ES8302706A1 - Phenylquinolizidine - Google Patents

Phenylquinolizidine

Info

Publication number
ES8302706A1
ES8302706A1 ES512072A ES512072A ES8302706A1 ES 8302706 A1 ES8302706 A1 ES 8302706A1 ES 512072 A ES512072 A ES 512072A ES 512072 A ES512072 A ES 512072A ES 8302706 A1 ES8302706 A1 ES 8302706A1
Authority
ES
Spain
Prior art keywords
formula
rent
reaction
lower rent
racematos
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES512072A
Other languages
Spanish (es)
Other versions
ES512072A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES8302706A1 publication Critical patent/ES8302706A1/en
Publication of ES512072A0 publication Critical patent/ES512072A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Procedure for the obtaining of phenylquinolicidins, in the form of racemato or of the binders and of their acid addition salts, of formula (I), in which x, y, r and r can be several radical; r es oxygen or sulfur; and r is lower rent. It consists of the reaction of the rent of a compound of formula (II), in which all symbols have the same meaning as in formula (I). The reaction is effected with an N-alkilling agent such as a lower rent halide. The racematos obtained can be resolved in the optical antipodas. These compounds have pharmacological applications for their neuroletic, antimimetic and/or analgesic activities. (Machine-translation by Google Translate, not legally binding)
ES512072A 1980-04-11 1982-05-11 "A PROCEDURE FOR THE PREPARATION OF PHENYL-QUINOLICIDINS". Granted ES512072A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH278480 1980-04-11

Publications (2)

Publication Number Publication Date
ES8302706A1 true ES8302706A1 (en) 1983-02-01
ES512072A0 ES512072A0 (en) 1983-02-01

Family

ID=4241517

Family Applications (4)

Application Number Title Priority Date Filing Date
ES512071A Granted ES512071A0 (en) 1980-04-11 1982-05-11 "A PROCEDURE FOR THE PREPARATION OF PHENYL-QUINOLICIDINS".
ES512074A Expired ES8302704A1 (en) 1980-04-11 1982-05-11 Phenylquinolizidine
ES512072A Granted ES512072A0 (en) 1980-04-11 1982-05-11 "A PROCEDURE FOR THE PREPARATION OF PHENYL-QUINOLICIDINS".
ES512073A Granted ES512073A0 (en) 1980-04-11 1982-05-11 "A PROCEDURE FOR THE PREPARATION OF PHENYL-QUINOLICIDINE

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES512071A Granted ES512071A0 (en) 1980-04-11 1982-05-11 "A PROCEDURE FOR THE PREPARATION OF PHENYL-QUINOLICIDINS".
ES512074A Expired ES8302704A1 (en) 1980-04-11 1982-05-11 Phenylquinolizidine

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES512073A Granted ES512073A0 (en) 1980-04-11 1982-05-11 "A PROCEDURE FOR THE PREPARATION OF PHENYL-QUINOLICIDINE

Country Status (7)

Country Link
JP (1) JPS56158783A (en)
KR (1) KR830005219A (en)
BR (1) BR8102218A (en)
CS (1) CS222700B2 (en)
ES (4) ES512071A0 (en)
GR (1) GR74868B (en)
ZA (1) ZA812285B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019134985A1 (en) * 2018-01-08 2019-07-11 F. Hoffmann-La Roche Ag Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors

Also Published As

Publication number Publication date
JPS56158783A (en) 1981-12-07
KR830005219A (en) 1983-08-03
ES8302703A1 (en) 1983-02-01
ES8302707A1 (en) 1983-02-01
GR74868B (en) 1984-07-12
ES512074A0 (en) 1983-02-01
ES8302704A1 (en) 1983-02-01
CS222700B2 (en) 1983-07-29
ES512073A0 (en) 1983-02-01
ES512071A0 (en) 1983-02-01
BR8102218A (en) 1981-10-13
ES512072A0 (en) 1983-02-01
ZA812285B (en) 1982-04-28

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