ES8302703A1 - Phenylquinolizidine - Google Patents

Phenylquinolizidine

Info

Publication number
ES8302703A1
ES8302703A1 ES512071A ES512071A ES8302703A1 ES 8302703 A1 ES8302703 A1 ES 8302703A1 ES 512071 A ES512071 A ES 512071A ES 512071 A ES512071 A ES 512071A ES 8302703 A1 ES8302703 A1 ES 8302703A1
Authority
ES
Spain
Prior art keywords
formula
radicals
several types
reaction
racematos
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES512071A
Other languages
Spanish (es)
Other versions
ES512071A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES8302703A1 publication Critical patent/ES8302703A1/en
Publication of ES512071A0 publication Critical patent/ES512071A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Procedure for the obtaining of phenylquinolicidins, in the form of racematos or of the enantiomers and of their acid addition salts, of formula (I), in which x, and and can be several types of radicals. Consists of the condensation reaction of a formula (II) phenylendiamine, with a cyclizing agent, of formula r <011> -co-r <069> are halogen, amino or 1-imidazolyl and yx, and, ryr can be several types of radicals. The reaction is carried out following conventional methods. These compounds have pharmacological applications for their neuroletic, antimimetic and/or analgesic activities. (Machine-translation by Google Translate, not legally binding)
ES512071A 1980-04-11 1982-05-11 "A PROCEDURE FOR THE PREPARATION OF PHENYL-QUINOLICIDINS". Granted ES512071A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH278480 1980-04-11

Publications (2)

Publication Number Publication Date
ES8302703A1 true ES8302703A1 (en) 1983-02-01
ES512071A0 ES512071A0 (en) 1983-02-01

Family

ID=4241517

Family Applications (4)

Application Number Title Priority Date Filing Date
ES512074A Expired ES8302704A1 (en) 1980-04-11 1982-05-11 Phenylquinolizidine
ES512071A Granted ES512071A0 (en) 1980-04-11 1982-05-11 "A PROCEDURE FOR THE PREPARATION OF PHENYL-QUINOLICIDINS".
ES512072A Expired ES8302706A1 (en) 1980-04-11 1982-05-11 Phenylquinolizidine
ES512073A Granted ES512073A0 (en) 1980-04-11 1982-05-11 "A PROCEDURE FOR THE PREPARATION OF PHENYL-QUINOLICIDINE

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES512074A Expired ES8302704A1 (en) 1980-04-11 1982-05-11 Phenylquinolizidine

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES512072A Expired ES8302706A1 (en) 1980-04-11 1982-05-11 Phenylquinolizidine
ES512073A Granted ES512073A0 (en) 1980-04-11 1982-05-11 "A PROCEDURE FOR THE PREPARATION OF PHENYL-QUINOLICIDINE

Country Status (7)

Country Link
JP (1) JPS56158783A (en)
KR (1) KR830005219A (en)
BR (1) BR8102218A (en)
CS (1) CS222700B2 (en)
ES (4) ES8302704A1 (en)
GR (1) GR74868B (en)
ZA (1) ZA812285B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019134985A1 (en) * 2018-01-08 2019-07-11 F. Hoffmann-La Roche Ag Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors

Also Published As

Publication number Publication date
CS222700B2 (en) 1983-07-29
GR74868B (en) 1984-07-12
ES512072A0 (en) 1983-02-01
ES512074A0 (en) 1983-02-01
ES512071A0 (en) 1983-02-01
ES8302706A1 (en) 1983-02-01
ZA812285B (en) 1982-04-28
BR8102218A (en) 1981-10-13
ES8302707A1 (en) 1983-02-01
KR830005219A (en) 1983-08-03
JPS56158783A (en) 1981-12-07
ES512073A0 (en) 1983-02-01
ES8302704A1 (en) 1983-02-01

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