
Proceso para la preparacion de tabletas farmaceuticas o medicinales de administracion oral, con liberacion retardada delagente activo, en tabletas en las que la cantidad de libera-cion del agente activo es predeterminada.Info
- Publication number
- ES8102702A1 ES8102702A1 ES488168A ES488168A ES8102702A1 ES 8102702 A1 ES8102702 A1 ES 8102702A1 ES 488168 A ES488168 A ES 488168A ES 488168 A ES488168 A ES 488168A ES 8102702 A1 ES8102702 A1 ES 8102702A1
- Authority
- ES
- Spain
- Prior art keywords
- tablets
- liberation
- active agent
- preparation
- matrix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE TABLETAS MEDICINALES CON LIBERACION RETARDADA DEL AGENTE ACTIVO.CONSISTE EN AJUSTAR LA VELOCIDAD DE LIBERACION DEL MEDICAMENTO O AGENTE ACTIVO, DURANTE EL PROCESODE GRANULACION, MEDIANTE EL EMPLEO DE PLASTICOS DE POLIMETACRILATO INSOLUBLES EN AGUA NEUTRA O LIGERAMENTE ACIDA, Y LA INTRODUCCION DE UN ESTER DE ACIDO GRASO, ANTES DE QUE SE COMPRIMAN LAS TABLETAS. COMO SUSTANCIAS MATRICES RETARDANTES SE EMPLEAN: COPOLOMERIZADO DE ACIDO ACRILICO Y METACRILICO O DE METACRILICO Y ESTER DE METILO DEL MISMO, CON CARACTER ANIONICO; COPOLIMERIZADO DE METILO Y ESTERES DE ETILO DE ACIDO ACRILICO Y METACRILICO; ACEITE DE CASTOR O RICINO HIDROGENADO O ACEITE DE SEMILLAS DE ALGODON HIDROGENADO. EL AGENTE REGULADOR ENTRA EN LA PROPORCION DE MENOS DEL 15 POR 100 DEL PESO BRUTO DE LA TABLETA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI790350A FI63335B (fi) | 1979-02-02 | 1979-02-02 | Foerfarande foer framstaellning av tabletter med foerdroejd loslighet av effektaemne |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8102702A1 true ES8102702A1 (es) | 1981-02-16 |
ES488168A0 ES488168A0 (es) | 1981-02-16 |
Family
ID=8512353
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES488168A Granted ES488168A0 (es) | 1979-02-02 | 1980-02-01 | Proceso para la preparacion de tabletas farmaceuticas o medicinales de administracion oral, con liberacion retardada delagente activo, en tabletas en las que la cantidad de libera-cion del agente activo es predeterminada. |
Country Status (15)
Country | Link |
---|---|
US (1) | US4351825A (es) |
EP (1) | EP0014514B1 (es) |
JP (1) | JPS55129222A (es) |
AR (1) | AR222207A1 (es) |
AT (1) | ATE20182T1 (es) |
CA (1) | CA1144071A (es) |
DE (1) | DE3071625D1 (es) |
DK (1) | DK28480A (es) |
ES (1) | ES488168A0 (es) |
FI (1) | FI63335B (es) |
GR (1) | GR65623B (es) |
IE (1) | IE51741B1 (es) |
NO (1) | NO149490B (es) |
PT (1) | PT70719A (es) |
ZA (1) | ZA80553B (es) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1168014B (it) * | 1981-08-05 | 1987-05-20 | Erba Farmitalia | Forme farmaceutiche a cessione protratta |
DE3314003A1 (de) * | 1983-04-18 | 1984-10-18 | Boehringer Ingelheim KG, 6507 Ingelheim | Teilbare tablette mit verzoegerter wirkstofffreigabe und verfahren zu deren herstellung |
HU190619B (en) * | 1983-11-11 | 1986-09-29 | Bezzegh,Denes,Hu | Process for producing tablets with controlled dissolution of active ingredients |
FR2556965B1 (fr) * | 1983-12-21 | 1986-08-22 | Rhone Poulenc Sante | Nouvelle forme galenique du ketoprofene a liberation controlee |
US4927633A (en) * | 1984-03-19 | 1990-05-22 | Alza Corporation | Dispenser for delivering drug to livestock |
US4624945A (en) * | 1984-03-19 | 1986-11-25 | Alza Corporation | Dispensing system with means for increasing delivery of beneficial agent from the system |
US4729793A (en) * | 1985-08-09 | 1988-03-08 | Alza Corporation | Composition for manufacturing wall of dispensing device |
US4844984A (en) * | 1984-03-19 | 1989-07-04 | Alza Corporation | Dispensing system with means for increasing delivery of beneficial agent from the system |
US5000957A (en) * | 1984-03-19 | 1991-03-19 | Alza Corporation | Dispenser comprising hydrophilic osmopolymer |
US4684524A (en) * | 1984-03-19 | 1987-08-04 | Alza Corporation | Rate controlled dispenser for administering beneficial agent |
US4629621A (en) * | 1984-07-23 | 1986-12-16 | Zetachron, Inc. | Erodible matrix for sustained release bioactive composition |
FR2573307B1 (fr) * | 1984-11-22 | 1988-06-10 | Virbac Ctre Rech Biolog | Implants anabolisants a liberation prolongee |
DE3524003A1 (de) * | 1985-07-04 | 1987-01-08 | Heumann Ludwig & Co Gmbh | Arzneimittelgranulat mit verzoegerter wirkstofffreisetzung und verfahren zu seiner herstellung |
GB2186485B (en) * | 1986-02-13 | 1988-09-07 | Ethical Pharma Ltd | Slow release formulation |
IT1204294B (it) * | 1986-03-11 | 1989-03-01 | Gentili Ist Spa | Metodo di fabbricazione di granulari atti a produzione di compresse rivestite,per uso orale,a rilascio controllato |
US5624683A (en) * | 1986-08-06 | 1997-04-29 | Eisai Co., Ltd. | Sustained-release multi-granule tablet |
EP0406315B1 (en) * | 1988-03-24 | 1992-11-11 | Bukh Meditec A/S | Controlled release composition |
US6056992A (en) * | 1988-06-02 | 2000-05-02 | Campbell Soup Company | Encapsulated additives |
US5268182A (en) * | 1988-06-24 | 1993-12-07 | Abbott Laboratories | Sustained-release drug dosage units of terazosin |
US5169642A (en) * | 1988-06-24 | 1992-12-08 | Abbott Laboratories | Sustained-release drug dosage units |
PH26730A (en) * | 1988-12-30 | 1992-09-28 | Ciba Geigy Ag | Coated adhesive tablets |
US4970081A (en) * | 1989-01-03 | 1990-11-13 | Sterling Drug Inc. | Controlled-release, low-dose aspirin formulation and method of treating vascular occlusive disease therewith |
IL96311A (en) † | 1989-12-01 | 1995-05-26 | Abbott Lab | Medications with delayed release |
GB9015822D0 (en) * | 1990-07-18 | 1990-09-05 | Beecham Group Plc | Compositions |
US5266331A (en) * | 1991-11-27 | 1993-11-30 | Euroceltique, S.A. | Controlled release oxycodone compositions |
US20080075781A1 (en) * | 1992-11-25 | 2008-03-27 | Purdue Pharma Lp | Controlled release oxycodone compositions |
US20070275062A1 (en) * | 1993-06-18 | 2007-11-29 | Benjamin Oshlack | Controlled release oxycodone compositions |
US5431630A (en) * | 1993-09-07 | 1995-07-11 | Surgic-Acid, Inc. | Needle guard and nonreusable syringe |
US6103262A (en) * | 1994-01-27 | 2000-08-15 | G. D. Searle & Company | Modified-release metronidazole compositions and methods for making and using same |
US5484608A (en) * | 1994-03-28 | 1996-01-16 | Pharmavene, Inc. | Sustained-release drug delivery system |
GB9522403D0 (en) * | 1995-11-01 | 1996-01-03 | Hoechst Roussel Ltd | Intravaginal drug delivery device |
US6776996B2 (en) | 1997-07-09 | 2004-08-17 | Basf Aktiengesellschaft | Pesticidal matrices |
ID20839A (id) * | 1997-07-09 | 1999-03-11 | American Cyanamid Co | Bahan acuan pestisida berlapis lebih baik, pengolahan pada pembuatannya serta komposisi-komposisi yang terkandung di dalamnya |
FR2775188B1 (fr) * | 1998-02-23 | 2001-03-09 | Lipha | Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption |
CN1203846C (zh) | 1998-03-19 | 2005-06-01 | 布里斯托尔-迈尔斯斯奎布公司 | 高溶解性药物的双相控释递送系统和方法 |
US6099859A (en) | 1998-03-20 | 2000-08-08 | Andrx Pharmaceuticals, Inc. | Controlled release oral tablet having a unitary core |
EP1949890A3 (en) | 1999-06-04 | 2011-05-18 | ALZA Corporation | Implantable gel compositions and method of manufacture |
HUP0201626A3 (en) * | 1999-06-04 | 2004-05-28 | Alza Corp Mountain View | Implantable gel compositions and method of manufacture |
US6676966B1 (en) | 2000-05-09 | 2004-01-13 | Intellipharmaceutics Corp. | Extended release metformin hydrochloride formulations |
GB0102342D0 (en) * | 2001-01-30 | 2001-03-14 | Smithkline Beecham Plc | Pharmaceutical formulation |
US20050175687A1 (en) * | 2001-01-30 | 2005-08-11 | Mcallister Stephen M. | Pharmaceutical formulations |
US7883721B2 (en) | 2001-01-30 | 2011-02-08 | Smithkline Beecham Limited | Pharmaceutical formulation |
UA81224C2 (uk) * | 2001-05-02 | 2007-12-25 | Euro Celtic S A | Дозована форма оксикодону та її застосування |
DE10127134A1 (de) * | 2001-06-05 | 2002-12-12 | Roehm Gmbh | verfahren zur Herstellung von Formkörpern aus (Meth)acrylat-Copolymeren mittels Spritzguß |
WO2003105809A1 (en) | 2002-06-17 | 2003-12-24 | Themis Laboratories Private Limited | Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them |
EP1549296A4 (en) * | 2002-08-02 | 2006-08-09 | Penwest Pharmaceuticals Co | METFORMIN FORMULATIONS WITH DELAYED RELEASE |
US20040086566A1 (en) * | 2002-11-04 | 2004-05-06 | Alpharma, Inc. | Waxy matrix dosage forms |
US7135436B2 (en) * | 2003-05-05 | 2006-11-14 | J.F. Daley International, Ltd. | Solid algicide, preparation and usage in recirculating water |
PE20060003A1 (es) | 2004-03-12 | 2006-03-01 | Smithkline Beecham Plc | Formulacion farmaceutica polimerica para moldear por inyeccion |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2987445A (en) * | 1958-10-10 | 1961-06-06 | Rohm & Haas | Drug composition |
US3062720A (en) * | 1959-05-20 | 1962-11-06 | Philips Roxane | Sustained release pharmaceutical tablet |
US3148124A (en) * | 1962-06-12 | 1964-09-08 | William E Gaunt | Method of preparing sustained release pharmaceutical tablets |
CH415963A (de) * | 1964-09-04 | 1966-06-30 | Wander Ag Dr A | Masse zur Herstellung von Tabletten mit protrahierter Wirkung |
US3577512A (en) * | 1968-10-11 | 1971-05-04 | Nat Patent Dev Corp | Sustained release tablets |
SE353229B (es) * | 1970-06-04 | 1973-01-29 | Haessle Ab | |
GB1500300A (en) * | 1975-01-06 | 1978-02-08 | Ciba Geigy Ag | Pharmaceutical preparation for the treatment of circulatory disorders |
JPS6191314A (ja) * | 1984-10-12 | 1986-05-09 | Nippon Kokan Kk <Nkk> | 取鍋精錬炉による溶鋼の精錬方法 |
-
1979
- 1979-02-02 FI FI790350A patent/FI63335B/fi not_active Application Discontinuation
- 1979-12-27 NO NO794290A patent/NO149490B/no unknown
-
1980
- 1980-01-02 DE DE8080300008T patent/DE3071625D1/de not_active Expired
- 1980-01-02 AT AT80300008T patent/ATE20182T1/de not_active IP Right Cessation
- 1980-01-02 EP EP80300008A patent/EP0014514B1/en not_active Expired
- 1980-01-14 US US06/111,962 patent/US4351825A/en not_active Expired - Lifetime
- 1980-01-23 PT PT70719A patent/PT70719A/pt active IP Right Revival
- 1980-01-23 DK DK28480A patent/DK28480A/da not_active Application Discontinuation
- 1980-01-24 JP JP641580A patent/JPS55129222A/ja active Pending
- 1980-01-28 CA CA000344502A patent/CA1144071A/en not_active Expired
- 1980-01-30 ZA ZA00800553A patent/ZA80553B/xx unknown
- 1980-01-31 GR GR61091A patent/GR65623B/el unknown
- 1980-02-01 IE IE202/80A patent/IE51741B1/en not_active IP Right Cessation
- 1980-02-01 ES ES488168A patent/ES488168A0/es active Granted
- 1980-12-30 AR AR279792A patent/AR222207A1/es active
Also Published As
Publication number | Publication date |
---|---|
NO794290L (no) | 1980-08-05 |
AR222207A1 (es) | 1981-04-30 |
CA1144071A (en) | 1983-04-05 |
ATE20182T1 (de) | 1986-06-15 |
FI790350A (fi) | 1980-08-03 |
EP0014514A2 (en) | 1980-08-20 |
PT70719A (en) | 1980-02-01 |
GR65623B (en) | 1980-10-15 |
DK28480A (da) | 1980-08-03 |
ES488168A0 (es) | 1981-02-16 |
US4351825A (en) | 1982-09-28 |
EP0014514B1 (en) | 1986-06-04 |
DE3071625D1 (en) | 1986-07-10 |
JPS55129222A (en) | 1980-10-06 |
IE51741B1 (en) | 1987-03-18 |
FI63335B (fi) | 1983-02-28 |
EP0014514A3 (en) | 1981-06-10 |
ZA80553B (en) | 1981-02-25 |
IE800202L (en) | 1980-08-02 |
NO149490B (no) | 1984-01-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20010217 |