ES474321A1 - Procedimiento para la preparacion de alfa halometil deriva- dos de histamina y compuestos relacionados - Google Patents
Procedimiento para la preparacion de alfa halometil deriva- dos de histamina y compuestos relacionadosInfo
- Publication number
- ES474321A1 ES474321A1 ES474321A ES474321A ES474321A1 ES 474321 A1 ES474321 A1 ES 474321A1 ES 474321 A ES474321 A ES 474321A ES 474321 A ES474321 A ES 474321A ES 474321 A1 ES474321 A1 ES 474321A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- histamine
- alpha
- 4alkyl
- carbonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229960001340 histamine Drugs 0.000 title 1
- NTYJJOPFIAHURM-UHFFFAOYSA-N histamine Natural products NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000003143 4-hydroxybenzyl group Chemical group [H]C([*])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H] 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84365977A | 1977-10-19 | 1977-10-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES474321A1 true ES474321A1 (es) | 1980-01-16 |
Family
ID=25290634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES474321A Expired ES474321A1 (es) | 1977-10-19 | 1978-10-18 | Procedimiento para la preparacion de alfa halometil deriva- dos de histamina y compuestos relacionados |
Country Status (13)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1302919C (en) * | 1985-07-03 | 1992-06-09 | Robert T. Buckler | Histamine derivatives, immunogen conjugates and antibodies raised thereto |
| JPH0170657U (enrdf_load_stackoverflow) * | 1987-10-30 | 1989-05-11 | ||
| JP2009184686A (ja) * | 2008-02-04 | 2009-08-20 | Mitsubishi Heavy Industries Food & Packaging Machinery Co Ltd | ロータリー充填機及びロータリー充填機の充填方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE920250C (de) * | 1951-09-19 | 1954-11-18 | Hoffmann La Roche | Verfahren zur Herstellung von 4-(ª-Amino-ª-brompropyl)-imidazolsalzen |
| DE1161903B (de) * | 1960-08-19 | 1964-01-30 | Merck & Co Inc | Verfahren zur Herstellung von antihistaminisch wirksamem ª‡-Methyl-dl-histidin |
| FR1457259A (fr) * | 1961-08-18 | 1966-01-24 | Merck & Co Inc | Production d'amino-acides du type alpha-alkyl-histidine |
| IE46910B1 (en) * | 1977-06-01 | 1983-11-02 | Merck & Co Inc | Fluorinated alkylamines and process for preparing same |
-
1978
- 1978-09-25 ZA ZA00785435A patent/ZA785435B/xx unknown
- 1978-09-25 NZ NZ188498A patent/NZ188498A/xx unknown
- 1978-09-26 CA CA312,083A patent/CA1111432A/en not_active Expired
- 1978-10-10 DE DE19782844104 patent/DE2844104A1/de not_active Withdrawn
- 1978-10-10 NL NL7810173A patent/NL7810173A/xx not_active Application Discontinuation
- 1978-10-13 CH CH1066078A patent/CH637384A5/de not_active IP Right Cessation
- 1978-10-13 AU AU40706/78A patent/AU522245B2/en not_active Expired
- 1978-10-16 GB GB7840731A patent/GB2007231B/en not_active Expired
- 1978-10-17 IT IT51542/78A patent/IT1106448B/it active
- 1978-10-18 ES ES474321A patent/ES474321A1/es not_active Expired
- 1978-10-18 JP JP12746678A patent/JPS5466676A/ja active Granted
- 1978-10-18 BE BE191193A patent/BE871356A/xx not_active IP Right Cessation
- 1978-10-18 FR FR7829697A patent/FR2406631A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| NZ188498A (en) | 1980-08-26 |
| IT7851542A0 (it) | 1978-10-17 |
| GB2007231A (en) | 1979-05-16 |
| CH637384A5 (de) | 1983-07-29 |
| AU522245B2 (en) | 1982-05-27 |
| BE871356A (fr) | 1979-02-15 |
| NL7810173A (nl) | 1979-04-23 |
| JPS5466676A (en) | 1979-05-29 |
| FR2406631A1 (fr) | 1979-05-18 |
| ZA785435B (en) | 1979-09-26 |
| AU4070678A (en) | 1980-04-17 |
| JPS6223753B2 (enrdf_load_stackoverflow) | 1987-05-25 |
| GB2007231B (en) | 1982-03-24 |
| DE2844104A1 (de) | 1979-04-26 |
| IT1106448B (it) | 1985-11-11 |
| CA1111432A (en) | 1981-10-27 |
| FR2406631B1 (enrdf_load_stackoverflow) | 1980-09-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19991108 |