ES462882A1 - Procedimiento para la obtencion de compuestos esteroides oxigenados en la posicion 19. - Google Patents

Procedimiento para la obtencion de compuestos esteroides oxigenados en la posicion 19.

Info

Publication number
ES462882A1
ES462882A1 ES462882A ES462882A ES462882A1 ES 462882 A1 ES462882 A1 ES 462882A1 ES 462882 A ES462882 A ES 462882A ES 462882 A ES462882 A ES 462882A ES 462882 A1 ES462882 A1 ES 462882A1
Authority
ES
Spain
Prior art keywords
group
steroid compounds
oxygen function
novel steroid
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES462882A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LU75936A external-priority patent/LU75936A1/xx
Priority claimed from LU76966A external-priority patent/LU76966A1/xx
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES462882A1 publication Critical patent/ES462882A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/007—3 membered carbocyclic rings in position 6-7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001—Lactones
    • C07J21/003—Lactones at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C07J33/007—Cyclic thioketals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Abstract

Procedimiento para la obtención de compuestos esteroides oxigenados en la posición 19, de la serie espiroxano, de fórmula: **(Fórmula 01)** Donde R1 significa un átomo de hidrógeno y R2 significa un átomo de hidrógeno o un grupo alcanoiltio inferior, o R1 y R2 juntos significan un enlace carbono-carbono o un grupo metileno alfa- o beta-orientado, R3 significa un resto de la fórmula parcial: **(Fórmula 02)** Donde Ra3 y Rb3 cada uno individualmente significa un átomo de hidrógeno o un resto alquilo inferior y Rc3 significa un grupo hidroxilo libre o esterificado o un grupo alcoxi inferior, o Ra3 y Rb3 juntos significan un grupo oxo, en cuyo caso Rc3 significa un átomo de hidrógeno, un resto alquilo, un grupo hidroxilo libre o un grupo alcoxi inferior, y R4 significa dos átomos de hidrógeno o un grupo oxo.
ES462882A 1976-10-05 1977-10-04 Procedimiento para la obtencion de compuestos esteroides oxigenados en la posicion 19. Expired ES462882A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU75936A LU75936A1 (es) 1976-10-05 1976-10-05
LU76966A LU76966A1 (es) 1977-03-17 1977-03-17

Publications (1)

Publication Number Publication Date
ES462882A1 true ES462882A1 (es) 1978-12-16

Family

ID=26640214

Family Applications (1)

Application Number Title Priority Date Filing Date
ES462882A Expired ES462882A1 (es) 1976-10-05 1977-10-04 Procedimiento para la obtencion de compuestos esteroides oxigenados en la posicion 19.

Country Status (16)

Country Link
US (1) US4150127A (es)
JP (1) JPS5346952A (es)
AT (1) ATA705277A (es)
AU (1) AU512101B2 (es)
CA (1) CA1099701A (es)
DD (1) DD132349A5 (es)
DE (1) DE2744255A1 (es)
DK (1) DK142707B (es)
ES (1) ES462882A1 (es)
FI (1) FI58779C (es)
FR (1) FR2367079A1 (es)
IL (1) IL53058A0 (es)
NL (1) NL7710939A (es)
NO (1) NO773381L (es)
NZ (1) NZ185341A (es)
SE (1) SE7711094L (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4259240A (en) * 1979-09-28 1981-03-31 Advance Biofactures Corporation Synthesis of furyl intermediates, and cardenolides and their isomers prepared therefrom
DE3326013A1 (de) * 1983-07-15 1985-01-24 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-methylen-17(alpha)-pregna-4,6-dien-21-carbonsaeuresalze, diese enthaltende pharmazeutische praeparate sowie verfahren zu deren herstellung
DE3330084A1 (de) * 1983-08-17 1985-03-07 Schering AG, 1000 Berlin und 4709 Bergkamen 7(alpha)-alkoxycarbonyl-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone und deren 21-carbonsaeuresalze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
JPH0425327Y2 (es) * 1985-11-08 1992-06-17
FR2656309B1 (fr) * 1989-12-22 1992-05-07 Roussel Uclaf Nouveaux produits sterouides comportant en position 10, un radical ethyle substitue, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant.
WO1995018821A2 (en) * 1994-01-06 1995-07-13 Sri International Novel antiandrogenic agents and related pharmaceutical compositions and methods of use
WO2012107513A1 (en) * 2011-02-10 2012-08-16 Crystal Pharma, S.A.U. Process for obtaining drospirenone
CH708607A2 (fr) 2013-09-26 2015-03-31 Montres Breguet Sa Pièce d'horlogerie musicale ou à sonnerie.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4058522A (en) * 1973-07-09 1977-11-15 Richter Gedeon Vegyeszeti Gyar Rt. Steroids effective against heavy-metal poisoning
US4028348A (en) * 1976-02-17 1977-06-07 Richter Gedeon Vegyeszeti Gyar Rt 6-Amino-5β,19-cycloandrostane derivatives

Also Published As

Publication number Publication date
CA1099701A (en) 1981-04-21
DK142707C (es) 1981-10-05
FI58779B (fi) 1980-12-31
AU2932577A (en) 1979-04-12
FR2367079B1 (es) 1980-04-18
FI58779C (fi) 1981-04-10
JPS5346952A (en) 1978-04-27
DD132349A5 (de) 1978-09-20
SE7711094L (sv) 1978-04-06
FI772900A (fi) 1978-04-06
DK438577A (es) 1978-04-06
DE2744255A1 (de) 1978-04-06
ATA705277A (de) 1981-07-15
US4150127A (en) 1979-04-17
AU512101B2 (en) 1980-09-25
DK142707B (da) 1980-12-29
IL53058A0 (en) 1977-12-30
NZ185341A (en) 1979-06-19
NO773381L (no) 1978-04-06
FR2367079A1 (fr) 1978-05-05
NL7710939A (nl) 1978-04-07

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