ES466587A1 - Un procedimiento para la preparacion de nuevos derivados de bencenosulfonamida y bencenocarboxamida - Google Patents
Un procedimiento para la preparacion de nuevos derivados de bencenosulfonamida y bencenocarboxamidaInfo
- Publication number
- ES466587A1 ES466587A1 ES466587A ES466587A ES466587A1 ES 466587 A1 ES466587 A1 ES 466587A1 ES 466587 A ES466587 A ES 466587A ES 466587 A ES466587 A ES 466587A ES 466587 A1 ES466587 A1 ES 466587A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- hydrogen
- alkyl
- general formula
- benzensulfonamido
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 benzensulfonamido Chemical group 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- KHBQMWCZKVMBLN-UHFFFAOYSA-N Benzenesulfonamide Chemical compound NS(=O)(=O)C1=CC=CC=C1 KHBQMWCZKVMBLN-UHFFFAOYSA-N 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 229910006074 SO2NH2 Inorganic materials 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000003936 benzamides Chemical class 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000005113 hydroxyalkoxy group Chemical group 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 238000005932 reductive alkylation reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000565 sulfonamide group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB442077 | 1977-02-03 | ||
| GB4419/77A GB1593651A (en) | 1977-02-03 | 1977-02-03 | Amides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES466587A1 true ES466587A1 (es) | 1979-01-16 |
Family
ID=26239110
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES466587A Expired ES466587A1 (es) | 1977-02-03 | 1978-02-02 | Un procedimiento para la preparacion de nuevos derivados de bencenosulfonamida y bencenocarboxamida |
| ES475157A Expired ES475157A1 (es) | 1977-02-03 | 1978-11-16 | Un procedimiento para la preparacion de nuevos derivados de bencenosulfonamida y bencenocarboxamina. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES475157A Expired ES475157A1 (es) | 1977-02-03 | 1978-11-16 | Un procedimiento para la preparacion de nuevos derivados de bencenosulfonamida y bencenocarboxamina. |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS6011898B2 (da) |
| AU (1) | AU521707B2 (da) |
| CH (1) | CH642057A5 (da) |
| DE (1) | DE2803688A1 (da) |
| DK (1) | DK31578A (da) |
| ES (2) | ES466587A1 (da) |
| FR (1) | FR2379515A1 (da) |
| NL (1) | NL7801216A (da) |
| NZ (1) | NZ186310A (da) |
| SE (1) | SE7800930L (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1147342A (en) * | 1977-10-12 | 1983-05-31 | Kazuo Imai | Process of producing novel phenylethanolamine derivatives |
| JPS5553262A (en) * | 1978-10-17 | 1980-04-18 | Yamanouchi Pharmaceut Co Ltd | Phenylethanolamine derivative |
| EP0028105B1 (en) * | 1979-10-25 | 1983-01-19 | Beecham Group Plc | Secondary amines, their preparation and use in pharmaceutical compositions |
| PH25150A (en) * | 1986-06-05 | 1991-03-13 | Ciba Geigy Ag | Novel pharmaceutical preparation for topical application |
| US4906634A (en) * | 1988-03-08 | 1990-03-06 | Schering A.G. | Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents |
| AU2737295A (en) * | 1994-06-09 | 1996-01-04 | Glaxo Group Limited | Phenethanolamine derivatives and their use as atypical beta-adrenoceptor agonists |
| ZA964425B (en) * | 1995-07-05 | 1996-12-09 | De Beers Ind Diamond | Mounting of cutter picks |
| CN1083831C (zh) * | 1996-01-10 | 2002-05-01 | 旭化成株式会社 | 新的三环化合物及含有它们的药物组合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1266058A (da) * | 1969-07-08 | 1972-03-08 | ||
| US3860647A (en) * | 1973-08-20 | 1975-01-14 | Smithkline Corp | {60 -Aminomethyl-4-hydroxy-3-sulfamyl-benzyl alcohols and 4-hydroxy-3-sulfamyl phenethylamines |
| LU74760A1 (da) * | 1975-04-17 | 1977-02-04 |
-
1978
- 1978-01-20 DK DK31578A patent/DK31578A/da not_active Application Discontinuation
- 1978-01-25 NZ NZ186310A patent/NZ186310A/xx unknown
- 1978-01-25 AU AU32731/78A patent/AU521707B2/en not_active Expired
- 1978-01-25 SE SE7800930A patent/SE7800930L/xx unknown
- 1978-01-27 DE DE19782803688 patent/DE2803688A1/de not_active Withdrawn
- 1978-01-30 CH CH96678A patent/CH642057A5/de not_active IP Right Cessation
- 1978-02-02 NL NL7801216A patent/NL7801216A/xx not_active Application Discontinuation
- 1978-02-02 ES ES466587A patent/ES466587A1/es not_active Expired
- 1978-02-03 FR FR7803114A patent/FR2379515A1/fr active Granted
- 1978-02-03 JP JP53011390A patent/JPS6011898B2/ja not_active Expired
- 1978-11-16 ES ES475157A patent/ES475157A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2379515A1 (fr) | 1978-09-01 |
| DK31578A (da) | 1978-08-04 |
| SE7800930L (sv) | 1978-08-04 |
| JPS6011898B2 (ja) | 1985-03-28 |
| ES475157A1 (es) | 1979-05-01 |
| JPS53111029A (en) | 1978-09-28 |
| NZ186310A (en) | 1979-10-25 |
| DE2803688A1 (de) | 1978-08-10 |
| NL7801216A (nl) | 1978-08-07 |
| AU521707B2 (en) | 1982-04-29 |
| CH642057A5 (en) | 1984-03-30 |
| AU3273178A (en) | 1979-08-02 |
| FR2379515B1 (da) | 1981-07-31 |
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