ES2004522A6 - Novel manufacture of compound - Google Patents

Novel manufacture of compound

Info

Publication number
ES2004522A6
ES2004522A6 ES8700373A ES8700373A ES2004522A6 ES 2004522 A6 ES2004522 A6 ES 2004522A6 ES 8700373 A ES8700373 A ES 8700373A ES 8700373 A ES8700373 A ES 8700373A ES 2004522 A6 ES2004522 A6 ES 2004522A6
Authority
ES
Spain
Prior art keywords
compound
hydrogenation
carboxi
novel manufacture
naftil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8700373A
Other languages
Spanish (es)
Inventor
Carl John Rose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES2004522A6 publication Critical patent/ES2004522A6/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Said procedure is characterized because it comprises the hydrogenation by catalytic transfer, in presence of cyclohexene, of a compound of formula (I), in which xey are each one of hydrogen atoms or togethers represent a second link between the carbon atoms to which they are united and r1 is a carboxi group or an ester group convertible in carboxi by hydrogenation. 4- (6 '' - metoxy-2 '' - naftil) butan-2-ona has application as anti-inflammatory. (Machine-translation by Google Translate, not legally binding)
ES8700373A 1986-02-15 1987-02-13 Novel manufacture of compound Expired ES2004522A6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868603772A GB8603772D0 (en) 1986-02-15 1986-02-15 Process

Publications (1)

Publication Number Publication Date
ES2004522A6 true ES2004522A6 (en) 1989-01-16

Family

ID=10593128

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8700373A Expired ES2004522A6 (en) 1986-02-15 1987-02-13 Novel manufacture of compound

Country Status (8)

Country Link
JP (1) JPS62195342A (en)
CH (1) CH670083A5 (en)
DK (1) DK75287A (en)
ES (1) ES2004522A6 (en)
GB (1) GB8603772D0 (en)
GR (1) GR870256B (en)
NL (1) NL8700356A (en)
SE (1) SE465925B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0267734B1 (en) * 1986-11-11 1994-01-26 Zeneca Limited Chemical compounds
US5756851A (en) * 1996-10-21 1998-05-26 Albemarle Corporation Production of nabumetone or precursors thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT343643B (en) * 1975-01-08 1978-06-12 Beecham Group Ltd PROCESS FOR MANUFACTURING NEW NAPHTHYL-SUBSTITUTED KETONS
EP0003074B1 (en) * 1978-01-07 1981-04-15 Beecham Group Plc Process for the preparation of 4-(6-methoxy-2-naphthyl)butan-2-one and 2-acetyl-3-(6-methoxy-2-naphthyl) propenoic acid esters

Also Published As

Publication number Publication date
SE8700592L (en) 1987-08-16
NL8700356A (en) 1987-09-01
SE465925B (en) 1991-11-18
DK75287A (en) 1987-08-16
JPS62195342A (en) 1987-08-28
GB8603772D0 (en) 1986-03-19
DK75287D0 (en) 1987-02-13
CH670083A5 (en) 1989-05-12
SE8700592D0 (en) 1987-02-13
GR870256B (en) 1987-06-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20041004