ES477162A1 - Procedimiento para la preparacion de corticoides. - Google Patents

Procedimiento para la preparacion de corticoides.

Info

Publication number
ES477162A1
ES477162A1 ES477162A ES477162A ES477162A1 ES 477162 A1 ES477162 A1 ES 477162A1 ES 477162 A ES477162 A ES 477162A ES 477162 A ES477162 A ES 477162A ES 477162 A1 ES477162 A1 ES 477162A1
Authority
ES
Spain
Prior art keywords
preparation
hydrogen
carbon atoms
chlorine
fluorine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES477162A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19782803661 external-priority patent/DE2803661A1/de
Priority claimed from DE19782855465 external-priority patent/DE2855465A1/de
Application filed by Schering AG filed Critical Schering AG
Publication of ES477162A1 publication Critical patent/ES477162A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0084—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkylene group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES477162A 1978-01-25 1979-01-25 Procedimiento para la preparacion de corticoides. Expired ES477162A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782803661 DE2803661A1 (de) 1978-01-25 1978-01-25 Neue in 17-position substituierte 11beta-hydroxysteroide der pregnanreihe, ihre herstellung und verwendung
DE19782855465 DE2855465A1 (de) 1978-12-19 1978-12-19 Neue kortikoide, verfahren zu ihrer herstellung, ihre verwendung und diese kortikoide enthaltende pharmazeutische praeparate

Publications (1)

Publication Number Publication Date
ES477162A1 true ES477162A1 (es) 1979-07-01

Family

ID=25773724

Family Applications (1)

Application Number Title Priority Date Filing Date
ES477162A Expired ES477162A1 (es) 1978-01-25 1979-01-25 Procedimiento para la preparacion de corticoides.

Country Status (21)

Country Link
US (1) US4207316A (ro)
EP (1) EP0003341B1 (ro)
AU (1) AU529292B2 (ro)
BG (3) BG33736A3 (ro)
CS (1) CS207753B2 (ro)
DD (2) DD141523A5 (ro)
DE (1) DE2967070D1 (ro)
DK (1) DK28779A (ro)
EG (1) EG14273A (ro)
ES (1) ES477162A1 (ro)
FI (1) FI66023C (ro)
FR (1) FR2422689A1 (ro)
GB (1) GB2014150B (ro)
IE (1) IE47729B1 (ro)
IL (1) IL56494A (ro)
NO (1) NO154583C (ro)
NZ (1) NZ189460A (ro)
PH (1) PH18164A (ro)
PT (1) PT69126A (ro)
RO (2) RO81116A (ro)
SU (6) SU876059A3 (ro)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2952003A1 (de) * 1979-12-21 1981-07-02 Schering Ag Berlin Und Bergkamen, 1000 Berlin Neue kortikoid-17-thioacetale, ihre herstellung und verwendung
DE3038855A1 (de) * 1980-10-10 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue d-homo-kortikoide, ihre herstellung und verwendung
KR960700266A (ko) * 1993-01-08 1996-01-19 클래스 빌헬름슨 신규 결장- 또는 회장-특이성 스테로이드 유도체(Novel Colon-or lleum-Specific Steroid Derivatives)
US5502222A (en) * 1994-06-01 1996-03-26 Schering Corporation Process for preparing delta 9,11 and 21-chloro corticosteroids
US8729108B2 (en) * 2008-06-17 2014-05-20 Christopher J Dannaker Waterborne topical compositions for the delivery of active ingredients such as azelaic acid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6682287D0 (pt) * 1965-08-30 1973-12-04 Merck & Co Inc Processo para preparar 17-alcoxi-progesteronas
NL6605514A (ro) * 1966-04-25 1967-10-26
US3453297A (en) * 1968-07-24 1969-07-01 Merck & Co Inc 17alpha-lower alkoxy-pregna-4,6-diene-3,20-dione steroids

Also Published As

Publication number Publication date
NO154583C (no) 1986-11-05
NO154583B (no) 1986-07-28
EG14273A (en) 1984-06-30
DK28779A (da) 1979-07-26
IL56494A0 (en) 1979-03-12
EP0003341A3 (en) 1979-08-22
IE47729B1 (en) 1984-05-30
DE2967070D1 (en) 1984-08-02
GB2014150A (en) 1979-08-22
PH18164A (en) 1985-04-09
IL56494A (en) 1983-02-23
AU4365779A (en) 1979-08-02
RO81116B (ro) 1983-05-30
RO81116A (ro) 1983-06-01
FI790240A (fi) 1979-07-26
CS207753B2 (en) 1981-08-31
GB2014150B (en) 1982-11-24
DD141523A5 (de) 1980-05-07
SU876059A3 (ru) 1981-10-23
SU927123A3 (ru) 1982-05-07
PT69126A (de) 1979-02-01
FI66023C (fi) 1984-08-10
FR2422689A1 (fr) 1979-11-09
DD150749A5 (de) 1981-09-16
IE790134L (en) 1979-07-25
FI66023B (fi) 1984-04-30
BG33737A3 (en) 1983-04-15
BG33736A3 (en) 1983-04-15
NO790229L (no) 1979-07-26
EP0003341A2 (de) 1979-08-08
SU876060A3 (ru) 1981-10-23
EP0003341B1 (de) 1984-06-27
US4207316A (en) 1980-06-10
NZ189460A (en) 1981-11-19
SU890979A3 (ru) 1981-12-15
AU529292B2 (en) 1983-06-02
BG33738A3 (en) 1983-04-15
SU880253A3 (ru) 1981-11-07
SU1103797A3 (ru) 1984-07-15
RO76163A (ro) 1981-08-17

Similar Documents

Publication Publication Date Title
IL72702A0 (en) Steroidal carboxylic acid esters,their manufacture and pharmaceutical compositions containing them
GR1001529B (el) Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
FI820281L (fi) Foerfarande foer framstaellning av 2-penemkompositioner med forfarandet framstaellda nya 2-penemkompositioner och dessa inehaollande farmaceutiska blandningar
NO304987B1 (no) Kortikosteroid-17-alkylkarbonat-21-[O]-karboksylsyre- og karbonsyreestere, legemidler inneholdende disse, samt anvendelse av forbindelsene
ES453853A1 (es) Metodo para producir nuevos derivados del acido fusidico.
ES477162A1 (es) Procedimiento para la preparacion de corticoides.
GB1121027A (en) New carboxylic acid derivatives, processes for the preparation thereof and compositions containing the same
DE69410419D1 (de) Quinolin-Carboxylsäurester von 21-Hydroxypregnan Derivaten und antibakterielle und entzüdungshemmende Präparate davon
ES477161A1 (es) Procedimiento para la preparacion de esteroides.
ES8506326A1 (es) Procedimiento para la preparacion de derivados de estrano y androstano
ES8405420A1 (es) Nuevo proceso para la preparacion de esteres de esteroides.
ES466794A1 (es) Un procedimiento para la preparacion de derivados de imida- zol.
GB1292785A (en) Derivatives of dexa- and beta-methasone, their production and use
GB1085080A (en) Benzoquinolizine and benzindolizine derivatives
IE782313L (en) Naphthalene derivatives
ES439852A1 (es) Un procedimiento para la preparacion de nuevos 17 alfa, 21- diesteres de 17 alfa, 21-dihidroxi-esteroides de la serie del pregnano.
IE780933L (en) Pregnene derivatives
DE3462400D1 (en) Carboxylic acid derivatives, processes for their production and pharmaceutical preparations containing them
ES8405033A1 (es) Procedimiento para la obtencion de esteroides dihalogenados.
JPS56120699A (en) 177aminoo166hydroxysteroid of novel androstane and estrane* its derivative and its drug composition
ES440690A1 (es) Procedimiento para la preparacion de d-homo-esteroides.
JPS5549400A (en) Novel 3 betaaaminoo2 betaahydroxysteroid of androstane*estrane and pregnanes*their manufacture and drug composition
ATE25089T1 (de) Androstene und verfahren zu ihrer herstellung.
GB1031746A (en) Improvements in or relating to steroids and the manufacture thereof
GB893142A (en) Improvements in or relating to steroids and the manufacture thereof