ES505613A0 - Procedimiento para preparar un ester de alquilo de a-l-as- partil-l-fenilalamina - Google Patents

Procedimiento para preparar un ester de alquilo de a-l-as- partil-l-fenilalamina

Info

Publication number
ES505613A0
ES505613A0 ES505613A ES505613A ES505613A0 ES 505613 A0 ES505613 A0 ES 505613A0 ES 505613 A ES505613 A ES 505613A ES 505613 A ES505613 A ES 505613A ES 505613 A0 ES505613 A0 ES 505613A0
Authority
ES
Spain
Prior art keywords
alkyl ester
alpha
phenylalanine
preparing
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES505613A
Other languages
English (en)
Other versions
ES8302628A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chimicasa GmbH
Original Assignee
Chimicasa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chimicasa GmbH filed Critical Chimicasa GmbH
Publication of ES8302628A1 publication Critical patent/ES8302628A1/es
Publication of ES505613A0 publication Critical patent/ES505613A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801—Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES505613A 1980-09-19 1981-09-18 Procedimiento para preparar un ester de alquilo de a-l-as- partil-l-fenilalamina Granted ES505613A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/185,721 US4333872A (en) 1980-05-27 1980-09-19 Method of producing α-L-aspartyl-L-phenylalanine methylester

Publications (2)

Publication Number Publication Date
ES8302628A1 ES8302628A1 (es) 1982-12-01
ES505613A0 true ES505613A0 (es) 1982-12-01

Family

ID=22682204

Family Applications (1)

Application Number Title Priority Date Filing Date
ES505613A Granted ES505613A0 (es) 1980-09-19 1981-09-18 Procedimiento para preparar un ester de alquilo de a-l-as- partil-l-fenilalamina

Country Status (8)

Country Link
US (1) US4333872A (es)
EP (1) EP0048345B1 (es)
JP (1) JPS5782356A (es)
AT (1) ATE4703T1 (es)
DE (1) DE3160965D1 (es)
DK (1) DK415181A (es)
ES (1) ES505613A0 (es)
PT (1) PT73695B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3360104D1 (en) * 1982-07-20 1985-05-15 Eprova Ag Process for the preparation of lower alkyl esters of n-l-alpha-aspartyl-l-phenyl alanine, and intermediates for their manufacture
JPS5921656A (ja) * 1982-07-28 1984-02-03 Takeda Chem Ind Ltd ポリペプチド誘導体
EP0143881A3 (de) * 1983-09-07 1986-10-29 Gema S.A. Verfahren zur Herstellung eines alpha-L-Aspartyl-L-Phenylalanin-alkylesters
FR2558471B1 (fr) * 1984-01-19 1987-11-20 Isochem Sa Procede de preparation d'aspartyl peptides, et nouveaux intermediaires de synthese
ES8607216A1 (es) * 1984-01-19 1986-05-16 Isochem Sa Procedimiento de preparacion de &-aspartil peptidos
IT8419324A0 (it) * 1984-01-26 1984-01-26 Pierrel Spa Procedimento per la sintesi di derivati n-acilici dell'aspartame.
JPH0680074B2 (ja) * 1985-07-01 1994-10-12 味の素株式会社 Ｎ―ホルミル―Ｌ―α―アスパルチル―Ｌ―フェニルアラニンの製法
ES2042583T3 (es) * 1986-12-05 1993-12-16 Mitsui Toatsu Chemicals Preparacion de metil ester de alpha-l-aspartil-l-fenil-alanina o uno de sus hidrohaluros.
ES2042417B1 (es) * 1992-05-18 1994-06-01 Genesis Para La Investigacion Procedimiento de obtencion de alfa-aspartame.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3475403A (en) * 1967-01-20 1969-10-28 Searle & Co Aspartic acid containing dipeptide lower alkyl esters
US3786039A (en) * 1969-04-30 1974-01-15 Ajinomoto Kk Method of producing alpha-l-aspartyl-l-phenylalanine lower alkyl esters
US3830792A (en) * 1969-05-05 1974-08-20 Lilly Co Eli Method for synthesizing peptides using an excess of an unsymmetrical acid anhydride
BE791544A (fr) * 1971-11-19 1973-05-17 Stamicarbon Preparation d'esters alkyliques de dipeptide
US3901871A (en) * 1973-09-21 1975-08-26 American Cyanamid Co Process of preparing ' -l-aspartyl-l-phenylalanine methyl ester
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters

Also Published As

Publication number Publication date
ES8302628A1 (es) 1982-12-01
JPS5782356A (en) 1982-05-22
EP0048345A1 (de) 1982-03-31
US4333872A (en) 1982-06-08
EP0048345B1 (de) 1983-09-21
PT73695A (en) 1981-10-01
PT73695B (en) 1982-12-10
DE3160965D1 (en) 1983-10-27
ATE4703T1 (de) 1983-10-15
DK415181A (da) 1982-03-20

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