ES471674A1 - Un procedimiento para la preparacion de derivados del indol - Google Patents

Un procedimiento para la preparacion de derivados del indol

Info

Publication number
ES471674A1
ES471674A1 ES471674A ES471674A ES471674A1 ES 471674 A1 ES471674 A1 ES 471674A1 ES 471674 A ES471674 A ES 471674A ES 471674 A ES471674 A ES 471674A ES 471674 A1 ES471674 A1 ES 471674A1
Authority
ES
Spain
Prior art keywords
alkyl
optionally
carboxamido
substituents
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES471674A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES471674A1 publication Critical patent/ES471674A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ES471674A 1977-07-13 1978-07-12 Un procedimiento para la preparacion de derivados del indol Expired ES471674A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81513877A 1977-07-13 1977-07-13

Publications (1)

Publication Number Publication Date
ES471674A1 true ES471674A1 (es) 1979-10-01

Family

ID=25216976

Family Applications (1)

Application Number Title Priority Date Filing Date
ES471674A Expired ES471674A1 (es) 1977-07-13 1978-07-12 Un procedimiento para la preparacion de derivados del indol

Country Status (30)

Country Link
JP (1) JPS5419972A (no)
AR (1) AR225274A1 (no)
AT (1) AT364821B (no)
AU (1) AU525064B2 (no)
BE (1) BE868943A (no)
CA (1) CA1116598A (no)
CH (1) CH642066A5 (no)
CY (1) CY1274A (no)
DE (1) DE2830884A1 (no)
DK (1) DK156568C (no)
ES (1) ES471674A1 (no)
FI (1) FI69835C (no)
FR (1) FR2397404A1 (no)
GB (1) GB2001633B (no)
GR (1) GR74488B (no)
HK (1) HK1385A (no)
HU (1) HU178992B (no)
IE (1) IE47122B1 (no)
IL (1) IL55115A (no)
IT (1) IT1105091B (no)
KE (1) KE3485A (no)
LU (1) LU79966A1 (no)
MY (1) MY8500946A (no)
NL (1) NL189946C (no)
NO (1) NO149311C (no)
NZ (1) NZ187763A (no)
SE (1) SE429339B (no)
SG (1) SG82584G (no)
YU (1) YU40528B (no)
ZA (1) ZA783744B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire
US4321398A (en) * 1981-05-07 1982-03-23 Mead Johnson & Company Thienyl and benzothienyl-tertiary butylaminophenoxypropanols
DE3119796A1 (de) * 1981-05-19 1982-12-23 Hoechst Ag, 6000 Frankfurt Substituierte tryptaminderivate von thienyloxpropanolaminen, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen sowie ihre verwendung
FR2523964B1 (fr) * 1982-03-23 1985-09-27 Sanofi Sa Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation
NZ208337A (en) * 1983-06-10 1988-10-28 Bristol Myers Co 2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions
FR2601008B1 (fr) * 1986-07-03 1990-03-30 Sanofi Sa Procede de synthese stereospecifique de derives de l'indole
JP2004513164A (ja) 2000-11-10 2004-04-30 イーライ・リリー・アンド・カンパニー ３−置換オキシインドールβ３アゴニスト
WO2003016276A2 (en) 2001-08-14 2003-02-27 Eli Lilly And Company 3-substituted oxindole beta-3 agonists
ATE340794T1 (de) 2001-08-14 2006-10-15 Lilly Co Eli Indol derivate als beta-3-adrenerge agonisten zur behandlung von typ 2 diabetes
AU2002353844A1 (en) 2001-11-20 2003-06-10 Eli Lilly And Company Beta 3 adrenergic agonists
US7205407B2 (en) 2001-11-20 2007-04-17 Eli Lilly And Company 3-Substituted oxindole β3 agonists
AU2002357084A1 (en) 2002-01-11 2003-07-30 Eli Lilly And Company 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as beta3 agonists
US8946284B2 (en) 2008-08-01 2015-02-03 Arca Biopharma, Inc. Methods and compositions involving (S)-bucindolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1532210A (fr) * 1963-06-21 1968-07-12 Ici Ltd Composés hétérocycliques et leur procédé de préparation
CH495983A (de) * 1968-02-09 1970-09-15 Sandoz Ag Verfahren zur Herstellung von linksdrehendem 4-(2-Hydroxy-3-isopropylaminopropoxy)indol
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
US3946009A (en) * 1972-05-05 1976-03-23 Merck Sharp & Dohme (I.A.) Corporation 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines

Also Published As

Publication number Publication date
YU40528B (en) 1986-02-28
AU3770478A (en) 1980-01-10
NO782407L (no) 1979-01-16
GB2001633B (en) 1982-03-24
FI69835B (fi) 1985-12-31
CY1274A (en) 1985-03-08
IT1105091B (it) 1985-10-28
IL55115A (en) 1981-09-13
HU178992B (en) 1982-07-28
AR225274A1 (es) 1982-03-15
DK156568C (da) 1990-02-05
YU161178A (en) 1983-02-28
NZ187763A (en) 1984-07-31
NL7807564A (nl) 1979-01-16
FR2397404B1 (no) 1982-06-11
IE781400L (en) 1979-01-13
ZA783744B (en) 1979-07-25
LU79966A1 (fr) 1979-04-09
IL55115A0 (en) 1978-09-29
KE3485A (en) 1985-01-25
HK1385A (en) 1985-01-11
SE429339B (sv) 1983-08-29
DK156568B (da) 1989-09-11
MY8500946A (en) 1985-12-31
BE868943A (fr) 1979-01-12
DE2830884C2 (no) 1990-01-11
DE2830884A1 (de) 1979-02-01
GR74488B (no) 1984-06-28
ATA508978A (de) 1981-04-15
NL189946C (nl) 1993-09-16
AT364821B (de) 1981-11-25
NO149311C (no) 1984-03-28
NL189946B (nl) 1993-04-16
SG82584G (en) 1985-09-13
FI782205A (fi) 1979-01-14
DK313878A (da) 1979-01-14
IE47122B1 (en) 1983-12-28
IT7850228A0 (it) 1978-07-10
FI69835C (fi) 1986-05-26
CA1116598A (en) 1982-01-19
JPS6340784B2 (no) 1988-08-12
AU525064B2 (en) 1982-10-21
JPS5419972A (en) 1979-02-15
NO149311B (no) 1983-12-19
FR2397404A1 (fr) 1979-02-09
GB2001633A (en) 1979-02-07
SE7807700L (sv) 1979-01-14
CH642066A5 (de) 1984-03-30

Similar Documents

Publication Publication Date Title
DE3587568D1 (de) Diazepine enthaltende pharmazeutische Zusammensetzungen mit Plättchen aktivierender Faktor (PAF)-antagonistischer Wirkung.
ES471674A1 (es) Un procedimiento para la preparacion de derivados del indol
ES8201965A1 (es) Un metodo de preparacion de compuestos de sulfonilo
ES8304944A1 (es) Un procedimiento para la preparacion de derivados de aminopirimidina.
ES8406419A1 (es) Un procedimiento para la preparacion de derivados de areno y hetero-arenocarboxamidas
IE780235L (en) Aryl sulphonates, herbicides
ES552702A1 (es) Procedimiento para la preparacion de nuevas (hetero)-aril-propilaminas
MY104174A (en) Insecticidal compounds.
ES444870A1 (es) Procedimiento para preparar derivados de oxadiazolinona.
AR245699A1 (es) Compuestos derivados de n'-alquil-n,n'-diacilhidrazinas insecticidamente activos y composicion que los comprende.
ES458557A1 (es) Un procedimiento de preparacion de derivados de quinazolina.
ES479040A1 (es) Procedimiento para preparar cetoximinoeteres.
DE69416683D1 (de) Benzolactam-derivate
ES428346A1 (es) Procedimiento para preparar un ester fosforico derivado de la pirazolina.
ES476263A1 (es) Un procedimiento para la preparacion de esteres fosforicos y tiofosforicos de 5(3)-hidroxipirazoles.
ES463162A1 (es) Procedimiento para la obtencion de derivados de 4,5-dicloro-imidazol.
IE780426L (en) Oxadiazole derivatives
IL98987A (en) Heterocyclic compounds their preparation and their use as pesticides
ATE53381T1 (de) Dihaloformaldoxime.
ES416988A1 (es) Procedimiento para la obtencion de 2-amino-4 h-piranos.
ES8105966A1 (es) Procedimiento para la preparacion de nuevos derivados nitro-alcanoles y de agentes fitoprotectores que los contienen
TW337983B (en) 1, 3-oxazn-4-one derivatives, their preparation and uses
ES468532A1 (es) Un procedimiento para preparar un compuesto de sulfonio re- gulador del crecimiento de las plantas
ES457260A1 (es) Procedimiento de preparacion de nuevos derivados del ditie- pino(1,4)(2,3-c) pirrol.
TH8125A (th) สารกำจัดเชื้อราประเภทอาคริลเลท