ES462517A1 - Procedimiento para la produccion de una forma polimorfica decimeticina a cristalograficamente pura de modo sustancial. - Google Patents

Procedimiento para la produccion de una forma polimorfica decimeticina a cristalograficamente pura de modo sustancial.

Info

Publication number
ES462517A1
ES462517A1 ES462517A ES462517A ES462517A1 ES 462517 A1 ES462517 A1 ES 462517A1 ES 462517 A ES462517 A ES 462517A ES 462517 A ES462517 A ES 462517A ES 462517 A1 ES462517 A1 ES 462517A1
Authority
ES
Spain
Prior art keywords
cimetidine
ridge
suspension
heterocyclic compound
strong
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES462517A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10407431&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES462517(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB3906576A external-priority patent/GB1543238A/en
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Publication of ES462517A1 publication Critical patent/ES462517A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Procedimiento para la producción de una forma polimórfica de cimetidina A cristalograficamente pura de modo sustancial, que tiene un espectro infra-rojo (discos de 1% KBr) que muestra crestas amplias muy fuertes en1400 y 1385 cm-1, una cresta aguda fuerte en 1205 cm-1 y una cresta agua-media en 1155 cm-1 y ninguna cresta en 1180 cm-1, caracterizado porque comprende disolver cimetidina en un disolvente no acuoso, caliente, tal como acetonitrilo, acetona, metilisobutilcetena, tolueno o un alcanol inferior; enfriar la solución resultante con agitación suficiente para asegurar una eficaz transferencia térmica para producir una suspensión de cimetidina A en el disolvente, cuya suspensión presenta unas buenas propiedades de manipulación; y separar la cimetidina A.
ES462517A 1976-09-21 1977-09-21 Procedimiento para la produccion de una forma polimorfica decimeticina a cristalograficamente pura de modo sustancial. Expired ES462517A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3906576A GB1543238A (en) 1976-09-21 1976-09-21 Polymorph of cimetidine

Publications (1)

Publication Number Publication Date
ES462517A1 true ES462517A1 (es) 1978-07-01

Family

ID=10407431

Family Applications (1)

Application Number Title Priority Date Filing Date
ES462517A Expired ES462517A1 (es) 1976-09-21 1977-09-21 Procedimiento para la produccion de una forma polimorfica decimeticina a cristalograficamente pura de modo sustancial.

Country Status (18)

Country Link
JP (1) JPS60185767A (es)
AR (1) AR218267A1 (es)
BG (1) BG28050A3 (es)
CS (1) CS207482B1 (es)
DD (1) DD129906A5 (es)
DK (1) DK417677A (es)
ES (1) ES462517A1 (es)
FI (1) FI772542A (es)
GR (1) GR61173B (es)
IT (1) IT1086352B (es)
MY (1) MY8400026A (es)
NL (1) NL7710354A (es)
NO (1) NO773225L (es)
PL (1) PL103681B1 (es)
PT (1) PT66927B (es)
SE (1) SE7710518L (es)
ZA (1) ZA774857B (es)
ZM (1) ZM7077A1 (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
GB1397436A (en) * 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
GB1531221A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for preparing guanidine derivatives

Also Published As

Publication number Publication date
JPS60185767A (ja) 1985-09-21
DD129906A5 (de) 1978-02-15
DK417677A (da) 1978-03-22
ZM7077A1 (en) 1978-08-21
PL103681B1 (pl) 1979-07-31
IT1086352B (it) 1985-05-28
ZA774857B (en) 1978-06-28
CS207482B1 (en) 1981-07-31
SE7710518L (sv) 1978-03-22
MY8400026A (en) 1984-12-31
FI772542A (es) 1977-08-29
PL200960A1 (pl) 1978-05-22
NO773225L (no) 1978-03-22
PT66927A (en) 1977-09-01
JPS6234759B2 (es) 1987-07-28
BG28050A3 (en) 1980-02-25
PT66927B (en) 1979-03-13
NL7710354A (nl) 1978-03-23
GR61173B (en) 1978-10-03
AR218267A1 (es) 1980-05-30

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