IL66689A - N-(n'-chloroethyl-n'-nitrosocarbamoyl)-oligopeptide esters and amides and method for their preparation - Google Patents
N-(n'-chloroethyl-n'-nitrosocarbamoyl)-oligopeptide esters and amides and method for their preparationInfo
- Publication number
- IL66689A IL66689A IL66689A IL6668982A IL66689A IL 66689 A IL66689 A IL 66689A IL 66689 A IL66689 A IL 66689A IL 6668982 A IL6668982 A IL 6668982A IL 66689 A IL66689 A IL 66689A
- Authority
- IL
- Israel
- Prior art keywords
- nitrosocarbamoyl
- chloroethyl
- amides
- preparation
- oligopeptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Compounds having the formula: <IMAGE> wherein: <IMAGE>R4 = -OCH3, -NH2, NH-R4, R4 being an oligopeptidic residue of which the terminal carboxyl group is blocked as a methyl ester or amide group. They are prepared by reacting the corresponding aminoacids or oligopeptides with an ester or an amide of a second aminoacid or of a second oligopeptide, in presence of an appropriate basic peptidic catalyst.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3134923A DE3134923C1 (en) | 1981-09-03 | 1981-09-03 | N- [N '- (2-chloroethyl) -N'-nitroso-carbamoyl] oligopeptide esters and amides and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL66689A true IL66689A (en) | 1986-02-28 |
Family
ID=6140795
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL66689A IL66689A (en) | 1981-09-03 | 1982-09-01 | N-(n'-chloroethyl-n'-nitrosocarbamoyl)-oligopeptide esters and amides and method for their preparation |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0074103B1 (en) |
| JP (1) | JPS58501769A (en) |
| AT (1) | ATE17735T1 (en) |
| AU (1) | AU8900982A (en) |
| BR (1) | BR8207845A (en) |
| DD (1) | DD209192A5 (en) |
| DE (2) | DE3134923C1 (en) |
| DK (1) | DK77583A (en) |
| FI (1) | FI830768L (en) |
| GR (1) | GR76534B (en) |
| HU (1) | HU190643B (en) |
| IL (1) | IL66689A (en) |
| MC (1) | MC1526A1 (en) |
| NO (1) | NO831475L (en) |
| WO (1) | WO1983000860A1 (en) |
| YU (1) | YU195982A (en) |
| ZA (1) | ZA826481B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2987263A (en) * | 1959-02-16 | 1961-06-06 | William R Senn | Apparatus for granulating phosphate rock fertilizer or the like |
| FR2540491A1 (en) * | 1983-02-08 | 1984-08-10 | Centre Nat Rech Scient | NOVEL NITROSOUREES, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF |
| JPS6288472A (en) * | 1985-10-14 | 1987-04-22 | Sharp Corp | Read and record control device for facsimile equipment |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5113722A (en) * | 1974-07-23 | 1976-02-03 | Suami T | Shinkina nitoroshinyosojudotaino seizoho |
-
1981
- 1981-09-03 DE DE3134923A patent/DE3134923C1/en not_active Expired
-
1982
- 1982-08-30 GR GR69161A patent/GR76534B/el unknown
- 1982-08-31 YU YU01959/82A patent/YU195982A/en unknown
- 1982-09-01 IL IL66689A patent/IL66689A/en unknown
- 1982-09-03 JP JP57502693A patent/JPS58501769A/en active Pending
- 1982-09-03 BR BR8207845A patent/BR8207845A/en unknown
- 1982-09-03 AU AU89009/82A patent/AU8900982A/en not_active Abandoned
- 1982-09-03 DD DD82243011A patent/DD209192A5/en unknown
- 1982-09-03 AT AT82108166T patent/ATE17735T1/en not_active IP Right Cessation
- 1982-09-03 WO PCT/EP1982/000191 patent/WO1983000860A1/en active Application Filing
- 1982-09-03 MC MC82EP8200191D patent/MC1526A1/en unknown
- 1982-09-03 HU HU823208A patent/HU190643B/en unknown
- 1982-09-03 DE DE8282108166T patent/DE3268831D1/en not_active Expired
- 1982-09-03 EP EP82108166A patent/EP0074103B1/en not_active Expired
- 1982-09-03 ZA ZA826481A patent/ZA826481B/en unknown
-
1983
- 1983-02-22 DK DK77583A patent/DK77583A/en not_active Application Discontinuation
- 1983-03-08 FI FI830768A patent/FI830768L/en not_active Application Discontinuation
- 1983-04-26 NO NO831475A patent/NO831475L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO831475L (en) | 1983-04-26 |
| FI830768A0 (en) | 1983-03-08 |
| ZA826481B (en) | 1983-07-27 |
| DE3134923C1 (en) | 1983-06-09 |
| AU8900982A (en) | 1983-03-28 |
| BR8207845A (en) | 1983-08-30 |
| FI830768L (en) | 1983-03-08 |
| WO1983000860A1 (en) | 1983-03-17 |
| EP0074103A1 (en) | 1983-03-16 |
| MC1526A1 (en) | 1984-04-13 |
| DE3268831D1 (en) | 1986-03-13 |
| JPS58501769A (en) | 1983-10-20 |
| HU190643B (en) | 1986-09-29 |
| DK77583A (en) | 1983-03-17 |
| ATE17735T1 (en) | 1986-02-15 |
| DD209192A5 (en) | 1984-04-25 |
| YU195982A (en) | 1985-08-31 |
| GR76534B (en) | 1984-08-10 |
| EP0074103B1 (en) | 1986-01-29 |
| DK77583D0 (en) | 1983-02-22 |
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