FR2363571A1 - NEW DERIVATIVES OF PEPTIDIC ALKALOIDS OF RYE ERGOT - Google Patents

NEW DERIVATIVES OF PEPTIDIC ALKALOIDS OF RYE ERGOT

Info

Publication number
FR2363571A1
FR2363571A1 FR7726893A FR7726893A FR2363571A1 FR 2363571 A1 FR2363571 A1 FR 2363571A1 FR 7726893 A FR7726893 A FR 7726893A FR 7726893 A FR7726893 A FR 7726893A FR 2363571 A1 FR2363571 A1 FR 2363571A1
Authority
FR
France
Prior art keywords
peptidic
alkaloids
new derivatives
rye ergot
ergot
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7726893A
Other languages
French (fr)
Other versions
FR2363571B1 (en
Inventor
Peter Stutz
Paul Stadler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1128676A external-priority patent/CH623591A5/en
Priority claimed from CH1128776A external-priority patent/CH623592A5/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2363571A1 publication Critical patent/FR2363571A1/en
Application granted granted Critical
Publication of FR2363571B1 publication Critical patent/FR2363571B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02Ergot alkaloids of the cyclic peptide type

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne de nouveaux dérivés d'alcaloïdes peptidiques de l'ergot de seigle et leur préparation. Les composés de l'invention répondent à la formule :The present invention relates to novel peptide alkaloid derivatives of rye ergot and their preparation. The compounds of the invention correspond to the formula:

FR7726893A 1976-09-06 1977-09-05 NEW DERIVATIVES OF PEPTIDIC ALKALOIDS OF RYE ERGOT Granted FR2363571A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1128676A CH623591A5 (en) 1976-09-06 1976-09-06 Process for the preparation of ergopeptide alkaloid derivatives
CH1128776A CH623592A5 (en) 1976-09-06 1976-09-06 Process for the preparation of ergopeptide alkaloid derivatives

Publications (2)

Publication Number Publication Date
FR2363571A1 true FR2363571A1 (en) 1978-03-31
FR2363571B1 FR2363571B1 (en) 1980-04-18

Family

ID=25708069

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7726893A Granted FR2363571A1 (en) 1976-09-06 1977-09-05 NEW DERIVATIVES OF PEPTIDIC ALKALOIDS OF RYE ERGOT

Country Status (15)

Country Link
JP (1) JPS5331698A (en)
AU (1) AU512027B2 (en)
CA (1) CA1105007A (en)
DE (1) DE2738730A1 (en)
DK (1) DK147390C (en)
ES (1) ES462080A1 (en)
FI (1) FI64942C (en)
FR (1) FR2363571A1 (en)
GB (2) GB1590149A (en)
IE (1) IE46152B1 (en)
IL (1) IL52896A (en)
NL (1) NL7709683A (en)
NZ (1) NZ185098A (en)
PT (1) PT67003B (en)
SE (1) SE435839B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103827113A (en) * 2011-06-23 2014-05-28 Map药物公司 Novel fluoroergoline analogs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NV786/77 *

Also Published As

Publication number Publication date
CA1105007A (en) 1981-07-14
JPS5331698A (en) 1978-03-25
FI64942C (en) 1984-02-10
ES462080A1 (en) 1978-12-01
PT67003A (en) 1977-10-01
SE435839B (en) 1984-10-22
DK147390C (en) 1985-02-04
SE7709645L (en) 1978-03-07
DK382777A (en) 1978-03-07
AU2857277A (en) 1979-03-15
FR2363571B1 (en) 1980-04-18
PT67003B (en) 1979-05-14
FI64942B (en) 1983-10-31
IE46152B1 (en) 1983-03-09
DE2738730A1 (en) 1978-03-16
AU512027B2 (en) 1980-09-18
FI772557A (en) 1978-03-07
DK147390B (en) 1984-07-16
IE46152L (en) 1978-03-06
IL52896A0 (en) 1977-11-30
GB1590149A (en) 1981-05-28
NL7709683A (en) 1978-03-08
IL52896A (en) 1980-07-31
NZ185098A (en) 1980-04-28
GB1590150A (en) 1981-05-28

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Legal Events

Date Code Title Description
ST Notification of lapse