ES548238A0 - Procedimiento para preparar analogos de adenosinas n6 susti-tuidas - Google Patents
Procedimiento para preparar analogos de adenosinas n6 susti-tuidasInfo
- Publication number
- ES548238A0 ES548238A0 ES548238A ES548238A ES548238A0 ES 548238 A0 ES548238 A0 ES 548238A0 ES 548238 A ES548238 A ES 548238A ES 548238 A ES548238 A ES 548238A ES 548238 A0 ES548238 A0 ES 548238A0
- Authority
- ES
- Spain
- Prior art keywords
- tuidas
- susti
- adenosins
- procedure
- preparing analogs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66523284A | 1984-10-26 | 1984-10-26 | |
US66523384A | 1984-10-26 | 1984-10-26 | |
US66521784A | 1984-10-26 | 1984-10-26 | |
US77231585A | 1985-09-06 | 1985-09-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES548238A0 true ES548238A0 (es) | 1986-12-01 |
ES8701774A1 ES8701774A1 (es) | 1986-12-01 |
Family
ID=27505316
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES548238A Expired ES8701774A1 (es) | 1984-10-26 | 1985-10-25 | Procedimiento para preparar analogos de adenosinas n6 susti-tuidas |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0181129B1 (es) |
KR (1) | KR910002226B1 (es) |
CN (1) | CN1013448B (es) |
AU (1) | AU575438B2 (es) |
CA (1) | CA1260931A (es) |
DE (1) | DE3568582D1 (es) |
DK (1) | DK488485A (es) |
ES (1) | ES8701774A1 (es) |
FI (1) | FI81587C (es) |
GR (1) | GR852583B (es) |
NO (1) | NO165495C (es) |
NZ (1) | NZ213971A (es) |
PT (1) | PT81373B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0206497B1 (en) * | 1985-05-15 | 1994-07-20 | The Wellcome Foundation Limited | Therapeutic nucleosides and their preparation |
WO1988003147A1 (en) * | 1986-10-31 | 1988-05-05 | Warner-Lambert Company | Selected n6-substituted adenosines having selective a2 binding activity |
GB2226027B (en) * | 1988-12-13 | 1992-05-20 | Sandoz Ltd | Adenosine derivatives,their production and use |
JPH0725785B2 (ja) * | 1989-01-11 | 1995-03-22 | 日本臓器製薬株式会社 | アデノシン誘導体及び該化合物を有効成分として含有する医薬組成物 |
ZA902280B (en) * | 1989-03-29 | 1990-12-28 | Merrell Dow Pharma | Selective adenosine receptor agents |
EP0550631B1 (en) * | 1990-09-25 | 1997-01-02 | Rhone-Poulenc Rorer International (Holdings) Inc. | Compounds having antihypertensive and anti-ischemic properties |
US5561134A (en) * | 1990-09-25 | 1996-10-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
US5705491A (en) * | 1992-10-27 | 1998-01-06 | Nippon Zoki Pharmaceutical Co., Ltd. | Adenosine deaminase inhibitor |
US5589467A (en) * | 1993-09-17 | 1996-12-31 | Novo Nordisk A/S | 2,5',N6-trisubstituted adenosine derivatives |
CN1168138A (zh) * | 1995-11-14 | 1997-12-17 | 法玛西雅厄普约翰公司 | 芳基和杂芳基嘌呤化合物 |
TW528755B (en) | 1996-12-24 | 2003-04-21 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
YU44900A (sh) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola |
HUP0103025A3 (en) | 1998-06-23 | 2002-04-29 | Glaxo Group Ltd | A2a agonist 2-(purin-9-yl)tetrahydrofuran-3,4-diol derivatives, medicaments containing the same, process for producing them and the useful intermediates |
JP3619017B2 (ja) | 1998-06-24 | 2005-02-09 | 日本臓器製薬株式会社 | 新規アラビノシルアデニン誘導体 |
US6946449B2 (en) | 2001-07-13 | 2005-09-20 | Cv Therapeutics, Inc. | Partial and full agonists of A1 adenosine receptors |
US7713946B2 (en) | 2002-07-11 | 2010-05-11 | Cv Therapeutics, Inc. | Partial and full agonists A1 adenosine receptors |
US7157440B2 (en) | 2001-07-13 | 2007-01-02 | Cv Therapeutics, Inc. | Partial and full agonists of A1 adenosine receptors |
US7265111B2 (en) | 2002-06-27 | 2007-09-04 | Sanofi-Aventis Deutschland Gmbh | Adenosine analogues and their use as pharmaceutical agents |
EP1375508A1 (en) * | 2002-06-27 | 2004-01-02 | Aventis Pharma Deutschland GmbH | N6-substituted adenosine analogues and their use as pharmaceutical agents |
EP1590359A2 (en) | 2003-02-03 | 2005-11-02 | CV Therapeutics Inc. | PARTIAL AND FULL AGONISTS OF A sb 1 /sb ADENOSINE RECEPTORS |
AR049384A1 (es) | 2004-05-24 | 2006-07-26 | Glaxo Group Ltd | Derivados de purina |
GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1545645A1 (de) * | 1965-12-06 | 1969-08-21 | Boehringer Mannheim Gmbh | Verfahren zur Herstellung von disubstituierten Adenosin-Derivaten |
DE1670077C3 (de) * | 1966-05-07 | 1975-04-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | Adenosin-Derivate und Verfahren zu ihrer Herstellung |
SE361760B (es) * | 1972-04-05 | 1973-11-12 | Haldex Ab | |
DE2230160A1 (de) * | 1972-06-21 | 1974-01-31 | Merck Patent Gmbh | Adenosinderivat |
US4373097A (en) * | 1981-04-27 | 1983-02-08 | Bioresearch S.R.L. | Process for preparing adenosine derivatives of anti-inflammatory and analgesic activity |
DE3576344D1 (de) * | 1984-04-18 | 1990-04-12 | Whitby Research Inc | Cardio-vasodilatatore n-6-substituierte adenosine. |
US5310731A (en) * | 1984-06-28 | 1994-05-10 | Whitby Research, Inc. | N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents |
CA1255297A (en) * | 1984-10-26 | 1989-06-06 | Bharat Trivedi | N.sup.6-benzopyrano and benzothiopyrano adenosines |
-
1985
- 1985-10-21 AU AU48888/85A patent/AU575438B2/en not_active Ceased
- 1985-10-23 FI FI854153A patent/FI81587C/fi not_active IP Right Cessation
- 1985-10-24 DK DK488485A patent/DK488485A/da not_active Application Discontinuation
- 1985-10-25 EP EP85307717A patent/EP0181129B1/en not_active Expired
- 1985-10-25 NO NO854278A patent/NO165495C/no unknown
- 1985-10-25 GR GR852583A patent/GR852583B/el unknown
- 1985-10-25 ES ES548238A patent/ES8701774A1/es not_active Expired
- 1985-10-25 DE DE8585307717T patent/DE3568582D1/de not_active Expired
- 1985-10-25 CA CA000493849A patent/CA1260931A/en not_active Expired
- 1985-10-25 PT PT81373A patent/PT81373B/pt not_active IP Right Cessation
- 1985-10-25 NZ NZ213971A patent/NZ213971A/en unknown
- 1985-10-26 CN CN85108658A patent/CN1013448B/zh not_active Expired
- 1985-10-26 KR KR1019850007937A patent/KR910002226B1/ko active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
PT81373A (en) | 1985-11-01 |
FI854153A0 (fi) | 1985-10-23 |
PT81373B (pt) | 1987-11-11 |
NZ213971A (en) | 1988-03-30 |
DE3568582D1 (en) | 1989-04-13 |
NO165495C (no) | 1991-02-20 |
GR852583B (es) | 1986-02-26 |
FI81587C (fi) | 1990-11-12 |
NO165495B (no) | 1990-11-12 |
EP0181129A3 (en) | 1987-05-13 |
FI81587B (fi) | 1990-07-31 |
ES8701774A1 (es) | 1986-12-01 |
KR910002226B1 (ko) | 1991-04-08 |
CA1260931A (en) | 1989-09-26 |
KR860003256A (ko) | 1986-05-21 |
DK488485A (da) | 1986-04-27 |
DK488485D0 (da) | 1985-10-24 |
FI854153L (fi) | 1986-04-27 |
EP0181129B1 (en) | 1989-03-08 |
NO854278L (no) | 1986-04-28 |
CN85108658A (zh) | 1986-07-16 |
AU4888885A (en) | 1986-05-08 |
CN1013448B (zh) | 1991-08-07 |
EP0181129A2 (en) | 1986-05-14 |
AU575438B2 (en) | 1988-07-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19960603 |