ES486040A1 - Procedimiento para la obtencion de derivados de polieter - Google Patents
Procedimiento para la obtencion de derivados de polieterInfo
- Publication number
- ES486040A1 ES486040A1 ES486040A ES486040A ES486040A1 ES 486040 A1 ES486040 A1 ES 486040A1 ES 486040 A ES486040 A ES 486040A ES 486040 A ES486040 A ES 486040A ES 486040 A1 ES486040 A1 ES 486040A1
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceuticals
- preparation
- polyether derivatives
- polyethers
- oxide proportion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/321—Polymers modified by chemical after-treatment with inorganic compounds
- C08G65/326—Polymers modified by chemical after-treatment with inorganic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/77—Polymers containing oxygen of oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/321—Polymers modified by chemical after-treatment with inorganic compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
- C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
- C08G65/3324—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof cyclic
- C08G65/3326—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof cyclic aromatic
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/337—Polymers modified by chemical after-treatment with organic compounds containing other elements
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polyethers (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
Procedimiento para la obtención de derivados de poliéter de fórmula general (I): **(Fórmula)** donde X en cada caso, significa oxígeno, azufre, un grupo NH o un grupo N-alquilo, R{sub,1} significa alquilo, alquenilo, cicloalquilo, cicloalquenilo, arilo, o aralquilo, donde estos grupos pueden estar en caso dado sustituidos por nitro, ciano, azido, halógeno, trifluormetilo, trifluormetoxi, fenilo, hidroxi, amino, alquilo, alcoxi, alcoxicarbonilo, aciloxi, acilamino, hidroxi, carboxi o SO{sub,2}-alquilo y a, b y c representan números enteros que se han seleccionado de manera que resulte un peso molecular medio de 3000 - 5000 y que en la proporción de óxido propilénico (b) ascienda a un 60 hasta 80% y la proporción en óxido etilénico (a y c) a un 20 - 40%.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19782850058 DE2850058A1 (de) | 1978-11-18 | 1978-11-18 | Polyaether-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ES486040A1 true ES486040A1 (es) | 1980-05-16 |
Family
ID=6054997
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES486040A Expired ES486040A1 (es) | 1978-11-18 | 1979-11-16 | Procedimiento para la obtencion de derivados de polieter |
Country Status (7)
Country | Link |
---|---|
US (1) | US4330677A (es) |
EP (1) | EP0011237A1 (es) |
JP (1) | JPS5571720A (es) |
CA (1) | CA1149407A (es) |
DE (1) | DE2850058A1 (es) |
DK (1) | DK488379A (es) |
ES (1) | ES486040A1 (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2467838A1 (fr) * | 1979-10-16 | 1981-04-30 | Oreal | Nouveaux composes non-ioniques polyoxyethylenes a deux chaines lipophiles, leur procede de preparation et compositions les contenant |
DE3136025A1 (de) * | 1981-09-11 | 1983-03-24 | Hoechst Ag, 6000 Frankfurt | "polymere ethylenoxid-propylenoxid- oder ethylenoxid-butylenoxid-ethercarbonsaeuren, verfahren zu deren herstellung und deren verwendung" |
LU84979A1 (fr) * | 1983-08-30 | 1985-04-24 | Oreal | Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux |
US5037969A (en) * | 1986-07-03 | 1991-08-06 | Takeda Chemical Industries, Ltd. | Glycosyl derivatives and use thereof |
US5811088A (en) * | 1987-02-20 | 1998-09-22 | Emory University | Antiinfective compounds and methods of use |
US5674911A (en) * | 1987-02-20 | 1997-10-07 | Cytrx Corporation | Antiinfective polyoxypropylene/polyoxyethylene copolymers and methods of use |
US5093198A (en) * | 1987-06-19 | 1992-03-03 | Temple University | Adjuvant-enhanced sustained release composition and method for making |
JPH01126327A (ja) * | 1987-06-30 | 1989-05-18 | Union Carbide Corp | N−(ポリオキシアルキル)−n−(アルキル)アミン |
DE3825637A1 (de) * | 1988-07-28 | 1990-03-08 | Rwe Dea Ag | Sekundaere polyetheramine, ihre herstellung und verwendung zur herstellung von polyharnstoffen |
US5283339A (en) * | 1988-11-23 | 1994-02-01 | California Institute Of Technology | Immobilized metal aqueous two-phase extraction and precipitation |
DE3901613A1 (de) * | 1989-01-20 | 1990-08-16 | Basf Ag | Glycerinaminocarboxylate, ihre herstellung und verwendung |
US5260484A (en) * | 1989-12-22 | 1993-11-09 | Basf Aktiengesellschaft | Polytetrahydrofuran derivatives having terminal aromatic groups |
US7202225B1 (en) | 1993-10-15 | 2007-04-10 | Emanuele R Martin | Therapeutic delivery compositions and methods of use thereof |
US6933286B2 (en) | 1991-03-19 | 2005-08-23 | R. Martin Emanuele | Therapeutic delivery compositions and methods of use thereof |
HUT67762A (en) * | 1991-03-19 | 1995-04-28 | Cytrx Corp | Polyoxypropylene/polyoxiethylene copolymers with improved biological activity and process for producing thereof |
AU4899093A (en) * | 1992-10-13 | 1994-04-28 | Pacesetter Ab | Compound and method of applying anti-fouling coatings on medical devices |
US5516703A (en) * | 1993-08-20 | 1996-05-14 | The University Of Utah | Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands |
US6284503B1 (en) * | 1993-08-20 | 2001-09-04 | University Of Utah Research Foundation | Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces |
GB2281697A (en) * | 1993-09-14 | 1995-03-15 | Euro Celtique Sa | Laxative compositions in capsules |
US5441544A (en) * | 1993-12-23 | 1995-08-15 | Chevron Chemical Company | Fuel compositions containing substituted poly(oxyalkylene) aromatic ethers |
WO1997049387A1 (en) | 1996-06-27 | 1997-12-31 | G.D. Searle And Co. | Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications |
BR0211002A (pt) * | 2001-06-15 | 2004-08-10 | Huntsman Spec Chem Corp | Extensores de cadeia de amina sinergistica em elastomeros pulverizados de poliureia |
US7205337B2 (en) * | 2001-12-21 | 2007-04-17 | Isotis Orthobiologics, Inc. | End-capped polymers and compositions containing such compounds |
EP1456278B1 (en) * | 2001-12-21 | 2006-03-08 | IsoTis Orthobiologics, Inc. | Compositions containing end-capped polyalkylene glycols |
US20040015016A1 (en) * | 2002-07-22 | 2004-01-22 | Huntsman Petrochemical Corporation | Preparation of secondary amines |
US7157549B2 (en) * | 2003-05-30 | 2007-01-02 | The University Of Akron | Polymerization of oxiranes with a lithium-containing initiator |
WO2006078163A2 (en) * | 2005-01-18 | 2006-07-27 | Dolphys Technologies B.V. | High molecular weight non-ionic surfactants comprising nitrogen or phosphorus containing groups |
CA2822897A1 (en) * | 2011-01-13 | 2012-07-19 | Basf Se | Use of optionally oxidized thioethers of polyalkylene oxides in detergents and cleaning agents |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2010154A (en) * | 1933-06-27 | 1935-08-06 | Herbert S Kreighbaum | Ether acid ester of polyhydric alcohols |
US2662859A (en) * | 1949-06-15 | 1953-12-15 | Visco Products Co | Compositions and process for emulsion breaking |
US2653972A (en) * | 1950-06-09 | 1953-09-29 | Wyandotte Chemicals Corp | Process of producing lower alkyl-, carboxymethyl-, diethers of polyoxyalkylene glycols |
ES334486A1 (es) * | 1965-12-23 | 1967-11-01 | Smith Kline & French Laboratories | Un procedimiento para la preparacion de una composicion farmaceutica que comprende la mezcla de un polimero de polioxipropileno-polioxietileno. |
FR1536689A (fr) * | 1966-09-26 | 1968-08-16 | Basf Ag | Procédé de destruction d'émulsions eau-dans-huile |
US3959460A (en) * | 1967-08-07 | 1976-05-25 | L'oreal | Cosmetic compositions containing anionic surface active agent containing mono- or polyhydroxylated mono- or poly ether chains and a terminal acid group |
US3983171A (en) * | 1967-08-07 | 1976-09-28 | L'oreal | Anionic surface active compositions |
JPS5213597B2 (es) * | 1973-12-29 | 1977-04-15 | ||
DE2732929A1 (de) * | 1977-07-21 | 1979-02-01 | Bayer Ag | Polyaether, verfahren zu ihrer herstellung sowie ihre verwendung als lipidabsorptionshemmer |
-
1978
- 1978-11-18 DE DE19782850058 patent/DE2850058A1/de not_active Withdrawn
-
1979
- 1979-10-31 US US06/089,839 patent/US4330677A/en not_active Expired - Lifetime
- 1979-11-08 EP EP79104382A patent/EP0011237A1/de not_active Withdrawn
- 1979-11-16 CA CA000339974A patent/CA1149407A/en not_active Expired
- 1979-11-16 DK DK488379A patent/DK488379A/da unknown
- 1979-11-16 JP JP14789079A patent/JPS5571720A/ja active Pending
- 1979-11-16 ES ES486040A patent/ES486040A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS5571720A (en) | 1980-05-30 |
EP0011237A1 (de) | 1980-05-28 |
CA1149407A (en) | 1983-07-05 |
DE2850058A1 (de) | 1980-05-29 |
DK488379A (da) | 1980-05-19 |
US4330677A (en) | 1982-05-18 |
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