ES297718A1 - Procedure for the preparation of new derivatives of imidazole (Machine-translation by Google Translate, not legally binding) - Google Patents

Abstract

Process for the preparation of new imidazole derivatives, of the general formula I ** (See formula) ** where R1 means hydrogen, a lower alkyl group or a dialkylamino alkyl group, R2 means hydrogen or a lower alkyl group, the lower alkyl groups R1 and R2 being able to be linked to each other directly or by means of an oxygen atom, R3 means an alkyl or lower alkoxy group, a halogen atom or a nitro or trifluor or methyl group, R4 means hydrogen, a lower alkyl group or a halogen atom and X means oxygen or sulfur, characterized by reacting a reactive ester, relative to the primary hydroxyl group, of a compound of the general formula II ** (See formula) ** where X, R3 and R4 have the meaning set forth above, with a compound of the general formula III ** (See formula) ** wherein R1 and R2 have the meaning set forth above, in the presence of an acid-binding agent, and to be transformed, the compound of the general formula I obtained, if desired, in a salt with an inorganic or organic acid. (Machine-translation by Google Translate, not legally binding)