ES465939A1 - Procedimiento para preparar derivados de la meta-trifluome- tilfenil-perazina. - Google Patents
Procedimiento para preparar derivados de la meta-trifluome- tilfenil-perazina.Info
- Publication number
- ES465939A1 ES465939A1 ES465939A ES465939A ES465939A1 ES 465939 A1 ES465939 A1 ES 465939A1 ES 465939 A ES465939 A ES 465939A ES 465939 A ES465939 A ES 465939A ES 465939 A1 ES465939 A1 ES 465939A1
- Authority
- ES
- Spain
- Prior art keywords
- cycloalkyl
- carbon atoms
- piperazino
- alkyl group
- region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C07D295/116—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings with the doubly bound oxygen or sulfur atoms directly attached to a carbocyclic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1539/77A GB1560271A (en) | 1977-01-14 | 1977-01-14 | Therapeutically useful m-trifluoromethylphenylpiperazine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES465939A1 true ES465939A1 (es) | 1978-09-16 |
Family
ID=9723745
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES465939A Expired ES465939A1 (es) | 1977-01-14 | 1978-01-13 | Procedimiento para preparar derivados de la meta-trifluome- tilfenil-perazina. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4203986A (enExample) |
| JP (1) | JPS5439085A (enExample) |
| AU (1) | AU512266B2 (enExample) |
| BE (1) | BE867030A (enExample) |
| DE (1) | DE2800954A1 (enExample) |
| ES (1) | ES465939A1 (enExample) |
| FI (1) | FI780034A7 (enExample) |
| FR (1) | FR2377392A1 (enExample) |
| GB (1) | GB1560271A (enExample) |
| IT (1) | IT7823355A0 (enExample) |
| LU (1) | LU79968A1 (enExample) |
| NZ (1) | NZ186189A (enExample) |
| SE (1) | SE7806466L (enExample) |
| ZA (1) | ZA78124B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4518712A (en) * | 1980-06-30 | 1985-05-21 | Taiho Pharmaceutical Company Limited | Piperazine derivative and analgesic composition containing the same |
| DE3306964A1 (de) * | 1983-02-28 | 1984-09-06 | Boehringer Ingelheim KG, 6507 Ingelheim | Neues n-arylpiperazin und verfahren zu seiner herstellung |
| FI864570A0 (fi) * | 1986-11-11 | 1986-11-11 | Farmos Oy | Terapeutiskt anvaendbar foerening. |
| US4882330A (en) * | 1986-11-21 | 1989-11-21 | A. H. Robins Company, Incorporated | 1-aryloxy-4-[((4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents |
| DK78692D0 (da) * | 1992-06-12 | 1992-06-12 | Lundbeck & Co As H | Dimere piperidin- og piperazinderivater |
| EP0995741A4 (en) * | 1997-06-27 | 2002-11-20 | Nippon Kayaku Kk | MEDICINES FOR THE TREATMENT / PREVENTION OF POLLAKIURIA OR INCONTINENCE AND TROPON DERIVATIVES |
| SE9904724D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| SE9904723D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission II |
| USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
| DE10161644A1 (de) * | 2001-12-14 | 2003-06-26 | Gruenenthal Gmbh | N,N'-disubstituierte Piperazin-Verbindungen |
| DE10161809A1 (de) * | 2001-12-14 | 2003-06-26 | Gruenenthal Gmbh | Arzneimittel enthaltend N,N'-disubstituierte Piperazin-Verbindungen |
| UY28538A1 (es) * | 2003-09-26 | 2005-04-29 | Vertex Pharma | Derivados de fenil-piperazina como moduladores de receptores muscarínicos |
| DK1773772T3 (da) | 2004-06-08 | 2010-09-13 | Nsab Af Neurosearch Sweden Ab | Nye disubstituerede phenylpiperidiner/piperaziner som modulatorer af dopaminneurotransmission |
| US7851629B2 (en) | 2004-06-08 | 2010-12-14 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission |
| MXPA06013941A (es) | 2004-06-08 | 2007-12-10 | Neurosearch Sweden Ab | Fenilpiperidinas disustituidas, novedosas, como moduladores de la neurotransmision de dopamina y serotonina. |
| ES2659577T3 (es) | 2004-10-13 | 2018-03-16 | Teva Pharmaceuticals International Gmbh | Proceso para la síntesis de 4-(3-metanosulfonilfenil)-1-N-propil-piperidina |
| SE529246C2 (sv) | 2005-10-13 | 2007-06-12 | Neurosearch Sweden Ab | Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission |
| TW201041868A (en) | 2009-03-20 | 2010-12-01 | Intervet Int Bv | Anthelmintic agents and their use |
| BRPI1003506B1 (pt) | 2010-09-24 | 2019-12-03 | Ache Int Bvi Ltd | composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a |
| WO2013086425A1 (en) | 2011-12-08 | 2013-06-13 | IVAX International GmbH | The hydrobromide salt of pridopidine |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3163649A (en) * | 1964-12-29 | Substituteb phenyl-piperazine | ||
| US3028390A (en) * | 1959-02-04 | 1962-04-03 | Parke Davis & Co | Substituted piperazine compounds and process for producing the same |
| FR1300728A (enExample) * | 1959-10-20 | 1962-07-02 | ||
| US3253989A (en) * | 1963-02-11 | 1966-05-31 | American Cyanamid Co | Process for producing anorexia |
| US3637705A (en) * | 1968-10-01 | 1972-01-25 | Abbott Lab | N-3 4-dihalo phenyl piperazines |
| US3770743A (en) * | 1971-03-08 | 1973-11-06 | Cutter Lab | 1-(1,3-dioxolan-4-yl-alkyl)-piperazines and piperazine alkane diols |
| FR2201084B1 (enExample) * | 1972-09-29 | 1975-10-31 | Bouchara Emile | |
| US3953449A (en) * | 1973-05-09 | 1976-04-27 | Synthelabo | 2-(4-M-CF3 or -SCF3 phenylpiperazino)-ethyl benzoates |
-
1977
- 1977-01-14 GB GB1539/77A patent/GB1560271A/en not_active Expired
- 1977-12-26 FR FR7739188A patent/FR2377392A1/fr active Granted
-
1978
- 1978-01-05 FI FI780034A patent/FI780034A7/fi not_active Application Discontinuation
- 1978-01-09 AU AU32290/78A patent/AU512266B2/en not_active Expired
- 1978-01-09 ZA ZA00780124A patent/ZA78124B/xx unknown
- 1978-01-10 NZ NZ186189A patent/NZ186189A/xx unknown
- 1978-01-11 DE DE19782800954 patent/DE2800954A1/de active Pending
- 1978-01-12 JP JP157778A patent/JPS5439085A/ja active Pending
- 1978-01-13 ES ES465939A patent/ES465939A1/es not_active Expired
- 1978-01-13 US US05/869,277 patent/US4203986A/en not_active Expired - Lifetime
- 1978-05-12 IT IT7823355A patent/IT7823355A0/it unknown
- 1978-05-12 BE BE187654A patent/BE867030A/xx unknown
- 1978-06-01 SE SE7806466A patent/SE7806466L/xx unknown
- 1978-07-12 LU LU79968A patent/LU79968A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| LU79968A1 (fr) | 1979-04-09 |
| FI780034A7 (fi) | 1978-07-15 |
| ZA78124B (en) | 1978-12-27 |
| FR2377392B1 (enExample) | 1980-08-22 |
| IT7823355A0 (it) | 1978-05-12 |
| BE867030A (fr) | 1978-11-13 |
| NZ186189A (en) | 1979-06-19 |
| SE7806466L (sv) | 1979-06-22 |
| AU3229078A (en) | 1979-07-19 |
| JPS5439085A (en) | 1979-03-24 |
| US4203986A (en) | 1980-05-20 |
| AU512266B2 (en) | 1980-10-02 |
| GB1560271A (en) | 1980-02-06 |
| FR2377392A1 (fr) | 1978-08-11 |
| DE2800954A1 (de) | 1978-07-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES465939A1 (es) | Procedimiento para preparar derivados de la meta-trifluome- tilfenil-perazina. | |
| ES477457A1 (es) | Procedimiento de preparacion de amidas de alcohilendiaminas. | |
| DE69202831D1 (de) | Depigmentiermittel Arbutosid enthaltend. | |
| FI934626A0 (fi) | Substituerade bensylaminokinuklidiner | |
| ES454779A1 (es) | Procedimiento para la obtencion de hidroxidiheterociclos eterados. | |
| ES8301962A1 (es) | Un procedimiento para la produccion de un derivado de carboslivilo. | |
| DK0835888T3 (da) | En ikke-tværbundet anionbytterharpiks og farmaceutisk sammensætning indeholdende denne | |
| ES461875A1 (es) | Procedimiento de preparacion de nuevos derivados del piperi-dil-indol. | |
| SE7501332L (enExample) | ||
| ES447010A1 (es) | Procedimiento para preparar 1-(3, 3, 3-triarifpropil-4-fe- nil)-4-piperidinamotanoles. | |
| ES437423A1 (es) | Procedimiento para la preparacion de nuevas piridobenzodia- zepinonas. | |
| DE3372095D1 (en) | Novel phenylpiperazine derivatives and process for producing the same | |
| ES481551A1 (es) | Procedimiento de preparacion de nuevos compuestos bis (ari- loxicarboxilicos). | |
| ES469234A1 (es) | Procedimiento de preparacion de derivados de piridazinona | |
| ES8400109A1 (es) | "un procedimiento para preparar esteres de acido 3-metilflavon-8-carboxilico". | |
| EP0150015A3 (en) | Norbornane and norbornene carboxylic acid amides, process for their preparation and their use as medicines | |
| ES422906A1 (es) | Un procedimiento para preparar nuevos derivados de 2-amino-indano. | |
| ES426040A1 (es) | Procedimiento de preparacion de esteres cicloalquil-alqui- licos de acidos que tienen el esqueleto del eburnano. | |
| ES472085A1 (es) | Un procedimiento para la preparacion de una composicion te- rapeutica para el tratamiento de enfermedades alergicas. | |
| ES476166A1 (es) | Procedimiento para la preparacion de nuevas imidazo-isoqui- nolein-dionas | |
| ES455202A1 (es) | Un procedimiento para la preparacion de una (vinilo 2, 2- disustituido)-y-butirolactona. | |
| ES459197A1 (es) | Procedimiento para preparar esteres oximicos de isonitroso- cianoacetamida. | |
| ES467791A1 (es) | Procedimiento para la obtencion de nuevos derivados del 1- fenil-2-amino-1,3-propandiol-n-alcohilo. | |
| ES8104247A1 (es) | Procedimiento para la preparacion de 3-alcoxi-6-alquiliden- hidracionopiridacina | |
| ES464150A1 (es) | Procedimiento para la preparacion de compuestos derivados defenil-amino-2-imidazolina |