ES463768A1 - Process for the production of 9-d-arabinofuranosyl-adenine5-phosphate - Google Patents
Process for the production of 9-d-arabinofuranosyl-adenine5-phosphateInfo
- Publication number
- ES463768A1 ES463768A1 ES463768A ES463768A ES463768A1 ES 463768 A1 ES463768 A1 ES 463768A1 ES 463768 A ES463768 A ES 463768A ES 463768 A ES463768 A ES 463768A ES 463768 A1 ES463768 A1 ES 463768A1
- Authority
- ES
- Spain
- Prior art keywords
- arabinofuranosyl
- phosphate
- mixture
- aqueous
- adenine5
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The 9-( beta -D-arabinofuranosyl)adenine 5'-phosphate is prepared from a mixture obtained by reaction of 9-( beta -D-arabinofuranosyl)adenine with a phosphorylating agent, in a trialkyl phosphate as solvent. The mixture is then subjected to an aqueous hydrolysis, the pH of the hydrolysis mixture is adjusted to a value sufficiently high to bring about separation into aqueous and nonaqueous liquid phases the trialkyl phosphate, which is the solvent, is removed and then the product is precipitated so as to separate it from the residual aqueous mixture and it is isolated.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73842576A | 1976-11-03 | 1976-11-03 | |
| US05/831,703 US4123609A (en) | 1976-11-03 | 1977-09-12 | Process for the production of 9-(β-D-arabinofuranosyl)adenine, 5'-phosphate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES463768A1 true ES463768A1 (en) | 1978-06-01 |
Family
ID=27113366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES463768A Expired ES463768A1 (en) | 1976-11-03 | 1977-11-02 | Process for the production of 9-d-arabinofuranosyl-adenine5-phosphate |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS5356691A (en) |
| AT (1) | AT358187B (en) |
| CA (2) | CA1077030A (en) |
| CH (1) | CH626377A5 (en) |
| DE (1) | DE2749056A1 (en) |
| DK (1) | DK151263C (en) |
| ES (1) | ES463768A1 (en) |
| FR (1) | FR2370057A1 (en) |
| GB (1) | GB1559456A (en) |
| HK (1) | HK3884A (en) |
| NL (1) | NL191060C (en) |
| SE (1) | SE442404B (en) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1383572A (en) * | 1964-02-28 | 1964-12-24 | Necchi Spa | Improvements in automatic shut-off devices for sewing machines |
| DE1645896C3 (en) * | 1965-03-17 | 1975-01-02 | Ajinomoto Co., Inc., Tokio | Process for the preparation of 5'-ribonucleotides and S'-deoxyribonucleotides |
| BE756704A (en) * | 1969-09-26 | 1971-03-01 | Parke Davis & Co | PROCESS FOR THE PRODUCTION OF 5'-PHOSPHATE OF 9- (BETA-D- ARABINOFURANOSYL) ADENINE AND ITS SALTS |
-
1977
- 1977-11-02 FR FR7732871A patent/FR2370057A1/en active Granted
- 1977-11-02 CH CH1335777A patent/CH626377A5/en not_active IP Right Cessation
- 1977-11-02 DE DE19772749056 patent/DE2749056A1/en active Granted
- 1977-11-02 SE SE7712368A patent/SE442404B/en not_active IP Right Cessation
- 1977-11-02 NL NL7712102A patent/NL191060C/en not_active IP Right Cessation
- 1977-11-02 ES ES463768A patent/ES463768A1/en not_active Expired
- 1977-11-02 CA CA290,047A patent/CA1077030A/en not_active Expired
- 1977-11-02 GB GB4564777A patent/GB1559456A/en not_active Expired
- 1977-11-02 DK DK487177A patent/DK151263C/en not_active IP Right Cessation
- 1977-11-02 JP JP13216277A patent/JPS5356691A/en active Pending
- 1977-11-02 AT AT779577A patent/AT358187B/en not_active IP Right Cessation
-
1979
- 1979-12-18 CA CA342,182A patent/CA1088927A/en not_active Expired
-
1984
- 1984-01-12 HK HK3884A patent/HK3884A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK487177A (en) | 1978-05-04 |
| FR2370057A1 (en) | 1978-06-02 |
| FR2370057B1 (en) | 1980-06-13 |
| ATA779577A (en) | 1980-01-15 |
| DK151263C (en) | 1988-05-16 |
| NL191060B (en) | 1994-08-01 |
| CH626377A5 (en) | 1981-11-13 |
| CA1088927A (en) | 1980-11-04 |
| SE442404B (en) | 1985-12-23 |
| JPS5356691A (en) | 1978-05-23 |
| AT358187B (en) | 1980-08-25 |
| CA1077030A (en) | 1980-05-06 |
| NL191060C (en) | 1995-01-02 |
| GB1559456A (en) | 1980-01-16 |
| DK151263B (en) | 1987-11-16 |
| HK3884A (en) | 1984-01-20 |
| SE7712368L (en) | 1978-05-04 |
| DE2749056C2 (en) | 1987-07-16 |
| NL7712102A (en) | 1978-05-08 |
| DE2749056A1 (en) | 1978-05-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8106933A1 (en) | Process for the production of D-Glucosone and D-Fructose. | |
| HUP9900664A2 (en) | Process for preparing n-phosphonomethyliminodiacetic acid | |
| JPS52129788A (en) | Process for preparing porous cellulose beads | |
| ES8207187A1 (en) | A process for the separation of oil and/or phosphatidylethanolamine from alcohol soluble phosphatidylcholin products containing them. | |
| ES463768A1 (en) | Process for the production of 9-d-arabinofuranosyl-adenine5-phosphate | |
| CA2080790A1 (en) | Microbial Solubilization of Phosphate | |
| ZA776519B (en) | Process for the production of 9-(b-d-arabinofuranosyl)adenine,5'-phosphate | |
| GB1460182A (en) | Purification of aqueous phosphoric acid | |
| ES422744A1 (en) | Method for purifying phosphoric acid | |
| ES8504827A1 (en) | Process for the preparation of phosphoric diesters | |
| ES8100307A1 (en) | Process for the Preparation of L- alpha -Glycerylphosphoryl Choline | |
| ES8204429A1 (en) | Process for the preparation of L-aspartic acid N-thiocarboxyanhydride. | |
| GB1240285A (en) | Purification of phosphoric acid | |
| ES433752A1 (en) | Two stage process for producing ammonium phosphates | |
| GB1162062A (en) | Phosphoric Acid Purification | |
| GB1314220A (en) | Process for producing ammonium metatungstate | |
| ES8406376A1 (en) | Process for the purification of wet-process phosphoric acid. | |
| JPS5225088A (en) | Process for preparing a novel thermoresistant acetate kinase | |
| GB1491500A (en) | Method of making alkali metal phosphates from wet-process phosphoric acid | |
| GB1318224A (en) | Production of potassium dihydrogen phosphate | |
| JPS5437096A (en) | Method of procucing pure phosphoric acid | |
| GB1515170A (en) | Process for preparing alkali metal orthophosphates | |
| GB1436114A (en) | Purification of phosphoric acid crystallization process | |
| ES330972A2 (en) | Procedure for the obtaining of phosphoric acid alkylamides. (Machine-translation by Google Translate, not legally binding) | |
| JPS537629A (en) | Improved method for isolating and purifying vinylphenol |