ES463632A1 - Procedimiento de preparacion de derivados de la piperidina. - Google Patents

Procedimiento de preparacion de derivados de la piperidina.

Info

Publication number
ES463632A1
ES463632A1 ES463632A ES463632A ES463632A1 ES 463632 A1 ES463632 A1 ES 463632A1 ES 463632 A ES463632 A ES 463632A ES 463632 A ES463632 A ES 463632A ES 463632 A1 ES463632 A1 ES 463632A1
Authority
ES
Spain
Prior art keywords
piperidine derivatives
relates
salts
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES463632A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anphar SA
Original Assignee
Anphar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anphar SA filed Critical Anphar SA
Publication of ES463632A1 publication Critical patent/ES463632A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES463632A 1976-10-29 1977-10-28 Procedimiento de preparacion de derivados de la piperidina. Expired ES463632A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB45146/76A GB1586468A (en) 1976-10-29 1976-10-29 Piperidine derivatives

Publications (1)

Publication Number Publication Date
ES463632A1 true ES463632A1 (es) 1978-07-16

Family

ID=10436065

Family Applications (2)

Application Number Title Priority Date Filing Date
ES463632A Expired ES463632A1 (es) 1976-10-29 1977-10-28 Procedimiento de preparacion de derivados de la piperidina.
ES463633A Expired ES463633A1 (es) 1976-10-29 1977-10-28 Procedimiento de preparacion de derivados de la piperidina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES463633A Expired ES463633A1 (es) 1976-10-29 1977-10-28 Procedimiento de preparacion de derivados de la piperidina.

Country Status (7)

Country Link
US (1) US4367232A (enExample)
JP (1) JPS5377069A (enExample)
CA (1) CA1095044A (enExample)
DE (1) DE2747960A1 (enExample)
ES (2) ES463632A1 (enExample)
FR (1) FR2369263A1 (enExample)
GB (1) GB1586468A (enExample)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962115A (en) * 1981-10-01 1990-10-09 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives
US5137896A (en) * 1981-10-01 1992-08-11 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)benzamide derivatives
US5057525A (en) * 1981-10-01 1991-10-15 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl) benzamide derivatives
FR2534255B1 (fr) * 1982-10-11 1985-07-12 Delalande Sa Nouveaux derives de la 4-aroylamino piperidine, leur procede de preparation et leur application en therapeutique
FR2546169B1 (fr) * 1983-05-20 1986-03-21 Delalande Sa N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique
GB8527052D0 (en) * 1985-11-02 1985-12-04 Beecham Group Plc Compounds
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
GB9016581D0 (en) * 1990-07-27 1990-09-12 Ici Plc Fungicides
GB9016580D0 (en) * 1990-07-27 1990-09-12 Ici Plc Fungicides
TR27569A (tr) * 1992-01-24 1995-06-13 Ici Plc Yeni fungisidal asilaminobenzamidler, bunlarin hazirlanis islemleri ve bitkilerdeki mantar enfeksiyonlariyla mücadelede kullanimlari.
US5739135A (en) * 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5827875A (en) * 1996-05-10 1998-10-27 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5885983A (en) * 1996-05-10 1999-03-23 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5883109A (en) * 1996-07-24 1999-03-16 Bristol-Myers Squibb Company Method for lowering serum lipid levels employing an MTP inhibitor in combination with another cholesterol lowering drug
SE9902987D0 (sv) * 1999-08-24 1999-08-24 Astra Pharma Prod Novel compounds
IL151164A0 (en) * 2000-03-06 2003-04-10 Acadia Pharm Inc Azacyclic compounds for use in the treatment of serotonin related diseases
CA2406652A1 (en) * 2000-04-20 2001-11-01 Nps Allelix Corp. Aminopiperidines for use as glyt-1 inhibitors
GB0011838D0 (en) * 2000-05-17 2000-07-05 Astrazeneca Ab Chemical compounds
RU2286801C2 (ru) * 2001-05-01 2006-11-10 Институт Нефтехимического Синтеза Имени А.В. Топчиева Российской Академии Наук Двухфазные биоадгезионные композиции, абсорбирующие воду
KR20100008799A (ko) * 2001-12-28 2010-01-26 아카디아 파마슈티칼스 인코포레이티드 모노아민 수용체 조정자로서의 스피로아자사이클릭 화합물
US7538222B2 (en) * 2002-06-24 2009-05-26 Acadia Pharmaceuticals, Inc. N-substituted piperidine derivatives as serotonin receptor agents
US7253186B2 (en) * 2002-06-24 2007-08-07 Carl-Magnus Andersson N-substituted piperidine derivatives as serotonin receptor agents
BR0312217A (pt) * 2002-06-24 2005-05-10 Acadia Pharm Inc Compostos, métodos de inibição da atividade/ativação de um receptor monoaminérgico e método de tratamento de condição doentia associada a um receptor de monoaminergético
MY139563A (en) * 2002-09-04 2009-10-30 Bristol Myers Squibb Co Heterocyclic aromatic compounds useful as growth hormone secretagogues
CN101780080B (zh) 2003-01-16 2014-06-04 阿卡蒂亚药品公司 用于神经退行性疾病的治疗的选择性五羟色胺2a/2c受体反向激动剂
KR100697944B1 (ko) * 2003-02-10 2007-03-20 니폰 쇼쿠바이 컴파니 리미티드 수분-흡수제
SE0301369D0 (sv) * 2003-05-09 2003-05-09 Astrazeneca Ab Chemical compounds
US7820695B2 (en) * 2004-05-21 2010-10-26 Acadia Pharmaceuticals, Inc. Selective serotonin receptor inverse agonists as therapeutics for disease
US20050261278A1 (en) * 2004-05-21 2005-11-24 Weiner David M Selective serotonin receptor inverse agonists as therapeutics for disease
US7790899B2 (en) * 2004-09-27 2010-09-07 Acadia Pharmaceuticals, Inc. Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms
ES2530258T3 (es) * 2004-09-27 2015-02-27 Acadia Pharmaceuticals Inc. Síntesis de una forma cristalina de sal tartrato de N-(4-fluorobencil)-N-(1-metilpiperidin-4-il)-N'-(4-(2-metilpropiloxi)fenilmetil)carbamida
JP2008524276A (ja) * 2004-12-20 2008-07-10 エフ．ホフマン−ラ ロシュ アーゲー ４−アミノピペリジン誘導体
WO2008116024A2 (en) 2007-03-19 2008-09-25 Acadia Pharmaceuticals Inc. Combinations of 5-ht2a inverse agonists and antagonists with antipsychotics
CA2700331A1 (en) * 2007-09-21 2009-03-26 Acadia Pharmaceuticals, Inc. Co-administration of pimavanserin with other agents
DK3325444T3 (da) 2015-07-20 2021-10-04 Acadia Pharm Inc Fremgangsmåder til fremstilling af n-(4-fluorbenzyl)-n-(1-methylpiperidin-4-yl)-n'-(4-(2-methylpropyloxy)phenylmethyl)carbamid og dets tartratsalt og polymorf form c
US10953000B2 (en) 2016-03-25 2021-03-23 Acadia Pharmaceuticals Inc. Combination of pimavanserin and cytochrome P450 modulators
WO2017165635A1 (en) 2016-03-25 2017-09-28 Acadia Pharmaceuticals Inc. Combination of pimavanserin and cytochrome p450 modulators
EP3558311A1 (en) 2016-12-20 2019-10-30 Acadia Pharmaceuticals Inc. Pimavanserin alone or in combination for use in the treatment of alzheimer's disease psychosis
EP3615028A1 (en) 2017-04-28 2020-03-04 Acadia Pharmaceuticals Inc. Pimavanserin for treating impulse control disorder
EP3675827A1 (en) 2017-08-30 2020-07-08 Acadia Pharmaceuticals Inc. Formulations of pimavanserin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2745837A (en) * 1954-01-21 1956-05-15 Schering Corp Benzhydryl ethers of alkyl piperidinols
NL270803A (enExample) * 1960-11-09
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
US3963745A (en) * 1972-04-03 1976-06-15 A. H. Robins Company, Incorporated Method for controlling emesis with N-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides
US3862139A (en) * 1972-06-23 1975-01-21 Delmar Chem Heterocyclic benzamide compounds
CA1046066A (en) * 1973-08-23 1979-01-09 Tomio Muro 1-(methylated piperidino (and pyrrolidin -1-yl)-3-(substituted phenoxy)-2-propanols
DE2513136C3 (de) 1974-03-21 1981-04-30 Anphar S.A., Madrid N-(1-Benzylpiperid-4-yl)-benzamide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
JPS5377069A (en) 1978-07-08
FR2369263B1 (enExample) 1980-06-13
DE2747960A1 (de) 1978-05-11
US4367232A (en) 1983-01-04
CA1095044A (en) 1981-02-03
ES463633A1 (es) 1978-07-01
GB1586468A (en) 1981-03-18
FR2369263A1 (fr) 1978-05-26

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