ES512852A0 - "un procedimiento para preparar nuevos derivados de la n-dihidrotiazolil-3-quinolein-carboxamida". - Google Patents

"un procedimiento para preparar nuevos derivados de la n-dihidrotiazolil-3-quinolein-carboxamida".

Info

Publication number
ES512852A0
ES512852A0 ES512852A ES512852A ES512852A0 ES 512852 A0 ES512852 A0 ES 512852A0 ES 512852 A ES512852 A ES 512852A ES 512852 A ES512852 A ES 512852A ES 512852 A0 ES512852 A0 ES 512852A0
Authority
ES
Spain
Prior art keywords
dihydrotiazolyl
quinolein
carboxamide
procedure
new derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES512852A
Other languages
English (en)
Spanish (es)
Other versions
ES8304567A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8111607A external-priority patent/FR2507602A1/fr
Priority claimed from FR8204331A external-priority patent/FR2523130A1/fr
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES8304567A1 publication Critical patent/ES8304567A1/es
Publication of ES512852A0 publication Critical patent/ES512852A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES512852A 1981-06-12 1982-06-04 "un procedimiento para preparar nuevos derivados de la n-dihidrotiazolil-3-quinolein-carboxamida". Granted ES512852A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8111607A FR2507602A1 (fr) 1981-06-12 1981-06-12 Nouveau derive dihydrothiazole de la quinoleine, ses sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR8204331A FR2523130A1 (fr) 1982-03-15 1982-03-15 Nouveaux derives de la n-dihydrothiazolyl-3-quinoleine carboxamide, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant

Publications (2)

Publication Number Publication Date
ES8304567A1 ES8304567A1 (es) 1983-03-01
ES512852A0 true ES512852A0 (es) 1983-03-01

Family

ID=26222434

Family Applications (1)

Application Number Title Priority Date Filing Date
ES512852A Granted ES512852A0 (es) 1981-06-12 1982-06-04 "un procedimiento para preparar nuevos derivados de la n-dihidrotiazolil-3-quinolein-carboxamida".

Country Status (16)

Country Link
US (1) US4450166A (OSRAM)
EP (1) EP0067772B1 (OSRAM)
KR (1) KR880000808B1 (OSRAM)
AU (1) AU552029B2 (OSRAM)
CA (1) CA1216795A (OSRAM)
DE (1) DE3262536D1 (OSRAM)
DK (1) DK150070C (OSRAM)
ES (1) ES512852A0 (OSRAM)
FI (1) FI78087C (OSRAM)
GR (1) GR77201B (OSRAM)
HU (1) HU190796B (OSRAM)
IE (1) IE53520B1 (OSRAM)
IL (1) IL65943A (OSRAM)
MA (1) MA19488A1 (OSRAM)
NZ (1) NZ200931A (OSRAM)
PT (1) PT75023B (OSRAM)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2557570B1 (fr) * 1984-01-04 1986-04-18 Adir Nouveaux derives de la quinoleine, leur procede de preparation et les compositions pharmaceutiques les renfermant
FR2566405B1 (fr) * 1984-06-25 1986-09-26 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2 par une fonction aminee, leur preparation, leur application comme medicaments, les compositions les renfermant et les intermediaires nouveaux obtenus
US4602014A (en) * 1984-07-09 1986-07-22 Ciba-Geigy Corporation Ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives as benzodiazepine receptor modulators
US4560692A (en) * 1984-07-18 1985-12-24 Hoffmann-La Roche Inc. 4-Piperidino-2-phenylquinolines
US4786644A (en) * 1987-11-27 1988-11-22 Hoechst-Roussel Pharmaceuticals Inc. 1-aryl-3-quinolinecarboxamide
ATE296290T1 (de) 1998-02-26 2005-06-15 Neurogen Corp Substituierte cycloalkyl-4-oxonicotinische karboxamide; gaba gehirn-rezeptorligande
AU4818000A (en) * 1999-05-06 2000-11-21 Neurogen Corporation Substituted 4-oxo-quinoline-3-carboxamides: gaba brain receptor ligands
AU2005258320B2 (en) 2004-06-24 2010-09-16 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
CN101374849A (zh) * 2005-12-24 2009-02-25 沃泰克斯药物股份有限公司 作为abc转运蛋白调控剂的喹啉-4-酮衍生物
DK1993360T3 (en) * 2005-12-28 2017-05-22 Vertex Pharma SOLID FORMS OF N- [2,4-BIS (1,1-DIMETHYLETHYL) -5-HYDROXYPHENYL] -1,4-DIHYDRO-4-OXOQUINOLIN-3-CARBOXAMIDE
US12458635B2 (en) 2008-08-13 2025-11-04 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
CA2984994C (en) 2009-03-20 2020-03-31 Vertex Pharmaceuticals Incorporated Process for making modulators of cystic fibrosis transmembrane conductance regulator
US8802700B2 (en) 2010-12-10 2014-08-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
RU2692779C2 (ru) 2012-02-27 2019-06-27 Вертекс Фармасьютикалз Инкорпорейтед Фармацевтическая композиция и ее введения
KR20170063954A (ko) 2014-10-07 2017-06-08 버텍스 파마슈티칼스 인코포레이티드 낭성 섬유증 막횡단 전도도 조절자의 조정제의 공-결정

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1364605A (fr) * 1962-03-01 1964-06-26 Procédé de préparation d'amides des acides carboxyliques
FR2281761A1 (fr) * 1974-08-13 1976-03-12 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
FR2324304A2 (fr) * 1975-09-22 1977-04-15 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
FR2340735A1 (fr) * 1976-02-11 1977-09-09 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
FR2377400A2 (fr) * 1977-01-18 1978-08-11 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
FR2443467A1 (fr) * 1978-12-08 1980-07-04 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
FR2482596A1 (fr) * 1980-05-19 1981-11-20 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
DE3262536D1 (en) 1985-04-18
CA1216795A (fr) 1987-01-20
IL65943A (en) 1985-12-31
GR77201B (OSRAM) 1984-09-11
US4450166A (en) 1984-05-22
DK150070C (da) 1987-11-09
HU190796B (en) 1986-11-28
MA19488A1 (fr) 1982-12-31
IE53520B1 (en) 1988-12-07
FI822067A0 (fi) 1982-06-10
DK262782A (da) 1982-12-13
NZ200931A (en) 1984-12-14
FI78087B (fi) 1989-02-28
IE821394L (en) 1982-12-12
EP0067772A1 (fr) 1982-12-22
ES8304567A1 (es) 1983-03-01
AU8482782A (en) 1982-12-16
FI78087C (fi) 1989-06-12
PT75023B (fr) 1985-05-17
AU552029B2 (en) 1986-05-22
DK150070B (da) 1986-12-01
IL65943A0 (en) 1982-09-30
PT75023A (fr) 1982-07-01
EP0067772B1 (fr) 1985-03-13
KR880000808B1 (ko) 1988-05-11
KR840000541A (ko) 1984-02-25

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