ES485733A1 - Procedimiento para la obtencion de derivados de esteres de 1,1,2-trifenilalqueno - Google Patents

Procedimiento para la obtencion de derivados de esteres de 1,1,2-trifenilalqueno

Info

Publication number
ES485733A1
ES485733A1 ES485733A ES485733A ES485733A1 ES 485733 A1 ES485733 A1 ES 485733A1 ES 485733 A ES485733 A ES 485733A ES 485733 A ES485733 A ES 485733A ES 485733 A1 ES485733 A1 ES 485733A1
Authority
ES
Spain
Prior art keywords
derivatives
acyloxyphenyl
manufacture
processes
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES485733A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of ES485733A1 publication Critical patent/ES485733A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Gas-Filled Discharge Tubes (AREA)
  • Magnetic Ceramics (AREA)

Abstract

Procedimiento para la obtención de derivados de ésteres de 1,1,2-trifenilalqueno, de fórmula: **(Fórmula)** en donde bien R1 es un átomo de hidrógeno o un radical alquilo inferior y R2 es un radical alquilo inferior, o R1 y R2 están unidos conjuntamente con el átomo de nitrógeno adyacente para formar un radical heterocíclico; n es 2, 3, 4, 5 ó 6; R3 es un átomo de halógeno o un radical alquilo inferior; R4 es un átomo de hidrógeno o halógeno, o un radical hidroxi, un radical alquilo inferior o un radical alcoxi inferior, o es el radical buta-1,3-dienilo de manera que junto con el anillo benceno forma un radical naftilo, o R4 tiene la fórmula - OCOR5; y R5 es un radical alquilo de 1 a 10 átomos de carbono o un radical alcoxialquilo de 2 a 10 átomos de carbono.
ES485733A 1978-11-07 1979-11-06 Procedimiento para la obtencion de derivados de esteres de 1,1,2-trifenilalqueno Expired ES485733A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7843430 1978-11-07

Publications (1)

Publication Number Publication Date
ES485733A1 true ES485733A1 (es) 1980-07-01

Family

ID=10500848

Family Applications (1)

Application Number Title Priority Date Filing Date
ES485733A Expired ES485733A1 (es) 1978-11-07 1979-11-06 Procedimiento para la obtencion de derivados de esteres de 1,1,2-trifenilalqueno

Country Status (18)

Country Link
EP (1) EP0011372B1 (es)
JP (1) JPS5566547A (es)
AT (1) ATE2423T1 (es)
AU (1) AU533581B2 (es)
CA (1) CA1120945A (es)
DD (1) DD147234A5 (es)
DE (1) DE2964736D1 (es)
DK (1) DK471979A (es)
ES (1) ES485733A1 (es)
FI (1) FI793459A (es)
GR (1) GR71202B (es)
HU (1) HU179722B (es)
IL (1) IL58587A (es)
NO (1) NO793578L (es)
NZ (1) NZ191916A (es)
PT (1) PT70411A (es)
ZA (1) ZA795658B (es)
ZW (1) ZW21179A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3239610A1 (de) * 1982-10-26 1984-04-26 Klinge Pharma GmbH, 8000 München Neue 1,1,2-triphenyl-but-l-en-derivate, sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
EP0221368A3 (de) * 1985-10-31 1988-05-04 ASTA Pharma Aktiengesellschaft Substituierte 1,1,2-Triphenylbut-1-ene
US5204337A (en) * 1988-10-31 1993-04-20 Endorecherche Inc. Estrogen nucleus derivatives for use in inhibition of sex steroid activity
US5364847A (en) * 1989-03-10 1994-11-15 Endorecherche Inhibitors of sex steroid biosynthesis and methods for their production and use
ZA924811B (en) * 1991-06-28 1993-12-29 Endorecherche Inc Controlled release systems and low dose androgens
GB9824207D0 (en) * 1998-11-04 1998-12-30 Zeneca Ltd Neurological disorders
DK1175433T3 (da) 1999-05-04 2005-09-19 Strakan Int Ltd Androgenglycosider og androgen aktivitet deraf
US7531578B2 (en) * 2003-09-18 2009-05-12 City Of Hope Compounds and methods for treating breast cancer and other diseases
JP4940429B2 (ja) * 2006-09-19 2012-05-30 国立大学法人 岡山大学 トリアリールエチルエテン誘導体の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2914564A (en) * 1957-08-06 1959-11-24 Wm S Merrell Co Amine derivatives of 1, 1, 2-triphenylethane
GB916171A (en) * 1959-02-25 1963-01-23 Ferrosan Ab Improvements in or relating to diphenyl ethylene compounds having oestrogenic activity and processes for their preparation
GB945864A (en) * 1961-08-18 1964-01-08 Richardson Merrell Inc Substituted triphenylethane
GB1029221A (en) * 1963-09-02 1966-05-11 Ici Ltd Triarylalkane derivatives
HU171269B (hu) * 1976-02-05 1977-12-28 Gyogyszerkutato Intezet Sposob poluchenija novykh proizvodnykh trifenil-alkenov
GB1560274A (en) * 1977-02-28 1980-02-06 Ici Ltd Phenylbut 1-ene derivatives having antiostrogenicactivity

Also Published As

Publication number Publication date
IL58587A0 (en) 1980-01-31
JPS5566547A (en) 1980-05-20
NZ191916A (en) 1984-09-28
ATE2423T1 (de) 1983-03-15
FI793459A (fi) 1980-05-08
EP0011372A1 (en) 1980-05-28
CA1120945A (en) 1982-03-30
EP0011372B1 (en) 1983-02-09
JPS638934B2 (es) 1988-02-25
DK471979A (da) 1980-05-08
ZA795658B (en) 1981-03-25
DE2964736D1 (en) 1983-03-17
ZW21179A1 (en) 1981-05-27
IL58587A (en) 1983-03-31
NO793578L (no) 1980-05-08
HU179722B (en) 1982-11-29
DD147234A5 (de) 1981-03-25
GR71202B (es) 1983-04-11
AU5223279A (en) 1980-05-15
PT70411A (en) 1979-12-01
AU533581B2 (en) 1983-12-01

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