DK77583A - N- (N '- (2-CHLORETHYL) -N'-NITROSO-CARBAMOYL) -OOLOPEPTID ESTERS AND AMIDES AND PROCEDURES FOR THEIR PREPARATION - Google Patents

N- (N '- (2-CHLORETHYL) -N'-NITROSO-CARBAMOYL) -OOLOPEPTID ESTERS AND AMIDES AND PROCEDURES FOR THEIR PREPARATION Download PDF

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Publication number
DK77583A
DK77583A DK77583A DK77583A DK77583A DK 77583 A DK77583 A DK 77583A DK 77583 A DK77583 A DK 77583A DK 77583 A DK77583 A DK 77583A DK 77583 A DK77583 A DK 77583A
Authority
DK
Denmark
Prior art keywords
oolopeptid
chlorethyl
nitroso
carbamoyl
amides
Prior art date
Application number
DK77583A
Other languages
Danish (da)
Other versions
DK77583D0 (en
Inventor
Gerhard Eisenbrand
Wei-Ci Tang
Otto Zelesny
Original Assignee
Deutsches Krebsforsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforsch filed Critical Deutsches Krebsforsch
Publication of DK77583D0 publication Critical patent/DK77583D0/en
Publication of DK77583A publication Critical patent/DK77583A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Compounds having the formula: <IMAGE> wherein: <IMAGE>R4 = -OCH3, -NH2, NH-R4, R4 being an oligopeptidic residue of which the terminal carboxyl group is blocked as a methyl ester or amide group. They are prepared by reacting the corresponding aminoacids or oligopeptides with an ester or an amide of a second aminoacid or of a second oligopeptide, in presence of an appropriate basic peptidic catalyst.
DK77583A 1981-09-03 1983-02-22 N- (N '- (2-CHLORETHYL) -N'-NITROSO-CARBAMOYL) -OOLOPEPTID ESTERS AND AMIDES AND PROCEDURES FOR THEIR PREPARATION DK77583A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3134923A DE3134923C1 (en) 1981-09-03 1981-09-03 N- [N '- (2-chloroethyl) -N'-nitroso-carbamoyl] oligopeptide esters and amides and process for their preparation
PCT/EP1982/000191 WO1983000860A1 (en) 1981-09-03 1982-09-03 Oligopeptidic ester and amide n-adn'-(2-chlorethyl)-n'-nitroso-carbomoylbd and production method thereof

Publications (2)

Publication Number Publication Date
DK77583D0 DK77583D0 (en) 1983-02-22
DK77583A true DK77583A (en) 1983-03-17

Family

ID=6140795

Family Applications (1)

Application Number Title Priority Date Filing Date
DK77583A DK77583A (en) 1981-09-03 1983-02-22 N- (N '- (2-CHLORETHYL) -N'-NITROSO-CARBAMOYL) -OOLOPEPTID ESTERS AND AMIDES AND PROCEDURES FOR THEIR PREPARATION

Country Status (17)

Country Link
EP (1) EP0074103B1 (en)
JP (1) JPS58501769A (en)
AT (1) ATE17735T1 (en)
AU (1) AU8900982A (en)
BR (1) BR8207845A (en)
DD (1) DD209192A5 (en)
DE (2) DE3134923C1 (en)
DK (1) DK77583A (en)
FI (1) FI830768L (en)
GR (1) GR76534B (en)
HU (1) HU190643B (en)
IL (1) IL66689A (en)
MC (1) MC1526A1 (en)
NO (1) NO831475L (en)
WO (1) WO1983000860A1 (en)
YU (1) YU195982A (en)
ZA (1) ZA826481B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2987263A (en) * 1959-02-16 1961-06-06 William R Senn Apparatus for granulating phosphate rock fertilizer or the like

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540491A1 (en) * 1983-02-08 1984-08-10 Centre Nat Rech Scient NOVEL NITROSOUREES, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF
JPS6288472A (en) * 1985-10-14 1987-04-22 Sharp Corp Read and record control device for facsimile equipment

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5113722A (en) * 1974-07-23 1976-02-03 Suami T Shinkina nitoroshinyosojudotaino seizoho

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2987263A (en) * 1959-02-16 1961-06-06 William R Senn Apparatus for granulating phosphate rock fertilizer or the like

Also Published As

Publication number Publication date
NO831475L (en) 1983-04-26
ZA826481B (en) 1983-07-27
YU195982A (en) 1985-08-31
DE3134923C1 (en) 1983-06-09
FI830768A0 (en) 1983-03-08
AU8900982A (en) 1983-03-28
DD209192A5 (en) 1984-04-25
MC1526A1 (en) 1984-04-13
EP0074103B1 (en) 1986-01-29
EP0074103A1 (en) 1983-03-16
DE3268831D1 (en) 1986-03-13
BR8207845A (en) 1983-08-30
FI830768L (en) 1983-03-08
GR76534B (en) 1984-08-10
HU190643B (en) 1986-09-29
WO1983000860A1 (en) 1983-03-17
IL66689A (en) 1986-02-28
DK77583D0 (en) 1983-02-22
JPS58501769A (en) 1983-10-20
ATE17735T1 (en) 1986-02-15

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment