ES2012173A6 - Production of butanone derivative - Google Patents

Production of butanone derivative

Info

Publication number
ES2012173A6
ES2012173A6 ES8803820A ES8803820A ES2012173A6 ES 2012173 A6 ES2012173 A6 ES 2012173A6 ES 8803820 A ES8803820 A ES 8803820A ES 8803820 A ES8803820 A ES 8803820A ES 2012173 A6 ES2012173 A6 ES 2012173A6
Authority
ES
Spain
Prior art keywords
production
butanone derivative
naftil
metoxy
ona
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8803820A
Other languages
Spanish (es)
Inventor
Carl John Rose
Dales John Robert Mansfield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878729667A external-priority patent/GB8729667D0/en
Priority claimed from GB888823561A external-priority patent/GB8823561D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES2012173A6 publication Critical patent/ES2012173A6/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/512—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being a free hydroxyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Procedure for the preparation of a butanone derivative. A procedure for the preparation of 4- (6-metoxy-2-naftil) butan-2-ona which comprises to react a compound of formula (I) in which x is halo or a ghrupo o = c-cl with 3 buten -2-ol, de formula (II): in the presence of a catalyst of paladio. 4- (6-metoxy-2-naftil) butan-2-ona is useful for the treatment of arthritic conditions. (Machine-translation by Google Translate, not legally binding)
ES8803820A 1987-12-19 1988-12-16 Production of butanone derivative Expired - Lifetime ES2012173A6 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878729667A GB8729667D0 (en) 1987-12-19 1987-12-19 Novel process
GB888823561A GB8823561D0 (en) 1988-10-07 1988-10-07 Novel process

Publications (1)

Publication Number Publication Date
ES2012173A6 true ES2012173A6 (en) 1990-03-01

Family

ID=26293222

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8803820A Expired - Lifetime ES2012173A6 (en) 1987-12-19 1988-12-16 Production of butanone derivative

Country Status (6)

Country Link
JP (1) JPH02101038A (en)
CH (1) CH676237A5 (en)
DK (1) DK702388A (en)
ES (1) ES2012173A6 (en)
GR (1) GR1000163B (en)
NL (1) NL8803088A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2004042C (en) * 1988-12-08 1999-11-02 Napp Technologies, Inc. Method of preparation of nabumetone
US5756851A (en) * 1996-10-21 1998-05-26 Albemarle Corporation Production of nabumetone or precursors thereof
AU5656698A (en) * 1996-12-03 1998-06-29 Recordati S.A. Chemical And Pharmaceutical Company A process for the preparation of nabumetone
US5741938A (en) * 1997-02-21 1998-04-21 Albemarle Corporation Production of alkyl aralkyl keones from allylic-aralkenyl secondary alcohols

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1476721A (en) * 1974-08-20 1977-06-16 Beecham Group Ltd 4-6-methoxy-2-naphthyl-butan-2-one
US4070374A (en) * 1975-06-16 1978-01-24 Givaudan Corporation Process for the preparation of aryl substituted aldehydes, ketones and alcohols

Also Published As

Publication number Publication date
DK702388A (en) 1989-06-20
JPH02101038A (en) 1990-04-12
GR1000163B (en) 1991-10-10
DK702388D0 (en) 1988-12-16
CH676237A5 (en) 1990-12-28
NL8803088A (en) 1989-07-17

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2008-12-16