ES2004876A6 - Manufacture of compound - Google Patents

Manufacture of compound

Info

Publication number
ES2004876A6
ES2004876A6 ES8700370A ES8700370A ES2004876A6 ES 2004876 A6 ES2004876 A6 ES 2004876A6 ES 8700370 A ES8700370 A ES 8700370A ES 8700370 A ES8700370 A ES 8700370A ES 2004876 A6 ES2004876 A6 ES 2004876A6
Authority
ES
Spain
Prior art keywords
compound
formula
manufacture
inflammatory
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8700370A
Other languages
Spanish (es)
Inventor
Erol Ali Faruk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES2004876A6 publication Critical patent/ES2004876A6/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Said process is characterized in that it comprises submitting a catalytic hydrogenation a compound of formula (II) or a salt thereof, wherein q is a group protector, to produce the compound of formula (I). The compound of formula (I) is applicable as an anti-inflammatory. (Machine-translation by Google Translate, not legally binding)
ES8700370A 1986-02-15 1987-02-13 Manufacture of compound Expired ES2004876A6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868603766A GB8603766D0 (en) 1986-02-15 1986-02-15 Process

Publications (1)

Publication Number Publication Date
ES2004876A6 true ES2004876A6 (en) 1989-02-16

Family

ID=10593122

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8700370A Expired ES2004876A6 (en) 1986-02-15 1987-02-13 Manufacture of compound

Country Status (8)

Country Link
JP (1) JPS62215545A (en)
CH (1) CH670631A5 (en)
DK (1) DK74987A (en)
ES (1) ES2004876A6 (en)
GB (1) GB8603766D0 (en)
GR (1) GR870253B (en)
NL (1) NL8700353A (en)
SE (1) SE8700589L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1285567B1 (en) * 1996-02-21 1998-06-18 Alfa Chem Ital NEW PROCESS FOR THE SYNTHESIS OF NABUMETONE
US5756851A (en) * 1996-10-21 1998-05-26 Albemarle Corporation Production of nabumetone or precursors thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2014993B (en) * 1977-11-03 1982-05-12 Beecham Group Ltd Chemical compounds
US4221741A (en) * 1978-01-27 1980-09-09 Beecham Group Limited Preparation of 4(6'-methoxy-2'-naphthyl)butan-2-one

Also Published As

Publication number Publication date
SE8700589L (en) 1987-08-16
JPS62215545A (en) 1987-09-22
DK74987A (en) 1987-08-16
DK74987D0 (en) 1987-02-13
NL8700353A (en) 1987-09-01
GR870253B (en) 1987-06-16
GB8603766D0 (en) 1986-03-19
CH670631A5 (en) 1989-06-30
SE8700589D0 (en) 1987-02-13

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991108