ES463072A1 - Procedimiento para la obtencion de n'-(2'furanidil)-5-flu- oro-uracilo. - Google Patents
Procedimiento para la obtencion de n'-(2'furanidil)-5-flu- oro-uracilo.Info
- Publication number
- ES463072A1 ES463072A1 ES463072A ES463072A ES463072A1 ES 463072 A1 ES463072 A1 ES 463072A1 ES 463072 A ES463072 A ES 463072A ES 463072 A ES463072 A ES 463072A ES 463072 A1 ES463072 A1 ES 463072A1
- Authority
- ES
- Spain
- Prior art keywords
- uracil
- fluoro
- furanidyl
- preparation
- new process
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 4
- WFWLQNSHRPWKFK-UHFFFAOYSA-N Tegafur Chemical compound O=C1NC(=O)C(F)=CN1C1OCCC1 WFWLQNSHRPWKFK-UHFFFAOYSA-N 0.000 title abstract 2
- ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 2
- JKTCBAGSMQIFNL-UHFFFAOYSA-N 2,3-dihydrofuran Chemical compound C1CC=CO1 JKTCBAGSMQIFNL-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 230000001093 anti-cancer Effects 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960002949 fluorouracil Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- WFWLQNSHRPWKFK-ZCFIWIBFSA-N tegafur Chemical compound O=C1NC(=O)C(F)=CN1[C@@H]1OCCC1 WFWLQNSHRPWKFK-ZCFIWIBFSA-N 0.000 abstract 1
- 229960001674 tegafur Drugs 0.000 abstract 1
- 229940035893 uracil Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL50671A IL50671A (en) | 1976-10-12 | 1976-10-12 | Process for the preparation of n1-(2'furanidyl)-5-fluoro-uracil and bis-2'-furanidylether as intermediate therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES463072A1 true ES463072A1 (es) | 1978-11-16 |
Family
ID=11049169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES463072A Expired ES463072A1 (es) | 1976-10-12 | 1977-10-05 | Procedimiento para la obtencion de n'-(2'furanidil)-5-flu- oro-uracilo. |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US4174446A (de) |
| JP (2) | JPS5346987A (de) |
| AT (1) | AT363101B (de) |
| AU (1) | AU508758B2 (de) |
| BE (1) | BE859529A (de) |
| CH (1) | CH637127A5 (de) |
| DE (1) | DE2744956A1 (de) |
| DK (1) | DK143230C (de) |
| ES (1) | ES463072A1 (de) |
| FI (1) | FI63570C (de) |
| FR (1) | FR2367762A1 (de) |
| GB (1) | GB1554393A (de) |
| IL (1) | IL50671A (de) |
| NL (1) | NL7711171A (de) |
| NO (1) | NO146911C (de) |
| NZ (1) | NZ185348A (de) |
| RO (1) | RO72832A (de) |
| SE (1) | SE7711381L (de) |
| YU (1) | YU243177A (de) |
| ZA (1) | ZA776011B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6135521Y2 (de) * | 1981-01-16 | 1986-10-16 | ||
| JPS57199883A (en) * | 1981-06-03 | 1982-12-07 | Teijin Ltd | Deep color process of fabric |
| JP2009102076A (ja) * | 2009-01-05 | 2009-05-14 | Masayuki Makita | ボトルキャップ |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3912734A (en) * | 1972-11-20 | 1975-10-14 | Solomon Aronovich Giller | Method for preparing N{HD 1{B -(2{40 -furanidyl)-and N{HD 1{B -2(2{40 -pyranidyl) uracils |
-
1976
- 1976-10-12 IL IL50671A patent/IL50671A/xx unknown
-
1977
- 1977-10-05 JP JP12044677A patent/JPS5346987A/ja active Pending
- 1977-10-05 FI FI772933A patent/FI63570C/fi not_active IP Right Cessation
- 1977-10-05 ES ES463072A patent/ES463072A1/es not_active Expired
- 1977-10-05 NZ NZ185348A patent/NZ185348A/xx unknown
- 1977-10-05 JP JP12044777A patent/JPS5346960A/ja active Pending
- 1977-10-06 DE DE19772744956 patent/DE2744956A1/de not_active Withdrawn
- 1977-10-06 GB GB41580/77A patent/GB1554393A/en not_active Expired
- 1977-10-07 ZA ZA00776011A patent/ZA776011B/xx unknown
- 1977-10-10 YU YU02431/77A patent/YU243177A/xx unknown
- 1977-10-10 BE BE181577A patent/BE859529A/xx not_active IP Right Cessation
- 1977-10-10 SE SE7711381A patent/SE7711381L/xx not_active Application Discontinuation
- 1977-10-10 DK DK449477A patent/DK143230C/da not_active IP Right Cessation
- 1977-10-11 US US05/841,023 patent/US4174446A/en not_active Expired - Lifetime
- 1977-10-11 NO NO773463A patent/NO146911C/no unknown
- 1977-10-11 RO RO7791810A patent/RO72832A/ro unknown
- 1977-10-11 NL NL7711171A patent/NL7711171A/xx not_active Application Discontinuation
- 1977-10-11 CH CH1239577A patent/CH637127A5/de not_active IP Right Cessation
- 1977-10-11 AT AT0725277A patent/AT363101B/de not_active IP Right Cessation
- 1977-10-12 AU AU29618/77A patent/AU508758B2/en not_active Expired
- 1977-10-12 FR FR7730685A patent/FR2367762A1/fr active Granted
-
1979
- 1979-04-30 US US06/034,422 patent/US4212814A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NZ185348A (en) | 1980-04-28 |
| NO146911C (no) | 1982-12-29 |
| DK449477A (da) | 1978-04-13 |
| US4174446A (en) | 1979-11-13 |
| FI772933A (fi) | 1978-04-13 |
| JPS5346987A (en) | 1978-04-27 |
| IL50671A (en) | 1980-03-31 |
| YU243177A (en) | 1983-01-21 |
| SE7711381L (sv) | 1978-04-13 |
| FI63570C (fi) | 1983-07-11 |
| ATA725277A (de) | 1980-12-15 |
| FI63570B (fi) | 1983-03-31 |
| RO72832A (ro) | 1982-09-09 |
| CH637127A5 (de) | 1983-07-15 |
| IL50671A0 (en) | 1976-12-31 |
| US4212814A (en) | 1980-07-15 |
| JPS5346960A (en) | 1978-04-27 |
| FR2367762A1 (fr) | 1978-05-12 |
| DK143230B (da) | 1981-07-27 |
| NL7711171A (nl) | 1978-04-14 |
| NO773463L (no) | 1978-04-13 |
| FR2367762B1 (de) | 1982-03-05 |
| AT363101B (de) | 1981-07-10 |
| ZA776011B (en) | 1978-11-29 |
| DK143230C (da) | 1981-11-30 |
| AU508758B2 (en) | 1980-04-03 |
| DE2744956A1 (de) | 1978-04-13 |
| BE859529A (fr) | 1978-04-10 |
| AU2961877A (en) | 1979-04-26 |
| GB1554393A (en) | 1979-10-17 |
| NO146911B (no) | 1982-09-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE7901126L (sv) | Prostacyklinanaloger | |
| ATE26695T1 (de) | Katalytische herstellung von dimethylaether. | |
| FI88795B (fi) | Foerfarande foer framstaellning av tienyletylaminer | |
| ES463072A1 (es) | Procedimiento para la obtencion de n'-(2'furanidil)-5-flu- oro-uracilo. | |
| JPS5612357A (en) | Production of polymethylenepolyphenylpolycarbamate | |
| ES8604135A1 (es) | Un procedimiento para la preparacion de nuevos 16-fluor-16, 17-dideshidro prostanoides | |
| US4082776A (en) | 6-Alkoxy-4α-hydroxy-2β-tetrahydropyranacetic acid γ-lactones | |
| ES483249A1 (es) | Procedimiento para la obtencion de diciclopentilen(2,2'-bis (4-alquil-6-t-butilfenoles). | |
| KR840001162A (ko) | 항괘양 작용이 우수한 신규 화합물의 제조방법 | |
| JPS52103392A (en) | Fluorination catalyst for haloganated hydrocarbon | |
| JPS51146482A (en) | Process for preparing n1-(2- tetrahydrofuryl)-5-fluorouracil | |
| SE7710757L (sv) | Buren vanadinkatalysator samt forfarande for framstellning av nitriler | |
| ES461758A1 (es) | Nuevo procedimiento de obtencion de derivados tiocromanicos. | |
| JPS57177348A (en) | Oxidizing catalyst and preparation thereof | |
| JPS51125363A (en) | Process for freparation of alkylidenebiscyclohexylamines | |
| US4461917A (en) | 9-Deoxy-9-methylene-PGE compounds | |
| JPS53135926A (en) | Synthesis of 1,3,6-tricyanohexane | |
| JPS57192380A (en) | Preparation of 4-alkoxy-1,3-dioxane-5-carbonitriles | |
| JPS5522610A (en) | Preparation of carboxylic acid ester | |
| JPS53137913A (en) | Preparation of cis-epoxysuccinic acid or cis-epoxysuccinate salt | |
| KR860002473A (ko) | 4-메틸-5-티오포름아미디노메틸이미다졸 디하이드로클로라이드의 제조방법 | |
| ES2004876A6 (es) | Un nuevo procedimiento para la preparacion de 4-(6' -metoxi-2' -naftil)butan-2-ona". | |
| JPS537632A (en) | Diphenylamine derivatives | |
| KR840002347A (ko) | N-(2,6-디클로로페닐)아세트아미딘의 제조방법 | |
| JPS5430129A (en) | Preparation of toluic acid amide |