ES462080A1 - Ergot alkaloid peptide derivatives - Google Patents
Ergot alkaloid peptide derivativesInfo
- Publication number
- ES462080A1 ES462080A1 ES462080A ES462080A ES462080A1 ES 462080 A1 ES462080 A1 ES 462080A1 ES 462080 A ES462080 A ES 462080A ES 462080 A ES462080 A ES 462080A ES 462080 A1 ES462080 A1 ES 462080A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- peptide derivatives
- alkyl
- ergot alkaloid
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/02—Ergot alkaloids of the cyclic peptide type
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Process for obtaining derivatives of ergot peptide alkaloids of formula I, *** (See formula) where R1 is alkyl of 1 to 4 carbon atoms, R2 is hydrogen, alkyl of 1 to 4 carbon atoms or benzyl, R3 and R5, independently, are hydrogen or methyl, R4 is hydrogen or C 1-4 -alkyl, and R6 and R7, together, form a single bond, or each of R6 and R7 is hydrogen, or R6 is methoxy and R7 is hydrogen. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1128676A CH623591A5 (en) | 1976-09-06 | 1976-09-06 | Process for the preparation of ergopeptide alkaloid derivatives |
| CH1128776A CH623592A5 (en) | 1976-09-06 | 1976-09-06 | Process for the preparation of ergopeptide alkaloid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES462080A1 true ES462080A1 (en) | 1978-12-01 |
Family
ID=25708069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES462080A Expired ES462080A1 (en) | 1976-09-06 | 1977-06-02 | Ergot alkaloid peptide derivatives |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS5331698A (en) |
| AU (1) | AU512027B2 (en) |
| CA (1) | CA1105007A (en) |
| DE (1) | DE2738730A1 (en) |
| DK (1) | DK147390C (en) |
| ES (1) | ES462080A1 (en) |
| FI (1) | FI64942C (en) |
| FR (1) | FR2363571A1 (en) |
| GB (2) | GB1590150A (en) |
| IE (1) | IE46152B1 (en) |
| IL (1) | IL52896A (en) |
| NL (1) | NL7709683A (en) |
| NZ (1) | NZ185098A (en) |
| PT (1) | PT67003B (en) |
| SE (1) | SE435839B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8604035B2 (en) * | 2011-06-23 | 2013-12-10 | Map Pharmaceuticals, Inc. | Fluoroergoline analogs |
-
1977
- 1977-06-02 ES ES462080A patent/ES462080A1/en not_active Expired
- 1977-08-27 DE DE19772738730 patent/DE2738730A1/en not_active Withdrawn
- 1977-08-29 SE SE7709645A patent/SE435839B/en unknown
- 1977-08-29 DK DK382777A patent/DK147390C/en active
- 1977-08-29 FI FI772557A patent/FI64942C/en not_active IP Right Cessation
- 1977-08-31 GB GB9862/80A patent/GB1590150A/en not_active Expired
- 1977-08-31 GB GB36338/77A patent/GB1590149A/en not_active Expired
- 1977-09-02 NL NL7709683A patent/NL7709683A/en not_active Application Discontinuation
- 1977-09-02 CA CA286,056A patent/CA1105007A/en not_active Expired
- 1977-09-05 NZ NZ185098A patent/NZ185098A/en unknown
- 1977-09-05 IL IL52896A patent/IL52896A/en unknown
- 1977-09-05 PT PT67003A patent/PT67003B/en unknown
- 1977-09-05 FR FR7726893A patent/FR2363571A1/en active Granted
- 1977-09-05 IE IE1838/77A patent/IE46152B1/en unknown
- 1977-09-05 JP JP10596277A patent/JPS5331698A/en active Pending
- 1977-09-06 AU AU28572/77A patent/AU512027B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL52896A0 (en) | 1977-11-30 |
| DK147390C (en) | 1985-02-04 |
| FR2363571A1 (en) | 1978-03-31 |
| JPS5331698A (en) | 1978-03-25 |
| GB1590149A (en) | 1981-05-28 |
| GB1590150A (en) | 1981-05-28 |
| NL7709683A (en) | 1978-03-08 |
| CA1105007A (en) | 1981-07-14 |
| PT67003B (en) | 1979-05-14 |
| AU2857277A (en) | 1979-03-15 |
| IE46152L (en) | 1978-03-06 |
| DK147390B (en) | 1984-07-16 |
| FI772557A (en) | 1978-03-07 |
| SE7709645L (en) | 1978-03-07 |
| AU512027B2 (en) | 1980-09-18 |
| DK382777A (en) | 1978-03-07 |
| IL52896A (en) | 1980-07-31 |
| IE46152B1 (en) | 1983-03-09 |
| FI64942C (en) | 1984-02-10 |
| FI64942B (en) | 1983-10-31 |
| DE2738730A1 (en) | 1978-03-16 |
| PT67003A (en) | 1977-10-01 |
| NZ185098A (en) | 1980-04-28 |
| FR2363571B1 (en) | 1980-04-18 |
| SE435839B (en) | 1984-10-22 |
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