ES547950A0 - Perfeccionamientos en los aparatos para llevar a cabo secuencias reaccionales quimicas para la sintesis de polineucleotidos y otras moleculas de polimero. - Google Patents

Perfeccionamientos en los aparatos para llevar a cabo secuencias reaccionales quimicas para la sintesis de polineucleotidos y otras moleculas de polimero.

Info

Publication number
ES547950A0
ES547950A0 ES547950A ES547950A ES547950A0 ES 547950 A0 ES547950 A0 ES 547950A0 ES 547950 A ES547950 A ES 547950A ES 547950 A ES547950 A ES 547950A ES 547950 A0 ES547950 A0 ES 547950A0
Authority
ES
Spain
Prior art keywords
discs
bores
reaction
another
reaction chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES547950A
Other languages
English (en)
Other versions
ES8705352A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4286104&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES547950(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES547950A0 publication Critical patent/ES547950A0/es
Publication of ES8705352A1 publication Critical patent/ES8705352A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00324—Reactor vessels in a multiple arrangement the reactor vessels or wells being arranged in plates moving in parallel to each other
    • B01J2219/00326—Movement by rotation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00479—Means for mixing reactants or products in the reaction vessels
    • B01J2219/00488—Means for mixing reactants or products in the reaction vessels by rotation of the reaction vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/0059—Sequential processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Detergent Compositions (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Electrotherapy Devices (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Dram (AREA)
  • Steering Control In Accordance With Driving Conditions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
ES547950A 1984-10-18 1985-10-17 Perfeccionamientos en los aparatos para llevar a cabo secuencias reaccionales quimicas para la sintesis de polineucleotidos y otras moleculas de polimero. Expired ES8705352A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH499484 1984-10-18

Publications (2)

Publication Number Publication Date
ES547950A0 true ES547950A0 (es) 1987-05-01
ES8705352A1 ES8705352A1 (es) 1987-05-01

Family

ID=4286104

Family Applications (1)

Application Number Title Priority Date Filing Date
ES547950A Expired ES8705352A1 (es) 1984-10-18 1985-10-17 Perfeccionamientos en los aparatos para llevar a cabo secuencias reaccionales quimicas para la sintesis de polineucleotidos y otras moleculas de polimero.

Country Status (11)

Country Link
EP (1) EP0181491B1 (es)
JP (2) JPS61118141A (es)
AT (1) ATE44244T1 (es)
AU (1) AU558709B2 (es)
CA (1) CA1304916C (es)
DE (1) DE3571207D1 (es)
DK (1) DK466285A (es)
ES (1) ES8705352A1 (es)
FI (1) FI81505C (es)
IL (1) IL76662A0 (es)
NO (1) NO166582C (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8502612A1 (es) * 1983-06-15 1985-02-01 Schering Ag Procedimiento para la preparacion de 13a-alquilgonanos
EP0164206B1 (en) * 1984-05-02 1988-11-02 Brendan James Hamill An apparatus for the chemical synthesis of oligonucleotides
DE3631662A1 (de) * 1986-09-17 1988-03-24 Biotechnolog Forschung Gmbh Verfahren zur simultanen synthese mehrerer peptide an fester phase
DE3813671A1 (de) * 1988-04-22 1989-11-02 Europ Lab Molekularbiolog Vorrichtung zur durchfuehrung chemischer reaktionsfolgen
GB8823182D0 (en) * 1988-10-03 1988-11-09 Ici Plc Reactor elements reactors containing them & processes performed therein
DE4206488C2 (de) * 1992-03-02 1993-12-23 Deutsches Krebsforsch Vorrichtung zur Durchführung zeitgleich oder sequentiell ablaufender chemischer Reaktionen
CH684554A5 (de) * 1992-09-22 1994-10-14 Sotax Ag Probensammler.
JPH08505604A (ja) * 1992-11-06 1996-06-18 カイロン ミモトープス プロプライエトリー リミテッド モジュラーポリマーを合成するための支持体
US6469157B1 (en) 1993-12-16 2002-10-22 Proligo Llc Process for preparing polynucleotides on a solid support
FR2714061B1 (fr) * 1993-12-16 1996-03-08 Genset Sa Procédé de préparation de polynucléotides sur support solide et appareil permettant sa mise en Óoeuvre.
AU2990595A (en) * 1994-07-26 1996-02-22 Sydney Brenner Multidimensional conduit combinatorial library synthesis device
US6083682A (en) 1997-12-19 2000-07-04 Glaxo Group Limited System and method for solid-phase parallel synthesis of a combinatorial collection of compounds
DE59906395D1 (de) 1998-12-30 2003-08-28 Mwg Biotech Ag Vorrichtung zur durchführung von chemischen reaktionen
DE10042871A1 (de) * 2000-08-31 2002-05-16 Hte Ag The High Throughput Exp Dreidimensionale Materialbibliothek und Verfahren zur Herstellung einer dreidimensionalen Materialbibliothek
WO2006018043A2 (en) * 2004-08-18 2006-02-23 Agilent Technologies, Inc. Valve slider for a microfluidic coupling device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876881A (en) * 1973-10-24 1975-04-08 Hoffmann La Roche Protein monitor
US4483964A (en) * 1983-06-20 1984-11-20 Chiron Corporation Reactor system and method for polynucleotide synthesis
EP0164206B1 (en) * 1984-05-02 1988-11-02 Brendan James Hamill An apparatus for the chemical synthesis of oligonucleotides

Also Published As

Publication number Publication date
CA1304916C (en) 1992-07-14
NO854138L (no) 1986-04-21
FI81505B (fi) 1990-07-31
ATE44244T1 (de) 1989-07-15
DE3571207D1 (en) 1989-08-03
NO166582C (no) 1991-08-14
EP0181491A1 (de) 1986-05-21
AU4856185A (en) 1986-04-24
FI854050A0 (fi) 1985-10-17
DK466285A (da) 1986-04-19
JPS6344948A (ja) 1988-02-25
EP0181491B1 (de) 1989-06-28
AU558709B2 (en) 1987-02-05
IL76662A0 (en) 1986-02-28
FI854050L (fi) 1986-04-19
JPS61118141A (ja) 1986-06-05
NO166582B (no) 1991-05-06
DK466285D0 (da) 1985-10-11
ES8705352A1 (es) 1987-05-01
FI81505C (fi) 1990-11-12

Similar Documents

Publication Publication Date Title
ES547950A0 (es) Perfeccionamientos en los aparatos para llevar a cabo secuencias reaccionales quimicas para la sintesis de polineucleotidos y otras moleculas de polimero.
DK93888A (da) Fremgangsmaade til tilvejebringelse af kemiske reaktioner
CA2174140A1 (en) Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions
DK1073709T3 (da) Mikrofabrikeret apparat til cellebaserede assays
AU635143B2 (en) Analysis element and process for its manufacture
DK0693065T3 (da) Ikke-nucleosidiske cumarinderivater som reagenser til tværbinding af polynucleotider
WO1996017969A3 (en) Method and equipment for growing thin films
DK624986A (da) Fremgangsmaade til bestemmelse af mimotoper
FR2381731A1 (fr) Procede pour inhiber la polymerisation de composes vinylaromatiques facilement polymerisables
ES8301653A1 (es) Un procedimiento para la fabricacion de una fase solida estacionaria para columna de separacion molecular.
ES8801854A1 (es) Procedimiento para el estampado y tenido en continuo de materiales textiles con polimeros coloreados.
DK0472565T3 (da) Vandringslejereaktoranlæg
ATE243072T1 (de) Verfahren zur durchführung von stoffumwandlungen mit in flüssigkeiten suspendierten katalysatoren
DE3677539D1 (de) Polymere mit calixarensubstituenten.
ATE35255T1 (de) Optisch aktive (meth)-acrylamide, polymere daraus, verfahren zu ihrer herstellung und ihre verwendung zur racematspaltung.
ATE118176T1 (de) Endgruppen enthaltende affinitätsmembranen und verfahren zu deren herstellung und deren verwendung.
ATE32437T1 (de) Verfahren und reaktor zur durchfuehrung einer endothermen reaktion.
BR9003843A (pt) Processo para a preparacao de polimeros
DK0963246T3 (da) Indretning til en automatiseret kemisk syntese
EP0669388A3 (es)
DK0443923T3 (da) Nye aminophosphin-phosphiniter, fremgangsmåde til fremstilling af disse samt deres anvendelse i enantio-selektive reaktioner
SU874304A1 (ru) Устройство дл закреплени деталей
DK0475443T3 (da) Fremgangsmåde til kemisk syntese af oligonucleotider
SU1524913A1 (ru) Радиальный химический реактор
FI863289A (fi) Foerfarande foer dimerisering av eten selektivt till 1-buten.

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203