ES460694A1 - Procedure for the obtaining of 2-piperidine alkyl- (1-benzofurans or 1,4-benzodioxanes). (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the obtaining of 2-piperidine alkyl- (1-benzofurans or 1,4-benzodioxanes). (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES460694A1 ES460694A1 ES460694A ES460694A ES460694A1 ES 460694 A1 ES460694 A1 ES 460694A1 ES 460694 A ES460694 A ES 460694A ES 460694 A ES460694 A ES 460694A ES 460694 A1 ES460694 A1 ES 460694A1
- Authority
- ES
- Spain
- Prior art keywords
- hph
- signifies
- acid addition
- lower alkyl
- integer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for obtaining 2-piperidi-noalkyl- (1-benzofurans or 1,4-benzodioxanes) of general formula I **(See formula)** where Ph means a 1,2-phenylene residue, which is optionally substituted by 1 to 3 same or different substituents, selected from lower alkyl, hydroxy, mercapto, lower alkoxy, lower alkylenedioxy, benzyloxy, lower alkylthio, halogen, trifluoromethyl, nitro or amino, x means oxygen or sulfur, m is the integer 0 or 1 and n is 1 to 4, each of the symbols p and q represent an integer from 1 to 3, where (p + q) is the number 4, each of the symbols R1 and R2 means hydrogen, lower alkyl or HPh, R3 means hydrogen, hydroxy, lower alkoxy, lower or higher alkanoyloxy, R4 means lower alkyl, HPh-lower alkyl, HPh or naphthyl, which may be substituted as Ph, furyl, thienyl, pyridyl, benzofuryl, benzothienyl, quinolyl or isoquinolyl, the heterocyclic moieties of which are optionally substituted as Ph, as well as the acid addition salts, especially the therapeutically usable acid addition salts is one of these compounds, characterized in that a compound of general formula III **(See formula)** where A signifies a group of formula (see formula) or (see formula), where Y'signifies an esterified hydroxy group, capable of reaction, R5 signifies hydrogen or R1 and R2 together form another bond C, C, R'4 signifies R4 or HPh-lower alkanoyl each of the symbols r and s means the integer 0 or 2, where (r + s) is the number 2 or 4, if desired, a free compound obtained is reduced to an addition salt. of acid or an acid addition salt obtained in the free compound or in another acid addition salt, and/or, if desired, a mixture of isomers or racemates obtained is separated into the different isomers or racemates, and/or, if desired, the racemates obtained are dissociated in the optical antipodes. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/589,118 US4039676A (en) | 1975-06-23 | 1975-06-23 | 2-piperidinoalkyl-1,4-benzodioxans |
Publications (1)
Publication Number | Publication Date |
---|---|
ES460694A1 true ES460694A1 (en) | 1978-05-16 |
Family
ID=24356671
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES449069A Expired ES449069A1 (en) | 1975-06-23 | 1976-06-21 | Procedure for the obtaining of 2-piperidinoalquil- (1- benzofuranos or 1,4-benzodioxanos). (Machine-translation by Google Translate, not legally binding) |
ES460696A Expired ES460696A1 (en) | 1975-06-23 | 1977-07-13 | Procedure for the obtaining of 2-piperidine alkyl- (1-benzofuranos-o-1,4-benzodioxanos). (Machine-translation by Google Translate, not legally binding) |
ES460695A Expired ES460695A1 (en) | 1975-06-23 | 1977-07-13 | Procedure for the obtaining of 2-piperidine alkyl- (1-benzofurans or v, 4-benzodioxanes). (Machine-translation by Google Translate, not legally binding) |
ES460694A Expired ES460694A1 (en) | 1975-06-23 | 1977-07-13 | Procedure for the obtaining of 2-piperidine alkyl- (1-benzofurans or 1,4-benzodioxanes). (Machine-translation by Google Translate, not legally binding) |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES449069A Expired ES449069A1 (en) | 1975-06-23 | 1976-06-21 | Procedure for the obtaining of 2-piperidinoalquil- (1- benzofuranos or 1,4-benzodioxanos). (Machine-translation by Google Translate, not legally binding) |
ES460696A Expired ES460696A1 (en) | 1975-06-23 | 1977-07-13 | Procedure for the obtaining of 2-piperidine alkyl- (1-benzofuranos-o-1,4-benzodioxanos). (Machine-translation by Google Translate, not legally binding) |
ES460695A Expired ES460695A1 (en) | 1975-06-23 | 1977-07-13 | Procedure for the obtaining of 2-piperidine alkyl- (1-benzofurans or v, 4-benzodioxanes). (Machine-translation by Google Translate, not legally binding) |
Country Status (13)
Country | Link |
---|---|
CS (1) | CS198190B2 (en) |
DD (1) | DD126408A5 (en) |
DK (1) | DK278976A (en) |
ES (4) | ES449069A1 (en) |
FI (1) | FI761818A (en) |
GR (1) | GR60557B (en) |
HU (1) | HU174277B (en) |
IE (1) | IE43244B1 (en) |
IL (1) | IL49863A0 (en) |
NO (1) | NO762158L (en) |
NZ (1) | NZ181241A (en) |
PT (1) | PT65229B (en) |
ZA (2) | ZA762264B (en) |
-
1976
- 1976-04-14 ZA ZA762264A patent/ZA762264B/en unknown
- 1976-06-16 PT PT6522976A patent/PT65229B/en unknown
- 1976-06-21 GR GR51055A patent/GR60557B/en unknown
- 1976-06-21 ES ES449069A patent/ES449069A1/en not_active Expired
- 1976-06-22 IE IE134376A patent/IE43244B1/en unknown
- 1976-06-22 ZA ZA00763705A patent/ZA763705B/en unknown
- 1976-06-22 CS CS411376A patent/CS198190B2/en unknown
- 1976-06-22 DK DK278976A patent/DK278976A/en unknown
- 1976-06-22 HU HU76CI1670A patent/HU174277B/en unknown
- 1976-06-22 NO NO762158A patent/NO762158L/no unknown
- 1976-06-22 IL IL49863A patent/IL49863A0/en unknown
- 1976-06-22 FI FI761818A patent/FI761818A/fi not_active Application Discontinuation
- 1976-06-22 NZ NZ18124176A patent/NZ181241A/en unknown
- 1976-06-22 DD DD19350376A patent/DD126408A5/xx unknown
-
1977
- 1977-07-13 ES ES460696A patent/ES460696A1/en not_active Expired
- 1977-07-13 ES ES460695A patent/ES460695A1/en not_active Expired
- 1977-07-13 ES ES460694A patent/ES460694A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
PT65229A (en) | 1976-07-01 |
ES449069A1 (en) | 1977-11-16 |
ZA762264B (en) | 1977-04-27 |
FI761818A (en) | 1976-12-24 |
GR60557B (en) | 1978-06-22 |
ES460696A1 (en) | 1978-07-01 |
IE43244L (en) | 1976-12-23 |
CS198190B2 (en) | 1980-05-30 |
NZ181241A (en) | 1978-04-03 |
PT65229B (en) | 1977-11-23 |
IE43244B1 (en) | 1981-01-14 |
IL49863A0 (en) | 1976-08-31 |
ZA763705B (en) | 1978-02-22 |
HU174277B (en) | 1979-12-28 |
NO762158L (en) | 1976-12-27 |
DD126408A5 (en) | 1977-07-13 |
ES460695A1 (en) | 1978-05-01 |
DK278976A (en) | 1976-12-24 |
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