FR2370045A1 - O-(hydroxy-2 propyl) aldoximes substituees basiquement, leur procede de preparation et leur emploi comme medicaments - Google Patents

O-(hydroxy-2 propyl) aldoximes substituees basiquement, leur procede de preparation et leur emploi comme medicaments

Info

Publication number
FR2370045A1
FR2370045A1 FR7733560A FR7733560A FR2370045A1 FR 2370045 A1 FR2370045 A1 FR 2370045A1 FR 7733560 A FR7733560 A FR 7733560A FR 7733560 A FR7733560 A FR 7733560A FR 2370045 A1 FR2370045 A1 FR 2370045A1
Authority
FR
France
Prior art keywords
aldoximes
propyl
hydroxy
preparation
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7733560A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of FR2370045A1 publication Critical patent/FR2370045A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/70—Nitro radicals
    • C07D307/71—Nitro radicals attached in position 5
    • C07D307/72—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2
    • C07D307/73—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2 by amino or imino, or substituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/95—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by nitrogen atoms, attached to other ring members

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne des médicaments. On prépare des O-(hydroxy-2 propyl) aldoximes I substituées basiquement en faisant réagir un composé possédant un groupe structurel A avec un composé possédant le groupement Bn Dar insertion du maillon pontal C.
FR7733560A 1976-11-09 1977-11-08 O-(hydroxy-2 propyl) aldoximes substituees basiquement, leur procede de preparation et leur emploi comme medicaments Withdrawn FR2370045A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762651084 DE2651084A1 (de) 1976-11-09 1976-11-09 Basisch substituirte o-(2-hydroxypropyl) -aldoxime, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
FR2370045A1 true FR2370045A1 (fr) 1978-06-02

Family

ID=5992723

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7733560A Withdrawn FR2370045A1 (fr) 1976-11-09 1977-11-08 O-(hydroxy-2 propyl) aldoximes substituees basiquement, leur procede de preparation et leur emploi comme medicaments

Country Status (11)

Country Link
US (1) US4235899A (fr)
JP (1) JPS5359660A (fr)
AT (1) AT360517B (fr)
BE (1) BE860615A (fr)
CA (1) CA1117526A (fr)
DE (1) DE2651084A1 (fr)
DK (1) DK496777A (fr)
ES (1) ES463797A1 (fr)
FR (1) FR2370045A1 (fr)
GB (1) GB1540029A (fr)
NL (1) NL7712292A (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2651083A1 (de) * 1976-11-09 1978-05-18 Hoechst Ag Neue o-alkylierte hydroxylamine, verfahren zu ihrer herstellung und ihre verwendung
EP0106284B1 (fr) * 1982-10-11 1987-06-16 Hoechst Aktiengesellschaft 3-Aryl-7-chloro-3,4-dihydro-acridin-1,9-(2H,10H)-dione-1-oximes ou 1-hydrazones, leurs sels, leur procédé de préparation, les compositions pharmaceutiques les contenant, ainsi que leur application
DE3704604A1 (de) * 1987-02-13 1988-08-25 Mack Chem Pharm Oximether von 2,6-dioxabicyclo(3.3.0)octanonen, herstellungsverfahren und anwendung als arzneimittel
WO2014205414A1 (fr) * 2013-06-21 2014-12-24 The Regents Of The University Of California Potentiel thérapeutique étendu dans des antimicrobiens à nitrohétéroaryle

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2220267A1 (fr) * 1973-03-07 1974-10-04 Hoechst Ag
DE2439629A1 (de) * 1974-08-19 1976-03-04 Hoechst Ag O-dialkylaminoalkyl-5-nitro-2furanaldoxime und verfahren zu ihrer herstellung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3184452A (en) * 1965-05-18 New aminoalkoxy compounds and process for theik manufacture
US3836528A (en) * 1968-07-23 1974-09-17 Dainippon Pharmaceutical Co Alpha-(5-nitro-2-furyl)nitrones
US3583985A (en) * 1969-04-09 1971-06-08 Richardson Merrell Inc Nitroimidazolyl nitrones

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2220267A1 (fr) * 1973-03-07 1974-10-04 Hoechst Ag
DE2439629A1 (de) * 1974-08-19 1976-03-04 Hoechst Ag O-dialkylaminoalkyl-5-nitro-2furanaldoxime und verfahren zu ihrer herstellung
DE2516317A1 (de) * 1974-08-19 1977-04-14 Hoechst Ag O-diakylaminoalkyl-5-nitro-2-furanaldoxime und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
ATA794377A (de) 1980-06-15
GB1540029A (en) 1979-02-07
DK496777A (da) 1978-05-10
BE860615A (fr) 1978-05-08
CA1117526A (fr) 1982-02-02
ES463797A1 (es) 1979-09-01
JPS5359660A (en) 1978-05-29
US4235899A (en) 1980-11-25
AT360517B (de) 1981-01-12
DE2651084A1 (de) 1978-12-14
NL7712292A (nl) 1978-05-11

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Legal Events

Date Code Title Description
ST Notification of lapse