ES469004A1 - Un procedimiento para la preparacion de nuevos derivados de somatostatina - Google Patents
Un procedimiento para la preparacion de nuevos derivados de somatostatinaInfo
- Publication number
- ES469004A1 ES469004A1 ES469004A ES469004A ES469004A1 ES 469004 A1 ES469004 A1 ES 469004A1 ES 469004 A ES469004 A ES 469004A ES 469004 A ES469004 A ES 469004A ES 469004 A1 ES469004 A1 ES 469004A1
- Authority
- ES
- Spain
- Prior art keywords
- phe
- hydrogen
- cys
- thr
- lys
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000006239 protecting group Chemical group 0.000 abstract 3
- QNAYBMKLOCPYGJ-UWTATZPHSA-N D-alanine Chemical group C[C@@H](N)C(O)=O QNAYBMKLOCPYGJ-UWTATZPHSA-N 0.000 abstract 2
- 125000003558 D-valino group Chemical group C(=O)(O)[C@@H](C(C)C)N* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 abstract 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78947377A | 1977-04-21 | 1977-04-21 | |
| US04/874,173 US4151394A (en) | 1978-02-01 | 1978-02-01 | Guidance system for arc welder |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES469004A1 true ES469004A1 (es) | 1979-09-01 |
Family
ID=27120917
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES469004A Expired ES469004A1 (es) | 1977-04-21 | 1978-04-20 | Un procedimiento para la preparacion de nuevos derivados de somatostatina |
| ES476913A Expired ES476913A1 (es) | 1977-04-21 | 1979-01-16 | Un procedimiento para la preparacion de nuevos derivados de somatostatina. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES476913A Expired ES476913A1 (es) | 1977-04-21 | 1979-01-16 | Un procedimiento para la preparacion de nuevos derivados de somatostatina. |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS53132589A (da) |
| AR (1) | AR229798A1 (da) |
| AT (1) | AT360675B (da) |
| AU (1) | AU518731B2 (da) |
| BG (2) | BG28705A4 (da) |
| CA (1) | CA1120030A (da) |
| CH (1) | CH634040A5 (da) |
| DD (1) | DD136739A5 (da) |
| DE (1) | DE2816855A1 (da) |
| DK (1) | DK174178A (da) |
| EG (1) | EG14800A (da) |
| ES (2) | ES469004A1 (da) |
| FI (1) | FI64575C (da) |
| FR (1) | FR2387942A1 (da) |
| GB (1) | GB1596329A (da) |
| GR (1) | GR69789B (da) |
| IE (1) | IE46617B1 (da) |
| IL (1) | IL54532A (da) |
| IT (1) | IT1094471B (da) |
| NL (1) | NL7804219A (da) |
| NZ (1) | NZ187010A (da) |
| PT (1) | PT67912B (da) |
| SE (1) | SE7804398L (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8423431D0 (en) * | 1984-09-17 | 1984-10-24 | Sandoz Ltd | Organic compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2608336A1 (de) * | 1975-03-11 | 1976-09-30 | Sandoz Ag | Neue organische verbindungen, ihre herstellung und verwendung |
| US4372884A (en) * | 1975-08-06 | 1983-02-08 | The Salk Institute For Biological Studies | Pharmaceutically active peptides |
-
1978
- 1978-04-17 GB GB14917/78A patent/GB1596329A/en not_active Expired
- 1978-04-18 FI FI781183A patent/FI64575C/fi not_active IP Right Cessation
- 1978-04-18 PT PT67912A patent/PT67912B/pt unknown
- 1978-04-18 SE SE7804398A patent/SE7804398L/xx unknown
- 1978-04-18 DE DE19782816855 patent/DE2816855A1/de not_active Withdrawn
- 1978-04-18 AR AR271821A patent/AR229798A1/es active
- 1978-04-18 JP JP4621478A patent/JPS53132589A/ja active Pending
- 1978-04-18 IL IL54532A patent/IL54532A/xx unknown
- 1978-04-18 NZ NZ187010A patent/NZ187010A/xx unknown
- 1978-04-19 FR FR7811581A patent/FR2387942A1/fr active Granted
- 1978-04-19 IE IE766/78A patent/IE46617B1/en unknown
- 1978-04-19 EG EG265/78A patent/EG14800A/xx active
- 1978-04-19 GR GR56031A patent/GR69789B/el unknown
- 1978-04-19 CA CA000301485A patent/CA1120030A/en not_active Expired
- 1978-04-20 NL NL7804219A patent/NL7804219A/xx not_active Application Discontinuation
- 1978-04-20 AT AT282978A patent/AT360675B/de not_active IP Right Cessation
- 1978-04-20 DK DK174178A patent/DK174178A/da active IP Right Grant
- 1978-04-20 ES ES469004A patent/ES469004A1/es not_active Expired
- 1978-04-20 IT IT22553/78A patent/IT1094471B/it active
- 1978-04-20 CH CH425878A patent/CH634040A5/de not_active IP Right Cessation
- 1978-04-21 BG BG040964A patent/BG28705A4/xx unknown
- 1978-04-21 BG BG039504A patent/BG28704A3/xx unknown
- 1978-04-21 AU AU35341/78A patent/AU518731B2/en not_active Expired
- 1978-04-21 DD DD78204949A patent/DD136739A5/xx unknown
-
1979
- 1979-01-16 ES ES476913A patent/ES476913A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IE46617B1 (en) | 1983-08-10 |
| JPS53132589A (en) | 1978-11-18 |
| NZ187010A (en) | 1980-08-26 |
| FI64575C (fi) | 1983-12-12 |
| IT7822553A0 (it) | 1978-04-20 |
| GB1596329A (en) | 1981-08-26 |
| FI781183A7 (fi) | 1978-10-22 |
| SE7804398L (sv) | 1978-10-22 |
| AU518731B2 (en) | 1981-10-15 |
| DK174178A (da) | 1978-10-22 |
| ATA282978A (de) | 1980-06-15 |
| PT67912A (en) | 1978-05-01 |
| DD136739A5 (de) | 1979-07-25 |
| AU3534178A (en) | 1979-10-25 |
| IE780766L (en) | 1978-10-21 |
| GR69789B (da) | 1982-07-07 |
| BG28704A3 (bg) | 1980-06-16 |
| IL54532A (en) | 1983-03-31 |
| PT67912B (en) | 1979-11-14 |
| AR229798A1 (es) | 1983-11-30 |
| FR2387942B1 (da) | 1981-06-26 |
| IL54532A0 (en) | 1978-07-31 |
| CH634040A5 (en) | 1983-01-14 |
| AT360675B (de) | 1981-01-26 |
| CA1120030A (en) | 1982-03-16 |
| BG28705A4 (bg) | 1980-06-16 |
| FR2387942A1 (fr) | 1978-11-17 |
| DE2816855A1 (de) | 1978-11-02 |
| IT1094471B (it) | 1985-08-02 |
| FI64575B (fi) | 1983-08-31 |
| NL7804219A (nl) | 1978-10-24 |
| ES476913A1 (es) | 1979-09-16 |
| EG14800A (en) | 1985-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8101077A1 (es) | Procedimiento para preparar acidos 3-cefem-4-carboxilicos sustituidos en la posicion 7 | |
| ES2072959T3 (es) | Derivados de aminoacido. | |
| ES2031569T3 (es) | Derivados de acidos quinolinocarboxilicos. | |
| ES485066A1 (es) | Un procedimiento para preparar derivados de piridina o piri-midina | |
| ES8202015A1 (es) | Un procedimiento para la preparacion de derivados de penici-lina | |
| ES2081817T3 (es) | Polipeptido con secuencias principales repetidas que se fijan en la celula. | |
| ES472847A1 (es) | Procedimiento para la preparacion de la 2-bromoergosina y sus sales acidas de adicion | |
| SE7411243L (da) | ||
| ES2012736A6 (es) | Procedimiento para la preparacion de derivados triciclicos de 3-oxopropanonitrilo. | |
| SE7902866L (sv) | 3-0-(beta-d-glukuronopyranosyl)-sojasapogenol b | |
| ES455691A1 (es) | Procedimiento para la produccion de derivados de piperacina. | |
| ES469004A1 (es) | Un procedimiento para la preparacion de nuevos derivados de somatostatina | |
| SE7609909L (sv) | Nya penicilliner och forfarande for framstellning derav | |
| SE7708626L (sv) | Sett att framstella oximderivat av 3-karbamoyloximetyl-7-aminotiazolyl-acetamidocefalosporansyra | |
| ES2054186T3 (es) | Composicion antihepatopatica. | |
| ES8400238A1 (es) | "un procedimiento para la preparacion de soluciones acuosas de sulfonamidas potenciales". | |
| ES8504182A1 (es) | Procedimiento para preparar nuevos derivados de piperidina | |
| ATE30582T1 (de) | Ungesaettigte arylalkylammoniumsalze. | |
| IT1160387B (it) | Derivato isossazolico, ad attivita' terapeutica | |
| ES449991A1 (es) | Procedimiento para la preparacion de derivados de acido 7 (alfaamino-omega-(2,3-metilenodioxifenil y acilamido) cefa- losporanico. | |
| GB1533129A (en) | Process for producing a peptide in the presence of an enzyme | |
| GB1115930A (en) | An indolyl vindoline and process for preparing the same | |
| ES469206A1 (es) | Un procedimiento para preparar acido 7 b-haloarilmalonamido-7-metoxi-3-tiometil heterociclico-1-destia-1-oxa-3-cefem-4- carboxilico | |
| ES546646A0 (es) | Un procedimiento para preparar un compuesto relacionado con arfamenina | |
| ES8303405A1 (es) | Procedimiento de preparacion de derivados de quinidina. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20000301 |