ES476266A1 - Procedimiento para la preparacion de diaminas ciclicas n,n'-disustituidas. - Google Patents

Procedimiento para la preparacion de diaminas ciclicas n,n'-disustituidas.

Info

Publication number
ES476266A1
ES476266A1 ES476266A ES476266A ES476266A1 ES 476266 A1 ES476266 A1 ES 476266A1 ES 476266 A ES476266 A ES 476266A ES 476266 A ES476266 A ES 476266A ES 476266 A1 ES476266 A1 ES 476266A1
Authority
ES
Spain
Prior art keywords
benzyl
disubstituted
preparing
same
cyclic diamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES476266A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES476266A1 publication Critical patent/ES476266A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Abstract

Procedimiento para la preparación de diaminas cíclicas N.N''-disustituidas de la fórmula **fórmula** o sus sales por adición de ácido con un ácido fisiloógicamente compatible, que se caracteriza porque se hace reaccionar a) N_-bencilpiperazina con ácido 5-metroxicumarílico, o con sus derivados activados a una temperatura de por lo menos 15ºC , o b) N-(5-metoxicumaroil)- piperazina con un halogenuro, alcohilsulfonato o arilsulfonato de bencilo.
ES476266A 1977-12-23 1978-12-22 Procedimiento para la preparacion de diaminas ciclicas n,n'-disustituidas. Expired ES476266A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772757532 DE2757532A1 (de) 1977-12-23 1977-12-23 N,n'-disubstituiertes cyclisches diamin und verfahren zu dessen herstellung

Publications (1)

Publication Number Publication Date
ES476266A1 true ES476266A1 (es) 1979-04-16

Family

ID=6027004

Family Applications (1)

Application Number Title Priority Date Filing Date
ES476266A Expired ES476266A1 (es) 1977-12-23 1978-12-22 Procedimiento para la preparacion de diaminas ciclicas n,n'-disustituidas.

Country Status (12)

Country Link
US (1) US4221793A (es)
EP (1) EP0018360B1 (es)
JP (1) JPS6045878B2 (es)
AT (1) AT366048B (es)
BE (1) BE873054A (es)
CA (1) CA1114380A (es)
DE (2) DE2757532A1 (es)
DK (1) DK282279A (es)
ES (1) ES476266A1 (es)
IT (1) IT1102430B (es)
NL (1) NL7812508A (es)
WO (1) WO1979000426A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791501A (fr) * 1971-11-19 1973-05-17 Albert Ag Chem Werke Diamines cycliques n,n'-disubstituees et leur procede de preparation
FR2475898A1 (fr) * 1980-02-14 1981-08-21 Andre Buzas Medicament analgesique contenant de la 1-(3'-benzofuryl)-4-benzylpiperazine et son procede de preparation
US4933351A (en) * 1983-10-31 1990-06-12 Merck Frosst Canada, Inc. Benzofuran 2-carbox amides useful as inhibitors of leukoriene biosynthesis
US4822803A (en) * 1983-10-31 1989-04-18 Merck Frosst Canada, Inc. Benzofuran 2-carboxylic acid hydrazides useful as inhibitors of leukotriene biosynthesis
EP0202580B1 (en) * 1985-05-13 1990-03-28 Kuraray Co., Ltd. 3,4-dihydrobenzopyran derivatives
US4937246A (en) * 1987-11-25 1990-06-26 Takeda Chemical Industries, Ltd. PAF antagonist, 1,4-disubstituted piperazine compounds and production thereof
JPH0536075U (ja) * 1991-10-17 1993-05-18 弘 市川 水車装置
DE19932314A1 (de) * 1999-07-10 2001-01-11 Merck Patent Gmbh Benzofuranderivate
KR101916701B1 (ko) 2014-09-26 2018-11-08 창저우 인셩 파마슈티칼 캄파니 리미티드 Ns4b 억제제인 벤조푸란 유사체

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115569A (en) * 1971-11-19 1978-09-19 Hoechst Aktiengesellschaft Cyclic diamine derivatives
BE791501A (fr) * 1971-11-19 1973-05-17 Albert Ag Chem Werke Diamines cycliques n,n'-disubstituees et leur procede de preparation

Also Published As

Publication number Publication date
US4221793A (en) 1980-09-09
AT366048B (de) 1982-03-10
EP0018360B1 (de) 1981-09-30
ATA917478A (de) 1981-07-15
DK282279A (da) 1979-07-12
IT1102430B (it) 1985-10-07
EP0018360A1 (de) 1980-11-12
BE873054A (fr) 1979-06-22
WO1979000426A1 (en) 1979-07-12
DE2861251D1 (en) 1981-12-10
IT7831298A0 (it) 1978-12-22
JPS6045878B2 (ja) 1985-10-12
DE2757532A1 (de) 1979-07-05
CA1114380A (en) 1981-12-15
JPS55500001A (es) 1980-01-10
NL7812508A (nl) 1979-06-26

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001