ES463797A1 - Procedimiento para la preparacion de o-(2-hidroxipropil)- aldoximas sustituidas con radicales basicos - Google Patents
Procedimiento para la preparacion de o-(2-hidroxipropil)- aldoximas sustituidas con radicales basicosInfo
- Publication number
- ES463797A1 ES463797A1 ES463797A ES463797A ES463797A1 ES 463797 A1 ES463797 A1 ES 463797A1 ES 463797 A ES463797 A ES 463797A ES 463797 A ES463797 A ES 463797A ES 463797 A1 ES463797 A1 ES 463797A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- carbon atoms
- atom
- substituted
- nitrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 229910052757 nitrogen Inorganic materials 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 150000003254 radicals Chemical group 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- -1 hydroxyethyl group Chemical group 0.000 abstract 1
- 125000001434 methanylylidene group Chemical group [H]C#[*] 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/70—Nitro radicals
- C07D307/71—Nitro radicals attached in position 5
- C07D307/72—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2
- C07D307/73—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2 by amino or imino, or substituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/95—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by nitrogen atoms, attached to other ring members
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procedimiento para la preparación de O-(2-hidroxipropil)-aldoximas sustituidas con radicales básicos de la fórmula general (I) **(Fórmula)** en la que X significa un grupo metino e Y significa un átomo de oxígeno o X significa un átomo de nitrógeno e I significa el grupo NR3, representando R3 un átomo de hidrógeno, un grupo metilo, etilo o hidroxietilo, R1 y R2, independientemente entre sí, representan un átomo de hidrógeno, un grupo alcohilo o hidroxialcohilo en cada caso con hasta 6, preferentemente hasta 4, átomos de carbono.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762651084 DE2651084A1 (de) | 1976-11-09 | 1976-11-09 | Basisch substituirte o-(2-hydroxypropyl) -aldoxime, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES463797A1 true ES463797A1 (es) | 1979-09-01 |
Family
ID=5992723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES463797A Expired ES463797A1 (es) | 1976-11-09 | 1977-11-03 | Procedimiento para la preparacion de o-(2-hidroxipropil)- aldoximas sustituidas con radicales basicos |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4235899A (es) |
| JP (1) | JPS5359660A (es) |
| AT (1) | AT360517B (es) |
| BE (1) | BE860615A (es) |
| CA (1) | CA1117526A (es) |
| DE (1) | DE2651084A1 (es) |
| DK (1) | DK496777A (es) |
| ES (1) | ES463797A1 (es) |
| FR (1) | FR2370045A1 (es) |
| GB (1) | GB1540029A (es) |
| NL (1) | NL7712292A (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2651083A1 (de) * | 1976-11-09 | 1978-05-18 | Hoechst Ag | Neue o-alkylierte hydroxylamine, verfahren zu ihrer herstellung und ihre verwendung |
| CA1217491A (en) * | 1982-10-11 | 1987-02-03 | Erhardt Winkelmann | 3-aryl-7-chloro-3,4-dihydroacridine-1,9(2h,10h)-dione 1-oximes and 1-hydrazone derivatives, their salts, a process for their preparation, agents containing them and their use |
| DE3704604A1 (de) * | 1987-02-13 | 1988-08-25 | Mack Chem Pharm | Oximether von 2,6-dioxabicyclo(3.3.0)octanonen, herstellungsverfahren und anwendung als arzneimittel |
| US20160244435A1 (en) * | 2013-06-21 | 2016-08-25 | The Scripps Research Institute | Expanded therapeutic potential in nitroheteroaryl antimicrobials |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3184452A (en) * | 1965-05-18 | New aminoalkoxy compounds and process for theik manufacture | ||
| US3836528A (en) * | 1968-07-23 | 1974-09-17 | Dainippon Pharmaceutical Co | Alpha-(5-nitro-2-furyl)nitrones |
| US3583985A (en) * | 1969-04-09 | 1971-06-08 | Richardson Merrell Inc | Nitroimidazolyl nitrones |
| DE2311177A1 (de) * | 1973-03-07 | 1974-09-19 | Hoechst Ag | O-(dialkylaminoalkyl)-1-alkyl-5nitroimidazol-(2)-aldoxime und verfahren zu ihrer herstellung |
| DE2439629B2 (de) * | 1974-08-19 | 1977-06-02 | O-dialkylaminoalkyl-5-nitro-2- furanaldoxime, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1976
- 1976-11-09 DE DE19762651084 patent/DE2651084A1/de not_active Withdrawn
-
1977
- 1977-11-03 ES ES463797A patent/ES463797A1/es not_active Expired
- 1977-11-07 AT AT794377A patent/AT360517B/de not_active IP Right Cessation
- 1977-11-08 JP JP13316177A patent/JPS5359660A/ja active Pending
- 1977-11-08 BE BE182456A patent/BE860615A/xx unknown
- 1977-11-08 NL NL7712292A patent/NL7712292A/xx not_active Application Discontinuation
- 1977-11-08 CA CA000290445A patent/CA1117526A/en not_active Expired
- 1977-11-08 DK DK496777A patent/DK496777A/da not_active Application Discontinuation
- 1977-11-08 FR FR7733560A patent/FR2370045A1/fr not_active Withdrawn
- 1977-11-08 GB GB46474/77A patent/GB1540029A/en not_active Expired
- 1977-11-09 US US05/849,936 patent/US4235899A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR2370045A1 (fr) | 1978-06-02 |
| CA1117526A (en) | 1982-02-02 |
| NL7712292A (nl) | 1978-05-11 |
| GB1540029A (en) | 1979-02-07 |
| JPS5359660A (en) | 1978-05-29 |
| DK496777A (da) | 1978-05-10 |
| ATA794377A (de) | 1980-06-15 |
| DE2651084A1 (de) | 1978-12-14 |
| AT360517B (de) | 1981-01-12 |
| US4235899A (en) | 1980-11-25 |
| BE860615A (fr) | 1978-05-08 |
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