ES486040A1 - Procedimiento para la obtencion de derivados de polieter - Google Patents

Procedimiento para la obtencion de derivados de polieter

Info

Publication number
ES486040A1
ES486040A1 ES486040A ES486040A ES486040A1 ES 486040 A1 ES486040 A1 ES 486040A1 ES 486040 A ES486040 A ES 486040A ES 486040 A ES486040 A ES 486040A ES 486040 A1 ES486040 A1 ES 486040A1
Authority
ES
Spain
Prior art keywords
pharmaceuticals
preparation
polyether derivatives
polyethers
oxide proportion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES486040A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES486040A1 publication Critical patent/ES486040A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/321—Polymers modified by chemical after-treatment with inorganic compounds
    • C08G65/326—Polymers modified by chemical after-treatment with inorganic compounds containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/321—Polymers modified by chemical after-treatment with inorganic compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C08G65/3324—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof cyclic
    • C08G65/3326—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof cyclic aromatic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/337—Polymers modified by chemical after-treatment with organic compounds containing other elements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyethers (AREA)
  • Medicinal Preparation (AREA)

Abstract

Procedimiento para la obtención de derivados de poliéter de fórmula general (I): **(Fórmula)** donde X en cada caso, significa oxígeno, azufre, un grupo NH o un grupo N-alquilo, R{sub,1} significa alquilo, alquenilo, cicloalquilo, cicloalquenilo, arilo, o aralquilo, donde estos grupos pueden estar en caso dado sustituidos por nitro, ciano, azido, halógeno, trifluormetilo, trifluormetoxi, fenilo, hidroxi, amino, alquilo, alcoxi, alcoxicarbonilo, aciloxi, acilamino, hidroxi, carboxi o SO{sub,2}-alquilo y a, b y c representan números enteros que se han seleccionado de manera que resulte un peso molecular medio de 3000 - 5000 y que en la proporción de óxido propilénico (b) ascienda a un 60 hasta 80% y la proporción en óxido etilénico (a y c) a un 20 - 40%.
ES486040A 1978-11-18 1979-11-16 Procedimiento para la obtencion de derivados de polieter Expired ES486040A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782850058 DE2850058A1 (de) 1978-11-18 1978-11-18 Polyaether-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ES486040A1 true ES486040A1 (es) 1980-05-16

Family

ID=6054997

Family Applications (1)

Application Number Title Priority Date Filing Date
ES486040A Expired ES486040A1 (es) 1978-11-18 1979-11-16 Procedimiento para la obtencion de derivados de polieter

Country Status (7)

Country Link
US (1) US4330677A (es)
EP (1) EP0011237A1 (es)
JP (1) JPS5571720A (es)
CA (1) CA1149407A (es)
DE (1) DE2850058A1 (es)
DK (1) DK488379A (es)
ES (1) ES486040A1 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2467838A1 (fr) * 1979-10-16 1981-04-30 Oreal Nouveaux composes non-ioniques polyoxyethylenes a deux chaines lipophiles, leur procede de preparation et compositions les contenant
DE3136025A1 (de) * 1981-09-11 1983-03-24 Hoechst Ag, 6000 Frankfurt "polymere ethylenoxid-propylenoxid- oder ethylenoxid-butylenoxid-ethercarbonsaeuren, verfahren zu deren herstellung und deren verwendung"
LU84979A1 (fr) * 1983-08-30 1985-04-24 Oreal Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
US5037969A (en) * 1986-07-03 1991-08-06 Takeda Chemical Industries, Ltd. Glycosyl derivatives and use thereof
US5674911A (en) * 1987-02-20 1997-10-07 Cytrx Corporation Antiinfective polyoxypropylene/polyoxyethylene copolymers and methods of use
US5811088A (en) * 1987-02-20 1998-09-22 Emory University Antiinfective compounds and methods of use
US5093198A (en) * 1987-06-19 1992-03-03 Temple University Adjuvant-enhanced sustained release composition and method for making
JPH01126327A (ja) * 1987-06-30 1989-05-18 Union Carbide Corp Ｎ−（ポリオキシアルキル）−ｎ−（アルキル）アミン
DE3825637A1 (de) * 1988-07-28 1990-03-08 Rwe Dea Ag Sekundaere polyetheramine, ihre herstellung und verwendung zur herstellung von polyharnstoffen
US5283339A (en) * 1988-11-23 1994-02-01 California Institute Of Technology Immobilized metal aqueous two-phase extraction and precipitation
DE3901613A1 (de) * 1989-01-20 1990-08-16 Basf Ag Glycerinaminocarboxylate, ihre herstellung und verwendung
US5260484A (en) * 1989-12-22 1993-11-09 Basf Aktiengesellschaft Polytetrahydrofuran derivatives having terminal aromatic groups
US6933286B2 (en) 1991-03-19 2005-08-23 R. Martin Emanuele Therapeutic delivery compositions and methods of use thereof
ES2140408T3 (es) 1991-03-19 2000-03-01 Cytrx Corp Copolimeros de polioxipropileno/polioxietileno con actividad biologica mejorada.
US7202225B1 (en) 1993-10-15 2007-04-10 Emanuele R Martin Therapeutic delivery compositions and methods of use thereof
AU4899093A (en) * 1992-10-13 1994-04-28 Pacesetter Ab Compound and method of applying anti-fouling coatings on medical devices
US5516703A (en) * 1993-08-20 1996-05-14 The University Of Utah Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands
US6284503B1 (en) 1993-08-20 2001-09-04 University Of Utah Research Foundation Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces
GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
US5441544A (en) * 1993-12-23 1995-08-15 Chevron Chemical Company Fuel compositions containing substituted poly(oxyalkylene) aromatic ethers
EP0907666A1 (en) 1996-06-27 1999-04-14 G.D. Searle & Co. Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications
BR0211002A (pt) * 2001-06-15 2004-08-10 Huntsman Spec Chem Corp Extensores de cadeia de amina sinergistica em elastomeros pulverizados de poliureia
US7205337B2 (en) * 2001-12-21 2007-04-17 Isotis Orthobiologics, Inc. End-capped polymers and compositions containing such compounds
EP1456278B1 (en) * 2001-12-21 2006-03-08 IsoTis Orthobiologics, Inc. Compositions containing end-capped polyalkylene glycols
US20040015016A1 (en) * 2002-07-22 2004-01-22 Huntsman Petrochemical Corporation Preparation of secondary amines
US7157549B2 (en) * 2003-05-30 2007-01-02 The University Of Akron Polymerization of oxiranes with a lithium-containing initiator
WO2006078163A2 (en) * 2005-01-18 2006-07-27 Dolphys Technologies B.V. High molecular weight non-ionic surfactants comprising nitrogen or phosphorus containing groups
TR201910570T4 (tr) * 2011-01-13 2019-08-21 Basf Se Polialkilen oksitlerin gerektiği takdirde okside edilmiş tioeterlerinin yıkama ve temizleme maddeleri içerisinde kullanımı.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2010154A (en) * 1933-06-27 1935-08-06 Herbert S Kreighbaum Ether acid ester of polyhydric alcohols
US2662859A (en) * 1949-06-15 1953-12-15 Visco Products Co Compositions and process for emulsion breaking
US2653972A (en) * 1950-06-09 1953-09-29 Wyandotte Chemicals Corp Process of producing lower alkyl-, carboxymethyl-, diethers of polyoxyalkylene glycols
ES334486A1 (es) * 1965-12-23 1967-11-01 Smith Kline & French Laboratories Un procedimiento para la preparacion de una composicion farmaceutica que comprende la mezcla de un polimero de polioxipropileno-polioxietileno.
FR1536689A (fr) * 1966-09-26 1968-08-16 Basf Ag Procédé de destruction d'émulsions eau-dans-huile
US3983171A (en) * 1967-08-07 1976-09-28 L'oreal Anionic surface active compositions
US3959460A (en) * 1967-08-07 1976-05-25 L'oreal Cosmetic compositions containing anionic surface active agent containing mono- or polyhydroxylated mono- or poly ether chains and a terminal acid group
JPS5213597B2 (es) * 1973-12-29 1977-04-15
DE2732929A1 (de) * 1977-07-21 1979-02-01 Bayer Ag Polyaether, verfahren zu ihrer herstellung sowie ihre verwendung als lipidabsorptionshemmer

Also Published As

Publication number Publication date
CA1149407A (en) 1983-07-05
DK488379A (da) 1980-05-19
JPS5571720A (en) 1980-05-30
DE2850058A1 (de) 1980-05-29
US4330677A (en) 1982-05-18
EP0011237A1 (de) 1980-05-28

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