ES474449A1 - Procedimiento de obtencion de ureas y tioureas con actividad farmacologica. - Google Patents
Procedimiento de obtencion de ureas y tioureas con actividad farmacologica.Info
- Publication number
- ES474449A1 ES474449A1 ES474449A ES474449A ES474449A1 ES 474449 A1 ES474449 A1 ES 474449A1 ES 474449 A ES474449 A ES 474449A ES 474449 A ES474449 A ES 474449A ES 474449 A1 ES474449 A1 ES 474449A1
- Authority
- ES
- Spain
- Prior art keywords
- formulated
- ulcer
- gastric
- treatment
- atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000000767 anti-ulcer Effects 0.000 title 1
- 208000008469 Peptic Ulcer Diseases 0.000 abstract 2
- 230000002496 gastric effect Effects 0.000 abstract 2
- 208000012895 Gastric disease Diseases 0.000 abstract 1
- 208000007882 Gastritis Diseases 0.000 abstract 1
- 206010020601 Hyperchlorhydria Diseases 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 208000023652 chronic gastritis Diseases 0.000 abstract 1
- 206010009887 colitis Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 208000000718 duodenal ulcer Diseases 0.000 abstract 1
- 206010013864 duodenitis Diseases 0.000 abstract 1
- 201000005917 gastric ulcer Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000001272 neurogenic effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 208000011906 peptic ulcer disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000018556 stomach disease Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES474449A ES474449A1 (es) | 1978-10-23 | 1978-10-23 | Procedimiento de obtencion de ureas y tioureas con actividad farmacologica. |
IT69040/79A IT1121487B (it) | 1978-10-23 | 1979-10-19 | Procedimento per ottenere uree e tiouree dotate di attivita farmacologica |
FR7926179A FR2439772A1 (fr) | 1978-10-23 | 1979-10-22 | Procede de preparation d'urees et de thiourees utiles pour le traitement des ulceres gastrointestinaux et produits obtenus |
DE19792942564 DE2942564A1 (de) | 1978-10-23 | 1979-10-22 | Harnstoffe und thioharnstoffe |
JP54136933A JPS5823866B2 (ja) | 1978-10-23 | 1979-10-22 | ウレアおよびチオウレア誘導体 |
BE0/197758A BE879558A (fr) | 1978-10-23 | 1979-10-22 | Urees et thio-urees pharmacologiquement actives, leur preparation et leur utilisation |
GB7936757A GB2036555B (en) | 1978-10-23 | 1979-10-23 | Anti-ulcer conpositions |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES474449A ES474449A1 (es) | 1978-10-23 | 1978-10-23 | Procedimiento de obtencion de ureas y tioureas con actividad farmacologica. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES474449A1 true ES474449A1 (es) | 1979-05-01 |
Family
ID=8476971
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES474449A Expired ES474449A1 (es) | 1978-10-23 | 1978-10-23 | Procedimiento de obtencion de ureas y tioureas con actividad farmacologica. |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS5823866B2 (ja) |
BE (1) | BE879558A (ja) |
DE (1) | DE2942564A1 (ja) |
ES (1) | ES474449A1 (ja) |
FR (1) | FR2439772A1 (ja) |
GB (1) | GB2036555B (ja) |
IT (1) | IT1121487B (ja) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4460602A (en) * | 1981-06-30 | 1984-07-17 | The Procter & Gamble Company | Urea derivatives |
DE3132690A1 (de) * | 1981-08-19 | 1983-03-17 | Bayer Ag, 5090 Leverkusen | (thio)-harnstoffe, ein verfahren zu ihrer herstellung, ihre verwendung als pflanzenschutzmittel und zwischenprodukte zu ihrer herstellung |
US4879410A (en) * | 1986-11-03 | 1989-11-07 | American Cyanamid Company | Preparation of primary aralkyl urethanes and ureas and isocyanates derived therefrom |
GR880100400A (el) * | 1988-06-21 | 1990-05-11 | Sandoz Ag | Μεθοδος παρασκευης παραγωγων θειουριας |
HU206082B (en) * | 1988-12-23 | 1992-08-28 | Sandoz Ag | Process for producing capsaicin derivatives and pharmaceutical compositions comprising such compounds |
US5441984A (en) * | 1994-01-06 | 1995-08-15 | Eli Lilly And Company | Urea, thiourea and guanidine derivatives |
US5808151A (en) * | 1996-04-17 | 1998-09-15 | Bristol-Myers Squibb Company | Biphenylamido derivatives as melatonergic agents |
EP1749523A1 (en) * | 2005-07-29 | 2007-02-07 | Neuropharma, S.A. | GSK-3 inhibitors |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3090810A (en) * | 1961-01-11 | 1963-05-21 | Baxter Laboratories Inc | Benzyl thioureas |
US3164632A (en) * | 1963-02-04 | 1965-01-05 | Baxter Laboratories Inc | Benzyl ureas |
JPS49171A (ja) * | 1972-03-08 | 1974-01-05 | ||
ES461209A1 (es) * | 1977-07-30 | 1978-05-01 | Invest Tecnica Aplicada | Nuevo procedimiento para la preparacion de un derivado ben- cilico. |
-
1978
- 1978-10-23 ES ES474449A patent/ES474449A1/es not_active Expired
-
1979
- 1979-10-19 IT IT69040/79A patent/IT1121487B/it active
- 1979-10-22 FR FR7926179A patent/FR2439772A1/fr active Granted
- 1979-10-22 BE BE0/197758A patent/BE879558A/fr not_active IP Right Cessation
- 1979-10-22 JP JP54136933A patent/JPS5823866B2/ja not_active Expired
- 1979-10-22 DE DE19792942564 patent/DE2942564A1/de not_active Withdrawn
- 1979-10-23 GB GB7936757A patent/GB2036555B/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS5573652A (en) | 1980-06-03 |
FR2439772A1 (fr) | 1980-05-23 |
GB2036555A (en) | 1980-07-02 |
BE879558A (fr) | 1980-02-15 |
JPS5823866B2 (ja) | 1983-05-18 |
GB2036555B (en) | 1983-08-17 |
DE2942564A1 (de) | 1980-04-30 |
IT1121487B (it) | 1986-04-02 |
IT7969040A0 (it) | 1979-10-19 |
FR2439772B1 (ja) | 1984-03-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19991108 |