ES8100307A1 - Process for the Preparation of L- alpha -Glycerylphosphoryl Choline - Google Patents

Process for the Preparation of L- alpha -Glycerylphosphoryl Choline

Info

Publication number
ES8100307A1
ES8100307A1 ES487473A ES487473A ES8100307A1 ES 8100307 A1 ES8100307 A1 ES 8100307A1 ES 487473 A ES487473 A ES 487473A ES 487473 A ES487473 A ES 487473A ES 8100307 A1 ES8100307 A1 ES 8100307A1
Authority
ES
Spain
Prior art keywords
alpha
preparation
alcoholysis
glycerylphosphoryl choline
lecithin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES487473A
Other languages
Spanish (es)
Other versions
ES487473A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LPB INSTITUTO FARMACEUTICO SpA
Lpb Istituto Farmaceutico SpA
Original Assignee
LPB INSTITUTO FARMACEUTICO SpA
Lpb Istituto Farmaceutico SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LPB INSTITUTO FARMACEUTICO SpA, Lpb Istituto Farmaceutico SpA filed Critical LPB INSTITUTO FARMACEUTICO SpA
Publication of ES487473A0 publication Critical patent/ES487473A0/en
Publication of ES8100307A1 publication Critical patent/ES8100307A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

L- alpha -glycerylphosphoryl choline is obtained from lecithin in a pure state by subjecting purified lecithin to alcoholysis in the presence of a catalytic amount of an alkali metal alkoxide. The process can be carried out economically on a commercial scale because of the ease of recovery of the desired reaction product. A methanol/sodium methoxide system is preferably used in the alcoholysis.
ES487473A 1979-09-17 1980-01-04 Process for the Preparation of L- alpha -Glycerylphosphoryl Choline Expired ES8100307A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT25761/79A IT1123187B (en) 1979-09-17 1979-09-17 PROCESS FOR THE PREPARATION OF L-ALPHA-GLYCERYLPHOSPHORYLCHOLINE

Publications (2)

Publication Number Publication Date
ES487473A0 ES487473A0 (en) 1980-11-01
ES8100307A1 true ES8100307A1 (en) 1980-11-01

Family

ID=11217655

Family Applications (1)

Application Number Title Priority Date Filing Date
ES487473A Expired ES8100307A1 (en) 1979-09-17 1980-01-04 Process for the Preparation of L- alpha -Glycerylphosphoryl Choline

Country Status (9)

Country Link
JP (1) JPS5643290A (en)
AR (1) AR225159A1 (en)
CH (1) CH642083A5 (en)
DE (1) DE3000246C2 (en)
ES (1) ES8100307A1 (en)
FR (1) FR2464961A1 (en)
GB (1) GB2058792A (en)
IT (1) IT1123187B (en)
MX (1) MX6294E (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT383130B (en) * 1984-05-15 1987-05-25 Chemie Linz Ag METHOD FOR THE PRODUCTION OF PHOSPHATIDYLCHOLINES AND PHOSPHATIDYLETHANOLAMINES SUBSTITUTED DIFFERENTLY AT C1 AND C2 OVER THE NEW COMPOUNDS 1-0-TRITYLGLYCEROPHOSPHOCHOLIN OR RELATED (1-0, N-DITYHOHOLINE)
IT1201477B (en) * 1985-10-04 1989-02-02 Istituto Chemioterapico PROCEDURE FOR THE PREPARATION OF L-ALPHA-GLYCERYLPHOSPHORYLCHOLINE, L-ALPHA-GLYCERYLPHOSPHORYLETHANOLOMINE AND L-ALPHA-GLYCERYLPHOSPHORYLINOSITOL FROM RAW AND / OR DEOLEATE LECITHINS
JPH066744B2 (en) * 1986-05-15 1994-01-26 住友金属工業株式会社 Method for manufacturing high Ni-Fe alloy hot rolled steel sheet
JP2572757B2 (en) * 1986-11-27 1997-01-16 川崎製鉄株式会社 Billet processing method and billet processing apparatus in hot rolling equipment
FR2614621B1 (en) * 1987-04-29 1989-08-11 Ire Celltarg Sa PROCESS FOR THE PURIFICATION OF PHOSPHATIDYLCHOLINES AND PRODUCTS OBTAINED
CN103193821A (en) * 2013-03-29 2013-07-10 山东罗欣药业股份有限公司 Synthesis method of L-alpha-glyceryl phosphoryl choline
CN109134532A (en) * 2018-07-19 2019-01-04 芜湖福民生物药业股份有限公司 The method that glycerolphosphocholine is prepared using powdered soybean phospholipid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2864848A (en) * 1954-07-19 1958-12-16 Ca Nat Research Council Method of producing l-alpha-glycerylphosphorylcholine

Also Published As

Publication number Publication date
FR2464961B1 (en) 1985-05-17
ES487473A0 (en) 1980-11-01
MX6294E (en) 1985-03-18
FR2464961A1 (en) 1981-03-20
JPS6341920B2 (en) 1988-08-19
JPS5643290A (en) 1981-04-21
DE3000246A1 (en) 1981-04-02
CH642083A5 (en) 1984-03-30
IT1123187B (en) 1986-04-30
DE3000246C2 (en) 1989-02-02
GB2058792A (en) 1981-04-15
AR225159A1 (en) 1982-02-26
IT7925761A0 (en) 1979-09-17

Similar Documents

Publication Publication Date Title
ES8106933A1 (en) Process for the production of D-Glucosone and D-Fructose.
ES471832A1 (en) Method for the continuous preparation of alcoholates
ES8500285A1 (en) Process for preparation of alkyl glycosides.
EP0388857A3 (en) Process for production of alkyl glycoside excellent in hue
ES8100307A1 (en) Process for the Preparation of L- alpha -Glycerylphosphoryl Choline
EP0152965A3 (en) Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxy-menthyl)-purines and certain derivatives
ES8207494A1 (en) Process for the production of glyceryl ethers
BE879801A (en) PROCESS FOR PRODUCING ETHERS BY REACTION OF OLEFINS WITH ALCOHOLS
GB2003144B (en) Process for producing a hydrofuran and a 1,4-diol
ES8405352A1 (en) Continuous alkoxidation process.
EP0185553A3 (en) Process for preparation of poly(tetramethylene ether) glycol
ES8400727A1 (en) Process for making allylic esters of tetrabromophthalic acid.
ES476111A1 (en) Process for preparing aliphatic diperoxydicarboxylic acids.
GB1487842A (en) Prostenoic acids and process for their manufacture
JPS53147026A (en) Continuous preparation of thioglycolic acid
GB1501327A (en) Manufacture of glycol ethers using an anhydrous catalyst
EP0299720A3 (en) Process for the condensation of alcohols
AU536552B2 (en) Process for generation of haloalkyl alkyl ethers useful to produce n-substituted-2-haloacetanilides
ES8204429A1 (en) Process for the preparation of L-aspartic acid N-thiocarboxyanhydride.
JPS54148740A (en) Production of 3-methyl-2-cyclopentene-1-one
ES469645A1 (en) Process of preparing 3-bromophthalide
DE3263545D1 (en) Process for the preparation of 4-alkoxy-acetoacetic-acid esters
EG15987A (en) Process and intermediates for preparation of 1,1-dioxopenicillan-oyloxymethyl 6-beta-aminopenicillanate
JPS5373529A (en) Preparation of hydroquinone
JPS5519241A (en) Preparation of 4-homotwistane

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010201