ES8302704A1 - Phenylquinolizidine - Google Patents

Phenylquinolizidine

Info

Publication number
ES8302704A1
ES8302704A1 ES512074A ES512074A ES8302704A1 ES 8302704 A1 ES8302704 A1 ES 8302704A1 ES 512074 A ES512074 A ES 512074A ES 512074 A ES512074 A ES 512074A ES 8302704 A1 ES8302704 A1 ES 8302704A1
Authority
ES
Spain
Prior art keywords
formula
racematos
neuroletic
fenilquinolicidinas
antipodas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES512074A
Other languages
Spanish (es)
Other versions
ES512074A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES8302704A1 publication Critical patent/ES8302704A1/en
Publication of ES512074A0 publication Critical patent/ES512074A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Procedure for obtaining fenilquinolicidinas, racemate or enantiomer and their salts addition acid of formula (I), wherein x, y, r and r can be various types of radical. It comprises reacting a compound oxo, of formula (II) wherein x, y, r, r and r have the same meaning as in the formula (I), phosphorus pentachloride. The reaction is carried out following conventional methods. The racematos obtained can be resolved in the optical antipodas. These compounds have pharmacological applications for their neuroletic, antimimetic and/or analgesic activities. (Machine-translation by Google Translate, not legally binding)
ES512074A 1980-04-11 1982-05-11 "A PROCEDURE FOR THE PREPARATION OF PHENYL-QUINOLICIDINE Granted ES512074A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH278480 1980-04-11

Publications (2)

Publication Number Publication Date
ES8302704A1 true ES8302704A1 (en) 1983-02-01
ES512074A0 ES512074A0 (en) 1983-02-01

Family

ID=4241517

Family Applications (4)

Application Number Title Priority Date Filing Date
ES512071A Expired ES8302703A1 (en) 1980-04-11 1982-05-11 Phenylquinolizidine
ES512073A Expired ES8302707A1 (en) 1980-04-11 1982-05-11 Phenylquinolizidine
ES512074A Granted ES512074A0 (en) 1980-04-11 1982-05-11 "A PROCEDURE FOR THE PREPARATION OF PHENYL-QUINOLICIDINE
ES512072A Expired ES8302706A1 (en) 1980-04-11 1982-05-11 Phenylquinolizidine

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES512071A Expired ES8302703A1 (en) 1980-04-11 1982-05-11 Phenylquinolizidine
ES512073A Expired ES8302707A1 (en) 1980-04-11 1982-05-11 Phenylquinolizidine

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES512072A Expired ES8302706A1 (en) 1980-04-11 1982-05-11 Phenylquinolizidine

Country Status (7)

Country Link
JP (1) JPS56158783A (en)
KR (1) KR830005219A (en)
BR (1) BR8102218A (en)
CS (1) CS222700B2 (en)
ES (4) ES8302703A1 (en)
GR (1) GR74868B (en)
ZA (1) ZA812285B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019134985A1 (en) * 2018-01-08 2019-07-11 F. Hoffmann-La Roche Ag Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors

Also Published As

Publication number Publication date
ES512072A0 (en) 1983-02-01
GR74868B (en) 1984-07-12
ES8302706A1 (en) 1983-02-01
BR8102218A (en) 1981-10-13
CS222700B2 (en) 1983-07-29
ES512073A0 (en) 1983-02-01
KR830005219A (en) 1983-08-03
JPS56158783A (en) 1981-12-07
ES512071A0 (en) 1983-02-01
ES8302703A1 (en) 1983-02-01
ES8302707A1 (en) 1983-02-01
ZA812285B (en) 1982-04-28
ES512074A0 (en) 1983-02-01

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