ES463072A1 - Procedimiento para la obtencion de n'-(2'furanidil)-5-flu- oro-uracilo. - Google Patents

Procedimiento para la obtencion de n'-(2'furanidil)-5-flu- oro-uracilo.

Info

Publication number
ES463072A1
ES463072A1 ES463072A ES463072A ES463072A1 ES 463072 A1 ES463072 A1 ES 463072A1 ES 463072 A ES463072 A ES 463072A ES 463072 A ES463072 A ES 463072A ES 463072 A1 ES463072 A1 ES 463072A1
Authority
ES
Spain
Prior art keywords
uracil
fluoro
furanidyl
preparation
new process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES463072A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abic Ltd
Original Assignee
Abic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abic Ltd filed Critical Abic Ltd
Publication of ES463072A1 publication Critical patent/ES463072A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)

Abstract

Procedimiento para la obtención de N1-(2'-furanidil)-5-fluoro-uracilo, caracterizado por comprender la reacción de 2,3-dihidrofurano con agua y en presencia de una cantidad catalítica de un catalizador acídico a un pH por debajo de 2,5 eliminar el exceso de los materiales de partida que no han reaccionado y hacer reaccionar la mezcla obtenida con 5-fluoro-uracilo sililatado, en presencia de uracilo catalítio del tipo Friedel Crafts en un disolvente orgánico inerte.
ES463072A 1976-10-12 1977-10-05 Procedimiento para la obtencion de n'-(2'furanidil)-5-flu- oro-uracilo. Expired ES463072A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL50671A IL50671A (en) 1976-10-12 1976-10-12 Process for the preparation of n1-(2'furanidyl)-5-fluoro-uracil and bis-2'-furanidylether as intermediate therefor

Publications (1)

Publication Number Publication Date
ES463072A1 true ES463072A1 (es) 1978-11-16

Family

ID=11049169

Family Applications (1)

Application Number Title Priority Date Filing Date
ES463072A Expired ES463072A1 (es) 1976-10-12 1977-10-05 Procedimiento para la obtencion de n'-(2'furanidil)-5-flu- oro-uracilo.

Country Status (20)

Country Link
US (2) US4174446A (es)
JP (2) JPS5346987A (es)
AT (1) AT363101B (es)
AU (1) AU508758B2 (es)
BE (1) BE859529A (es)
CH (1) CH637127A5 (es)
DE (1) DE2744956A1 (es)
DK (1) DK143230C (es)
ES (1) ES463072A1 (es)
FI (1) FI63570C (es)
FR (1) FR2367762A1 (es)
GB (1) GB1554393A (es)
IL (1) IL50671A (es)
NL (1) NL7711171A (es)
NO (1) NO146911C (es)
NZ (1) NZ185348A (es)
RO (1) RO72832A (es)
SE (1) SE7711381L (es)
YU (1) YU243177A (es)
ZA (1) ZA776011B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6135521Y2 (es) * 1981-01-16 1986-10-16
JPS57199883A (en) * 1981-06-03 1982-12-07 Teijin Ltd Deep color process of fabric
JP2009102076A (ja) * 2009-01-05 2009-05-14 Masayuki Makita ボトルキャップ

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3912734A (en) * 1972-11-20 1975-10-14 Solomon Aronovich Giller Method for preparing N{HD 1{B -(2{40 -furanidyl)-and N{HD 1{B -2(2{40 -pyranidyl) uracils

Also Published As

Publication number Publication date
DE2744956A1 (de) 1978-04-13
JPS5346960A (en) 1978-04-27
CH637127A5 (de) 1983-07-15
FI63570C (fi) 1983-07-11
RO72832A (ro) 1982-09-09
FI63570B (fi) 1983-03-31
DK143230C (da) 1981-11-30
FR2367762B1 (es) 1982-03-05
IL50671A0 (en) 1976-12-31
US4212814A (en) 1980-07-15
SE7711381L (sv) 1978-04-13
FR2367762A1 (fr) 1978-05-12
US4174446A (en) 1979-11-13
GB1554393A (en) 1979-10-17
NZ185348A (en) 1980-04-28
ZA776011B (en) 1978-11-29
YU243177A (en) 1983-01-21
ATA725277A (de) 1980-12-15
AU508758B2 (en) 1980-04-03
NL7711171A (nl) 1978-04-14
NO773463L (no) 1978-04-13
DK143230B (da) 1981-07-27
IL50671A (en) 1980-03-31
JPS5346987A (en) 1978-04-27
DK449477A (da) 1978-04-13
AT363101B (de) 1981-07-10
NO146911B (no) 1982-09-20
BE859529A (fr) 1978-04-10
AU2961877A (en) 1979-04-26
FI772933A (fi) 1978-04-13
NO146911C (no) 1982-12-29

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