ES473909A1 - Procedimiento para la obtencion de derivados del acido ci- clohexil-4 naftaleno-acetico-1 - Google Patents
Procedimiento para la obtencion de derivados del acido ci- clohexil-4 naftaleno-acetico-1Info
- Publication number
- ES473909A1 ES473909A1 ES473909A ES473909A ES473909A1 ES 473909 A1 ES473909 A1 ES 473909A1 ES 473909 A ES473909 A ES 473909A ES 473909 A ES473909 A ES 473909A ES 473909 A1 ES473909 A1 ES 473909A1
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- naphthalene
- cyclohexyl
- drugs
- acetic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/32—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by introduction of halogenated alkyl groups into ring compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procedimiento para la obtención de derivados del ácido ciclohexil-4-naftaleno-acético-1, caracterizado porque consiste en bloquear la función ácida del ácido ciclo-hexil-4-naftaleno-acético-1 utilizado como materia de partida, en tratar el compuesto resultante con yoduro de alquilo de fórmula RI o R y, seguidamente, en liberar la función ácida por saponificación del compuesto así obtenido después de acidificación, consiguiéndose un producto que responde a la fórmula general: **(Fórmula)** en la que R es un grupo alquilo inferior, y del que sus sales y derivados son farmacéuticamente aceptables.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7729728A FR2404620A2 (fr) | 1977-10-03 | 1977-10-03 | Derives de l'acide cyclohexyl-4 naphtalene acetique-1, procede d'obtention et application a titre de medicament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES473909A1 true ES473909A1 (es) | 1979-04-01 |
Family
ID=9196050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES473909A Expired ES473909A1 (es) | 1977-10-03 | 1978-10-03 | Procedimiento para la obtencion de derivados del acido ci- clohexil-4 naftaleno-acetico-1 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4218473A (es) |
| JP (1) | JPS5461161A (es) |
| AT (1) | AT356089B (es) |
| AU (1) | AU521195B2 (es) |
| BE (1) | BE870553A (es) |
| CA (1) | CA1100527A (es) |
| CH (1) | CH635307A5 (es) |
| DE (1) | DE2842495C2 (es) |
| DK (1) | DK150846C (es) |
| ES (1) | ES473909A1 (es) |
| FI (1) | FI65424C (es) |
| FR (1) | FR2404620A2 (es) |
| GB (1) | GB2006763B (es) |
| GR (1) | GR66032B (es) |
| NL (2) | NL185143C (es) |
| PT (1) | PT68611A (es) |
| SE (1) | SE442993B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103183604B (zh) * | 2011-12-28 | 2015-07-29 | 药源药物化学（上海）有限公司 | 维达洛芬的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3904682A (en) * | 1967-01-13 | 1975-09-09 | Syntex Corp | 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid |
| US3896157A (en) * | 1967-01-13 | 1975-07-22 | Syntex Corp | Dihydo 2-naphthylacetic acid derivatives |
| FR2115026B1 (es) * | 1970-11-24 | 1974-03-22 | Logeais Labor Jacques |
-
1977
- 1977-10-03 FR FR7729728A patent/FR2404620A2/fr active Granted
-
1978
- 1978-09-18 BE BE190544A patent/BE870553A/xx not_active IP Right Cessation
- 1978-09-26 US US05/945,891 patent/US4218473A/en not_active Expired - Lifetime
- 1978-09-28 AU AU40266/78A patent/AU521195B2/en not_active Expired
- 1978-09-29 DE DE2842495A patent/DE2842495C2/de not_active Expired
- 1978-09-29 GR GR57337A patent/GR66032B/el unknown
- 1978-09-29 DK DK432478A patent/DK150846C/da not_active IP Right Cessation
- 1978-10-02 PT PT68611A patent/PT68611A/pt unknown
- 1978-10-02 CH CH1021378A patent/CH635307A5/fr not_active IP Right Cessation
- 1978-10-02 NL NLAANVRAGE7809949,A patent/NL185143C/xx not_active IP Right Cessation
- 1978-10-02 JP JP12142378A patent/JPS5461161A/ja active Granted
- 1978-10-02 SE SE7810294A patent/SE442993B/sv not_active IP Right Cessation
- 1978-10-02 FI FI782993A patent/FI65424C/fi not_active IP Right Cessation
- 1978-10-02 CA CA312,498A patent/CA1100527A/fr not_active Expired
- 1978-10-03 ES ES473909A patent/ES473909A1/es not_active Expired
- 1978-10-03 GB GB7839192A patent/GB2006763B/en not_active Expired
- 1978-10-03 AT AT713578A patent/AT356089B/de not_active IP Right Cessation
-
1996
- 1996-03-05 NL NL960003C patent/NL960003I2/nl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI65424C (fi) | 1984-05-10 |
| CH635307A5 (fr) | 1983-03-31 |
| NL7809949A (nl) | 1979-04-05 |
| DK432478A (da) | 1979-04-04 |
| DK150846C (da) | 1988-02-01 |
| SE7810294L (sv) | 1979-04-04 |
| AU4026678A (en) | 1980-04-03 |
| US4218473A (en) | 1980-08-19 |
| AT356089B (de) | 1980-04-10 |
| DE2842495C2 (de) | 1983-05-19 |
| GB2006763A (en) | 1979-05-10 |
| DK150846B (da) | 1987-07-06 |
| NL960003I2 (nl) | 1996-11-01 |
| CA1100527A (fr) | 1981-05-05 |
| PT68611A (fr) | 1978-11-01 |
| NL185143C (nl) | 1990-02-01 |
| ATA713578A (de) | 1979-09-15 |
| DE2842495A1 (de) | 1979-04-19 |
| SE442993B (sv) | 1986-02-10 |
| GB2006763B (en) | 1982-03-17 |
| BE870553A (fr) | 1979-03-19 |
| FR2404620A2 (fr) | 1979-04-27 |
| JPS5640140B2 (es) | 1981-09-18 |
| FR2404620B2 (es) | 1980-08-01 |
| NL185143B (nl) | 1989-09-01 |
| AU521195B2 (en) | 1982-03-18 |
| JPS5461161A (en) | 1979-05-17 |
| FI65424B (fi) | 1984-01-31 |
| GR66032B (es) | 1981-01-14 |
| NL960003I1 (nl) | 1996-05-01 |
| FI782993A (fi) | 1979-04-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990222 |