ES480163A1 - Procedimiento de preparacion de nuevos derivados sustituidos de acidos 4h-1-benzodioxin-2- carboxilicos. - Google Patents

Procedimiento de preparacion de nuevos derivados sustituidos de acidos 4h-1-benzodioxin-2- carboxilicos.

Info

Publication number
ES480163A1
ES480163A1 ES480163A ES480163A ES480163A1 ES 480163 A1 ES480163 A1 ES 480163A1 ES 480163 A ES480163 A ES 480163A ES 480163 A ES480163 A ES 480163A ES 480163 A1 ES480163 A1 ES 480163A1
Authority
ES
Spain
Prior art keywords
hydrogen
alkyl
carbon atoms
group
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES480163A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7813095A external-priority patent/FR2424915A1/fr
Priority claimed from FR7813096A external-priority patent/FR2424916A1/fr
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES480163A1 publication Critical patent/ES480163A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/081,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/17Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24Halogenated derivatives
    • C07C39/26Halogenated derivatives monocyclic monohydroxylic containing halogen bound to ring carbon atoms
    • C07C39/27Halogenated derivatives monocyclic monohydroxylic containing halogen bound to ring carbon atoms all halogen atoms being bound to ring carbon atoms
    • C07C39/28Halogenated derivatives monocyclic monohydroxylic containing halogen bound to ring carbon atoms all halogen atoms being bound to ring carbon atoms the halogen being one chlorine atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24Halogenated derivatives
    • C07C39/367Halogenated derivatives polycyclic non-condensed, containing only six-membered aromatic rings as cyclic parts, e.g. halogenated poly-hydroxyphenylalkanes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24Halogenated derivatives
    • C07C39/373Halogenated derivatives with all hydroxy groups on non-condensed rings and with unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24Halogenated derivatives
    • C07C39/42Halogenated derivatives containing six-membered aromatic rings and other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01Preparation of ethers
    • C07C41/18Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/30Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedimiento de preparación de nuevos derivados sustituidos de ácidos [4H]-1-benzodioxin-2-carboxílicos de la fórmula general I: *** en la cual o bien R1 representa un átomo de hidrógeno, un radical alcohilo que contiene de 1 a 5 átomos de carbono, un radical dialcohilaminoalcohilo, cuyos radicales alcohilos contienen de 1 a 5 átomos de carbono.
ES480163A 1978-05-03 1979-05-02 Procedimiento de preparacion de nuevos derivados sustituidos de acidos 4h-1-benzodioxin-2- carboxilicos. Expired ES480163A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7813095A FR2424915A1 (fr) 1978-05-03 1978-05-03 Nouveaux derives d'acides /4h/ 1-3 benzodioxin-2-carboxyliques, un procede pour leur preparation et leur application comme medicaments
FR7813096A FR2424916A1 (fr) 1978-05-03 1978-05-03 Nouveaux derives substitues d'acides, 1,3-benzodioxin-2-carboxyliques, procede pour leur preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
ES480163A1 true ES480163A1 (es) 1979-10-16

Family

ID=26220579

Family Applications (1)

Application Number Title Priority Date Filing Date
ES480163A Expired ES480163A1 (es) 1978-05-03 1979-05-02 Procedimiento de preparacion de nuevos derivados sustituidos de acidos 4h-1-benzodioxin-2- carboxilicos.

Country Status (10)

Country Link
US (1) US4281012A (es)
JP (1) JPS54144382A (es)
CH (1) CH640233A5 (es)
DE (1) DE2917902A1 (es)
DK (1) DK180179A (es)
ES (1) ES480163A1 (es)
GB (1) GB2022579B (es)
IT (1) IT1116836B (es)
NL (1) NL7903436A (es)
SE (2) SE445553B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9016799D0 (en) * 1990-07-31 1990-09-12 Shell Int Research Pesticidal heterocyclic compounds
BR112014028189A2 (pt) * 2012-05-18 2017-06-27 Sanofi Sa derivados de benzo[1,3]dioxina e seu uso como antagonistas de lpar5

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1312893A (fr) 1962-01-29 1962-12-21 Geigy Ag J R Nouveaux amides d'acides 1.4-benzodioxanne-carboxyliques et leur préparation
US3836543A (en) * 1970-10-14 1974-09-17 Richardson Merrell Inc Method of preparing dibenzo(d,g)(1,3)dioxocin acids and salts thereof
FR2146895B1 (es) * 1971-07-23 1974-09-06 Crt
US4046762A (en) * 1972-10-20 1977-09-06 Instituto Luso Farmaco D'italia S.R.L. Esters and amides of 3-aryl-1,4 benzodioxan-2-carboxylic acids
US4056540A (en) * 1974-01-01 1977-11-01 Bristol-Myers Company 4-Phenyl-1,3-benzodioxans
DE2508826A1 (de) * 1975-02-27 1976-09-09 Schering Ag Neue 1,3-benzodioxan-prostansaeurederivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DE2917902A1 (de) 1979-11-15
GB2022579A (en) 1979-12-19
SE7902817L (sv) 1979-11-04
JPS54144382A (en) 1979-11-10
CH640233A5 (fr) 1983-12-30
GB2022579B (en) 1982-09-15
NL7903436A (nl) 1979-11-06
DK180179A (da) 1979-11-04
IT1116836B (it) 1986-02-10
IT7948908A0 (it) 1979-05-02
SE445553B (sv) 1986-06-30
US4281012A (en) 1981-07-28

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