ES520024A0 - Procedimiento para la obtencion de nuevas piridazinonas. - Google Patents
Procedimiento para la obtencion de nuevas piridazinonas.Info
- Publication number
- ES520024A0 ES520024A0 ES520024A ES520024A ES520024A0 ES 520024 A0 ES520024 A0 ES 520024A0 ES 520024 A ES520024 A ES 520024A ES 520024 A ES520024 A ES 520024A ES 520024 A0 ES520024 A0 ES 520024A0
- Authority
- ES
- Spain
- Prior art keywords
- piridazinones
- procedure
- obtaining
- new
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 amino, acetylamino, methyl Chemical group 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229910052740 iodine Chemical group 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Treating Waste Gases (AREA)
- Curing Cements, Concrete, And Artificial Stone (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH144381 | 1981-03-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8403894A1 ES8403894A1 (es) | 1984-04-01 |
| ES520024A0 true ES520024A0 (es) | 1984-04-01 |
Family
ID=4210578
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES510055A Expired ES8308561A1 (es) | 1981-03-04 | 1982-03-02 | Procedimiento para la obtencion de nuevas piridazinonas. |
| ES520022A Expired ES8403892A1 (es) | 1981-03-04 | 1983-02-23 | Procedimiento para la obtencion de nuevas piridazinonas. |
| ES520023A Expired ES8403893A1 (es) | 1981-03-04 | 1983-02-23 | Procedimiento para la obtencion de nuevas piridazinonas. |
| ES520024A Granted ES520024A0 (es) | 1981-03-04 | 1983-02-23 | Procedimiento para la obtencion de nuevas piridazinonas. |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES510055A Expired ES8308561A1 (es) | 1981-03-04 | 1982-03-02 | Procedimiento para la obtencion de nuevas piridazinonas. |
| ES520022A Expired ES8403892A1 (es) | 1981-03-04 | 1983-02-23 | Procedimiento para la obtencion de nuevas piridazinonas. |
| ES520023A Expired ES8403893A1 (es) | 1981-03-04 | 1983-02-23 | Procedimiento para la obtencion de nuevas piridazinonas. |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US4613599A (es) |
| EP (1) | EP0059688B1 (es) |
| JP (1) | JPS57158762A (es) |
| AT (1) | ATE13294T1 (es) |
| AU (1) | AU558039B2 (es) |
| CA (1) | CA1180703A (es) |
| CY (1) | CY1396A (es) |
| DD (1) | DD209461A5 (es) |
| DE (1) | DE3263497D1 (es) |
| DK (1) | DK148772C (es) |
| ES (4) | ES8308561A1 (es) |
| FI (1) | FI72718C (es) |
| GB (1) | GB2094302B (es) |
| GR (1) | GR81397B (es) |
| HK (1) | HK87687A (es) |
| HU (1) | HU191083B (es) |
| IE (1) | IE52672B1 (es) |
| IL (1) | IL65161A (es) |
| MY (1) | MY8700736A (es) |
| NO (1) | NO158135C (es) |
| NZ (1) | NZ199892A (es) |
| PT (1) | PT74520B (es) |
| SG (1) | SG59587G (es) |
| ZA (1) | ZA821397B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4734415A (en) * | 1982-08-13 | 1988-03-29 | Warner-Lambert Company | Substituted 4,5-dihydro-6-(substituted)-phenyl-3(2H)-pyridazinones and 6-(substituted) phenyl-3(2H)-pyridazinones |
| GB8400863D0 (en) * | 1984-01-13 | 1984-02-15 | Smith Kline French Lab | Chemical compounds |
| GB8426804D0 (en) * | 1984-10-23 | 1984-11-28 | Ciba Geigy Ag | Pyridazinones preparations |
| JPS61158969A (ja) * | 1984-12-24 | 1986-07-18 | ワーナー‐ランバート・コンパニー | ４，５‐ジヒドロ‐４，４‐ジアルキル‐６‐（置換）フエニル‐３（２ｈ）‐ピリダジノン類 |
| IL79280A (en) * | 1985-07-05 | 1990-07-12 | Smith Kline French Lab | 4-(6-oxo-dihydro or tetrahydropyridazin-3-yl)benzene derivatives,their preparation and pharmaceutical compositions containing them |
| US4970210A (en) * | 1987-07-17 | 1990-11-13 | Abbott Laboratories | Triazinone lipoxygenase compounds |
| DE3735207A1 (de) * | 1987-10-17 | 1989-04-27 | Basf Ag | Mittel auf der basis von phenylpyridazinon-derivaten zur wachstumsfoerderung und fettreduktion bei tieren |
| EP2970145B1 (en) * | 2013-03-11 | 2020-05-06 | The Broad Institute, Inc. | Compounds and compositions for the treatment of cancer |
| US11897867B2 (en) | 2017-08-04 | 2024-02-13 | Bayer Aktiengesellschaft | 6-phenyl-4,5-dihydropyridazin-3(2H)-one derivatives as PDE3A and PDE3B inhibitors for treating cancer |
| JOP20200024A1 (ar) | 2017-08-04 | 2020-02-02 | Bayer Ag | مركبات ثنائي هيدروكساديازينون |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1488330A (en) * | 1923-02-01 | 1924-03-25 | Everitt James | Clothes-hanging bar formed of hinged-together members |
| IL37788A0 (en) * | 1970-10-09 | 1971-12-29 | American Cyanamid Co | New pyridazinone compounds,their preparation and pharmaceutical compositions containing them |
| GB1383906A (en) * | 1971-02-22 | 1974-02-12 | Bdh Pharmaceuticals Ltd | Pyridazinones |
| US3975388A (en) * | 1971-02-22 | 1976-08-17 | Bdh Pharmaceuticals Limited | Pyridazinones |
| GB1488330A (en) * | 1973-12-19 | 1977-10-12 | Smith Kline French Lab | Dihydropyridazinones |
| DE2854191A1 (de) * | 1978-12-15 | 1980-07-03 | Basf Ag | Dihydropyridazinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende therapeutische mittel |
-
1982
- 1982-02-26 FI FI820699A patent/FI72718C/fi not_active IP Right Cessation
- 1982-02-26 DE DE8282810090T patent/DE3263497D1/de not_active Expired
- 1982-02-26 AT AT82810090T patent/ATE13294T1/de active
- 1982-02-26 EP EP82810090A patent/EP0059688B1/de not_active Expired
- 1982-03-02 CY CY139682A patent/CY1396A/xx unknown
- 1982-03-02 CA CA000397433A patent/CA1180703A/en not_active Expired
- 1982-03-02 GB GB8205989A patent/GB2094302B/en not_active Expired
- 1982-03-02 ES ES510055A patent/ES8308561A1/es not_active Expired
- 1982-03-02 GR GR67459A patent/GR81397B/el unknown
- 1982-03-03 DK DK91782A patent/DK148772C/da not_active IP Right Cessation
- 1982-03-03 IL IL65161A patent/IL65161A/xx unknown
- 1982-03-03 NO NO820670A patent/NO158135C/no unknown
- 1982-03-03 ZA ZA821397A patent/ZA821397B/xx unknown
- 1982-03-03 DD DD82237856A patent/DD209461A5/de unknown
- 1982-03-03 NZ NZ199892A patent/NZ199892A/en unknown
- 1982-03-03 HU HU82652A patent/HU191083B/hu unknown
- 1982-03-03 IE IE478/82A patent/IE52672B1/en unknown
- 1982-03-03 PT PT74520A patent/PT74520B/pt unknown
- 1982-03-03 AU AU81065/82A patent/AU558039B2/en not_active Ceased
- 1982-03-04 JP JP57033169A patent/JPS57158762A/ja active Pending
-
1983
- 1983-02-23 ES ES520022A patent/ES8403892A1/es not_active Expired
- 1983-02-23 ES ES520023A patent/ES8403893A1/es not_active Expired
- 1983-02-23 ES ES520024A patent/ES520024A0/es active Granted
-
1985
- 1985-07-24 US US06/758,833 patent/US4613599A/en not_active Expired - Fee Related
-
1986
- 1986-05-05 US US06/859,684 patent/US4654340A/en not_active Expired - Fee Related
- 1986-11-28 US US06/935,901 patent/US4704391A/en not_active Expired - Fee Related
-
1987
- 1987-07-22 SG SG595/87A patent/SG59587G/en unknown
- 1987-11-26 HK HK876/87A patent/HK87687A/xx unknown
- 1987-12-30 MY MY736/87A patent/MY8700736A/xx unknown
Also Published As
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