ES547826A0 - Un procedimiento para preparar nuevos derivados de 6-(4-fenilo sustituido -3(2h) piradazinona. - Google Patents
Un procedimiento para preparar nuevos derivados de 6-(4-fenilo sustituido -3(2h) piradazinona.Info
- Publication number
- ES547826A0 ES547826A0 ES547826A ES547826A ES547826A0 ES 547826 A0 ES547826 A0 ES 547826A0 ES 547826 A ES547826 A ES 547826A ES 547826 A ES547826 A ES 547826A ES 547826 A0 ES547826 A0 ES 547826A0
- Authority
- ES
- Spain
- Prior art keywords
- piradazinone
- procedure
- sup
- phenyl substituted
- new derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59213968A JPS6193169A (ja) | 1984-10-12 | 1984-10-12 | ピリダジノン誘導体及びその製法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES547826A0 true ES547826A0 (es) | 1986-12-16 |
| ES8702371A1 ES8702371A1 (es) | 1986-12-16 |
Family
ID=16648043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES547826A Expired ES8702371A1 (es) | 1984-10-12 | 1985-10-11 | Un procedimiento para preparar nuevos derivados de 6-(4-fenilo sustituido -3(2h) piradazinona. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4914093A (es) |
| EP (2) | EP0178189B1 (es) |
| JP (1) | JPS6193169A (es) |
| KR (1) | KR900002059B1 (es) |
| AT (2) | ATE94874T1 (es) |
| DE (2) | DE3581465D1 (es) |
| ES (1) | ES8702371A1 (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0613483B2 (ja) * | 1985-11-12 | 1994-02-23 | 三共株式会社 | フエニルピリダジノン誘導体 |
| JPS6314774A (ja) * | 1986-07-07 | 1988-01-21 | Mitsubishi Chem Ind Ltd | ピリダジノン誘導体又はその塩類 |
| US4888423A (en) * | 1986-10-06 | 1989-12-19 | Ciba-Geigy Corporation | 6-(4-Hydroxyphenyl)-4,5-dihydro-3(2h)-pyridazinones and stabilized compositions |
| US5019612A (en) * | 1986-10-06 | 1991-05-28 | Ciba-Geigy Corporation | 6-(4-hydroxyphenyl)-4,5-dihydro-3(2H)-pyridazinones and stabilized compositions |
| DE3728491A1 (de) * | 1987-08-26 | 1989-03-09 | Heumann Pharma Gmbh & Co | Dihydropyridazinon-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US5198448A (en) * | 1988-08-10 | 1993-03-30 | Otsuka Pharmaceutical Company, Limited | Cardiotonics |
| DE3902316A1 (de) * | 1989-01-26 | 1990-08-02 | Lentia Gmbh | Neue piperazinylalkyl-3(2h)-pyridazinone, verfahren zu ihrer herstellung und ihre verwendung als blutdrucksenkende mittel |
| US5175161A (en) * | 1989-04-06 | 1992-12-29 | Sankyo Company, Limited | Occular hypotensive agents |
| US5273976A (en) * | 1989-04-06 | 1993-12-28 | Sankyo Company, Limited | Ocular hypotensive agents |
| US5204463A (en) * | 1989-08-10 | 1993-04-20 | Glaxo Inc. | Substituted methoxyphenyl-4,5 dihydro-3(2H)-pridazinones having cardiotonic and beta blocking activities |
| IE902881A1 (en) * | 1989-08-10 | 1991-02-27 | Glaxo Inc | Pyridazinones having cardiotonic and beta blocking¹activities |
| US5096904A (en) * | 1989-09-01 | 1992-03-17 | Glaxo Inc. | Pyridazinones having cardiotonic and beta blocking activities |
| US5153209A (en) * | 1989-09-22 | 1992-10-06 | Glaxo Inc. | Pyridone nitriles useful in treating cardiovascular disease |
| US5051431A (en) * | 1989-09-22 | 1991-09-24 | Glaxo Inc. | Pyridone nitriles useful in treating cardiovascular disease |
| US5100892A (en) * | 1990-11-13 | 1992-03-31 | Glaxo Inc. | Dihydropyridine vasodilator agents |
| GB2251615B (en) * | 1991-01-03 | 1995-02-08 | Orion Yhtymae Oy | (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile |
| IL118631A (en) * | 1995-06-27 | 2002-05-23 | Tanabe Seiyaku Co | History of pyridazinone and processes for their preparation |
| MXPA05005661A (es) * | 2002-11-27 | 2005-11-23 | Artesian Therapeutics Inc | Compuestos con actividad antagonista o antagonista parcial mixta inhibidora de fosfodiesterasa y beta-adrenergica para el tratamiento de insuficiencia cardiaca. |
| AU2003300297A1 (en) * | 2002-12-23 | 2004-07-22 | Artesian Therapeutics, Inc. | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST Beta-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE |
| JP2008521805A (ja) * | 2004-11-30 | 2008-06-26 | アーテシアン セラピューティクス， インコーポレイテッド | β−アドレナリン作用性受容体およびホスホジエステラーゼに対する阻害活性を有する強心性化合物 |
| EP1830852A2 (en) * | 2004-11-30 | 2007-09-12 | Artesian Therapeutics, Inc. | Compounds with mixed pde-inhibitory and beta-adrenergic antagonist or partial agonist activity for treatment of heart failure |
| JP2006181097A (ja) * | 2004-12-27 | 2006-07-13 | Mammy's:Kk | 売り場構造及び商品陳列方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1383906A (en) * | 1971-02-22 | 1974-02-12 | Bdh Pharmaceuticals Ltd | Pyridazinones |
| GB1488330A (en) * | 1973-12-19 | 1977-10-12 | Smith Kline French Lab | Dihydropyridazinones |
| JPS588015A (ja) * | 1981-07-06 | 1983-01-18 | Mitsubishi Chem Ind Ltd | 強心剤 |
| US4816454A (en) * | 1984-09-21 | 1989-03-28 | Cassella Aktiengesellschaft | 4,5-dihydro-3(2H)-pyridazinones and their pharmacological use |
-
1984
- 1984-10-12 JP JP59213968A patent/JPS6193169A/ja active Granted
-
1985
- 1985-10-11 ES ES547826A patent/ES8702371A1/es not_active Expired
- 1985-10-12 KR KR1019850007521A patent/KR900002059B1/ko not_active IP Right Cessation
- 1985-10-14 DE DE8585307364T patent/DE3581465D1/de not_active Expired - Fee Related
- 1985-10-14 AT AT89105964T patent/ATE94874T1/de active
- 1985-10-14 EP EP85307364A patent/EP0178189B1/en not_active Expired - Lifetime
- 1985-10-14 DE DE89105964T patent/DE3587596T2/de not_active Expired - Fee Related
- 1985-10-14 AT AT85307364T patent/ATE60324T1/de not_active IP Right Cessation
- 1985-10-14 EP EP89105964A patent/EP0330242B1/en not_active Expired - Lifetime
-
1989
- 1989-03-16 US US07/325,112 patent/US4914093A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3587596T2 (de) | 1994-05-11 |
| EP0330242A1 (en) | 1989-08-30 |
| KR900002059B1 (ko) | 1990-03-31 |
| ES8702371A1 (es) | 1986-12-16 |
| DE3587596D1 (de) | 1993-10-28 |
| EP0178189A2 (en) | 1986-04-16 |
| KR860003232A (ko) | 1986-05-21 |
| DE3581465D1 (de) | 1991-02-28 |
| EP0178189B1 (en) | 1991-01-23 |
| ATE60324T1 (de) | 1991-02-15 |
| EP0330242B1 (en) | 1993-09-22 |
| ATE94874T1 (de) | 1993-10-15 |
| US4914093A (en) | 1990-04-03 |
| EP0178189A3 (en) | 1987-03-04 |
| JPS6193169A (ja) | 1986-05-12 |
| JPH0557983B2 (es) | 1993-08-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19971001 |