DK488485A - N6- substituerede deoxyriboseanaloger af adenosinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende saadanne forbindelser - Google Patents

N6- substituerede deoxyriboseanaloger af adenosinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende saadanne forbindelser Download PDF

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Publication number
DK488485A
DK488485A DK488485A DK488485A DK488485A DK 488485 A DK488485 A DK 488485A DK 488485 A DK488485 A DK 488485A DK 488485 A DK488485 A DK 488485A DK 488485 A DK488485 A DK 488485A
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DK
Denmark
Prior art keywords
compounds
adenosin
analysis
preparation
pharmaceutical preparations
Prior art date
Application number
DK488485A
Other languages
Danish (da)
English (en)
Other versions
DK488485D0 (da
Inventor
Harriet W Hamilton
James A Bristol
Walter Moos
Bharat K Trivedi
Michael Taylor
William C Patt
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK488485D0 publication Critical patent/DK488485D0/da
Publication of DK488485A publication Critical patent/DK488485A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK488485A 1984-10-26 1985-10-24 N6- substituerede deoxyriboseanaloger af adenosinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende saadanne forbindelser DK488485A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66521784A 1984-10-26 1984-10-26
US66523384A 1984-10-26 1984-10-26
US66523284A 1984-10-26 1984-10-26
US77231585A 1985-09-06 1985-09-06

Publications (2)

Publication Number Publication Date
DK488485D0 DK488485D0 (da) 1985-10-24
DK488485A true DK488485A (da) 1986-04-27

Family

ID=27505316

Family Applications (1)

Application Number Title Priority Date Filing Date
DK488485A DK488485A (da) 1984-10-26 1985-10-24 N6- substituerede deoxyriboseanaloger af adenosinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende saadanne forbindelser

Country Status (13)

Country Link
EP (1) EP0181129B1 (es)
KR (1) KR910002226B1 (es)
CN (1) CN1013448B (es)
AU (1) AU575438B2 (es)
CA (1) CA1260931A (es)
DE (1) DE3568582D1 (es)
DK (1) DK488485A (es)
ES (1) ES8701774A1 (es)
FI (1) FI81587C (es)
GR (1) GR852583B (es)
NO (1) NO165495C (es)
NZ (1) NZ213971A (es)
PT (1) PT81373B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK224286A (da) * 1985-05-15 1986-11-16 Wellcome Found 2',3'-dideoxy-nucleosider
WO1988003147A1 (en) * 1986-10-31 1988-05-05 Warner-Lambert Company Selected n6-substituted adenosines having selective a2 binding activity
GB2226027B (en) * 1988-12-13 1992-05-20 Sandoz Ltd Adenosine derivatives,their production and use
JPH0725785B2 (ja) * 1989-01-11 1995-03-22 日本臓器製薬株式会社 アデノシン誘導体及び該化合物を有効成分として含有する医薬組成物
ZA902280B (en) * 1989-03-29 1990-12-28 Merrell Dow Pharma Selective adenosine receptor agents
ES2095960T3 (es) * 1990-09-25 1997-03-01 Rhone Poulenc Rorer Int Compuestos que tienen propiedades antihipertensivas y antiisquemicas.
US5561134A (en) * 1990-09-25 1996-10-01 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties
EP0601322A3 (en) * 1992-10-27 1994-10-12 Nippon Zoki Pharmaceutical Co Adenosine deaminase inhibitor.
US5589467A (en) * 1993-09-17 1996-12-31 Novo Nordisk A/S 2,5',N6-trisubstituted adenosine derivatives
WO1997018212A1 (en) * 1995-11-14 1997-05-22 Pharmacia & Upjohn S.P.A. Aryl and heteroaryl purine compounds
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
DE69910213T2 (de) 1998-06-23 2004-07-01 Glaxo Group Ltd., Greenford 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivate
JP3619017B2 (ja) 1998-06-24 2005-02-09 日本臓器製薬株式会社 新規アラビノシルアデニン誘導体
US6946449B2 (en) 2001-07-13 2005-09-20 Cv Therapeutics, Inc. Partial and full agonists of A1 adenosine receptors
US7713946B2 (en) 2002-07-11 2010-05-11 Cv Therapeutics, Inc. Partial and full agonists A1 adenosine receptors
US7157440B2 (en) 2001-07-13 2007-01-02 Cv Therapeutics, Inc. Partial and full agonists of A1 adenosine receptors
US7265111B2 (en) 2002-06-27 2007-09-04 Sanofi-Aventis Deutschland Gmbh Adenosine analogues and their use as pharmaceutical agents
EP1375508A1 (en) * 2002-06-27 2004-01-02 Aventis Pharma Deutschland GmbH N6-substituted adenosine analogues and their use as pharmaceutical agents
CA2515068A1 (en) 2003-02-03 2004-08-19 Cv Therapeutics Inc. Partial and full agonists of a1 adenosine receptors
AR049384A1 (es) 2004-05-24 2006-07-26 Glaxo Group Ltd Derivados de purina
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1545645A1 (de) * 1965-12-06 1969-08-21 Boehringer Mannheim Gmbh Verfahren zur Herstellung von disubstituierten Adenosin-Derivaten
DE1670077C3 (de) * 1966-05-07 1975-04-24 Boehringer Mannheim Gmbh, 6800 Mannheim Adenosin-Derivate und Verfahren zu ihrer Herstellung
SE361760B (es) * 1972-04-05 1973-11-12 Haldex Ab
DE2230160A1 (de) * 1972-06-21 1974-01-31 Merck Patent Gmbh Adenosinderivat
US4373097A (en) * 1981-04-27 1983-02-08 Bioresearch S.R.L. Process for preparing adenosine derivatives of anti-inflammatory and analgesic activity
EP0300144A3 (en) * 1984-04-18 1989-09-27 Whitby Research Incorporated N-6 alkyl substituted adenosine derivatives as cardiac vasodilators
US5310731A (en) * 1984-06-28 1994-05-10 Whitby Research, Inc. N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents
CA1255297A (en) * 1984-10-26 1989-06-06 Bharat Trivedi N.sup.6-benzopyrano and benzothiopyrano adenosines

Also Published As

Publication number Publication date
ES8701774A1 (es) 1986-12-01
NO165495C (no) 1991-02-20
KR910002226B1 (ko) 1991-04-08
CA1260931A (en) 1989-09-26
NZ213971A (en) 1988-03-30
CN85108658A (zh) 1986-07-16
CN1013448B (zh) 1991-08-07
NO165495B (no) 1990-11-12
EP0181129A3 (en) 1987-05-13
FI854153A0 (fi) 1985-10-23
FI81587B (fi) 1990-07-31
FI81587C (fi) 1990-11-12
GR852583B (es) 1986-02-26
EP0181129B1 (en) 1989-03-08
AU575438B2 (en) 1988-07-28
DE3568582D1 (en) 1989-04-13
PT81373A (en) 1985-11-01
EP0181129A2 (en) 1986-05-14
AU4888885A (en) 1986-05-08
NO854278L (no) 1986-04-28
ES548238A0 (es) 1986-12-01
KR860003256A (ko) 1986-05-21
FI854153L (fi) 1986-04-27
DK488485D0 (da) 1985-10-24
PT81373B (pt) 1987-11-11

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